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Fentanyl

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Identification
Molecular formula
C22H28N2O
CAS number
437-38-7
IUPAC name
(3-allyl-1-methyl-4-phenyl-4-piperidyl) propanoate
State
State

At room temperature, fentanyl is generally found as a solid in the form of a powder. In some cases, it may be part of a solution if prepared for medical administration by healthcare professionals.

Melting point (Celsius)
87.50
Melting point (Kelvin)
360.65
Boiling point (Celsius)
48.50
Boiling point (Kelvin)
321.65
General information
Molecular weight
336.47g/mol
Molar mass
336.4690g/mol
Density
1.0050g/cm3
Appearence

Fentanyl appears as a white or slightly off-white powder. In some cases, it might be encountered as a clear or off-white solution when used in medical settings, particularly for intravenous, intramuscular, or transdermal applications. However, in illicit uses or preparations, it may be found in various forms, including tablets or mixed with other substances.

Comment on solubility

Solubility of (3-allyl-1-methyl-4-phenyl-4-piperidyl) propanoate

The solubility of (3-allyl-1-methyl-4-phenyl-4-piperidyl) propanoate can be understood through a few critical factors:

  • Polarity: The compound contains polar functional groups that may influence its interaction with solvents.
  • Hydrogen Bonding: The ability to form hydrogen bonds can enhance solubility in polar solvents like water.
  • Molecular Size: As a larger molecule, solubility might decrease in highly polar solvents due to steric hindrance.

Generally, solubility can vary significantly depending on the solvent used. Here are some potential solubility characteristics:

  • Likely to be more soluble in organic solvents such as ethanol or dichloromethane.
  • Potentially less soluble in water due to its relatively complex structure.

In conclusion, the solubility of (3-allyl-1-methyl-4-phenyl-4-piperidyl) propanoate is influenced by its chemical structure, which defines how it interacts with various solvents. Understanding these interactions can provide insights into potential applications and behaviors in different environments.

Interesting facts

Interesting Facts About (3-Allyl-1-methyl-4-phenyl-4-piperidyl) Propanoate

(3-Allyl-1-methyl-4-phenyl-4-piperidyl) propanoate is an intriguing compound that captivates chemists and researchers alike due to its unique structural features and potential applications. Here are some interesting aspects of this compound:

  • Novel Structure: This compound belongs to the class of piperidine derivatives, characterized by a six-membered ring containing nitrogen. The presence of both allyl and phenyl groups enhances its chemical diversity.
  • Biological Significance: Compounds like (3-allyl-1-methyl-4-phenyl-4-piperidyl) propanoate are often investigated for their pharmacological properties. They may exhibit activity related to nerve signaling, making them subjects of interest in neuropharmacology.
  • Medicinal Chemistry: Researchers examine derivatives of piperidine for various therapeutic uses, including their potential as analgesics, antidepressants, and anti-anxiety agents. The synthesis and modification of this compound can lead to the discovery of new medicinal agents.
  • Synthetic Pathways: The synthesis of (3-allyl-1-methyl-4-phenyl-4-piperidyl) propanoate can involve multiple steps, which can serve as a great educational example in organic chemistry courses to illustrate reaction mechanisms, functional group interconversions, and the importance of chirality.
  • Future Research: Given the compound's unique properties, ongoing studies may unlock new insights into its mechanisms of action and interactions with biological targets, driving forward the research in areas like drug development and therapeutic applications.

Overall, (3-Allyl-1-methyl-4-phenyl-4-piperidyl) propanoate stands out not only for its structural complexity but also for its significance in the realms of chemistry and medicine, making it a compound worth exploring for students and professionals alike.

Synonyms
Allylprodine
Alperidine
25384-17-2
Allilprodina
Allylprodinum
Aliprodina
Allilprodina [DCIT]
alilprodina
Ro 2-7113
Aliprodina [INN-Spanish]
Allylprodinum [INN-Latin]
NIH 7440
UNII-4343OEZ18O
Allylprodine [INN:BAN:DCF]
DEA No. 9602
4-Piperidinol, 1-methyl-4-phenyl-3-(2-propenyl)-, propanoate (ester)
ACSCN-9602
IDS-NA-007
4-Piperidinol, 3-allyl-1-methyl-4-phenyl-, propionate (ester)
DTXSID80865210
4343OEZ18O
NIH-7440
3-Allyl-1-methyl-4-phenyl-4-propionyloxypiperidine
Allylprodine (INN)
alpha-3-Allyl-1-methyl-4-phenyl-4-propionoxypiperidine
Propionic acid, 3-allyl-1-methyl-4-phenyl-4-piperidyl ester
Aliprodina (INN-Spanish)
ALLYLPRODINE [INN]
Allylprodinum (INN-Latin)
.alpha.-3-Allyl-1-methyl-4-phenyl-4-propionoxypiperidine
1-Methyl-4-phenyl-3-(2-propenyl)-4-piperidinol propanoate
1-methyl-4-phenyl-3-(prop-2-en-1-yl)piperidin-4-yl propanoate
RefChem:110915
ALLYLPRODINE [MI]
DTXCID60220868
KGYFOSCXVAXULR-UHFFFAOYSA-N
SCHEMBL24416
CHEMBL2103995
AKOS015842723
DB01542
D12662
Q4062649
3-Allyl-1-methyl-4-phenyl-4-piperidinyl propionate #