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Noscapine

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Identification
Molecular formula
C22H23NO7
CAS number
128-62-1
IUPAC name
3-allyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7,9-diol
State
State

At room temperature, noscapine is in a solid state, typically found as a crystalline powder.

Melting point (Celsius)
176.00
Melting point (Kelvin)
449.15
Boiling point (Celsius)
420.00
Boiling point (Kelvin)
693.15
General information
Molecular weight
413.44g/mol
Molar mass
413.4560g/mol
Density
1.3000g/cm3
Appearence

Noscapine appears as a white to off-white crystalline powder. It is odorless and has a bitter taste.

Comment on solubility

Solubility of 3-allyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7,9-diol

The solubility of the compound 3-allyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7,9-diol (C22H23NO7) is a complex subject that is influenced by various factors, including structural characteristics and environmental conditions. Understanding solubility can help in predicting how this compound behaves in different mediums.

Key Aspects of Solubility

  • Polarity: The presence of hydroxyl (-OH) groups generally increases solubility in polar solvents like water.
  • Molecular Size: As the molecular weight rises, solubility in non-polar solvents may improve, while the same can decrease in polar solvents.
  • Hydrogen Bonding: Compounds that can form hydrogen bonds typically show enhanced solubility in polar solvents.
  • Temperature: Many organic compounds’ solubility increases with temperature, making it an important factor in practical applications.

For 3-allyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7,9-diol, initial assessments may indicate variable solubility in aqueous and organic solvents. Researchers are advised to perform empirical tests to determine specific solubility measurements, as theoretical predictions can sometimes be misleading.

In conclusion, the solubility of this compound is not a straightforward determination, and the aforementioned factors should be taken into account for any experimental and application-based evaluations.

Interesting facts

Exploring 3-Allyl-2,4,4a,7,7a,13-Hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7,9-diol

The compound known as 3-allyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7,9-diol is a fascinating member of the isoquinoline family, known for its structural complexity and biological activity. Here are some interesting facts about this unique compound:

  • Structural Diversity: This compound features a multi-ring structure that combines elements of both benzofuro and isoquinoline, which contributes to its unique reactivity and interaction with biological systems.
  • Pharmacological Interest: Compounds related to isoquinoline are often studied for their potential medicinal properties, including antitumor and anti-inflammatory activity, making them important in pharmaceutical research.
  • Synthetic Routes: The synthesis of such complex molecules often involves intricate organic reactions, demonstrating the innovative techniques chemists employ to construct these compounds.
  • Variability in Applications: The diverse functional groups present in this compound allow it to be explored for varied applications, which may range from natural product synthesis to materials science.
  • Biological Interactions: Studies on compounds like this one may reveal how they interact at the molecular level with biological targets, shedding light on their mechanisms of action in living organisms.

As with many compounds in the field of medicinal chemistry, ongoing research could uncover even more applications and advantages. The blend of complexity and potential makes this compound a captivating topic for both chemists and pharmacologists alike.

Synonyms
Lethidrone
Letidron
Allylnormorphine
N-Allylnormorphine
Morphinan-3,6.alpha.-diol, 17-allyl-7,8-didehydro-4,5.alpha.-epoxy-
Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-(2-propenyl)-, (5.alpha.,6.alpha.)-
3-prop-2-enyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7,9-diol
17-Allyl-7,8-didehydro-4,5.alpha.-epoxymorphinan-3,6.alpha.-diol
CHEMBL611473
Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-(2-propen-1-yl)-, (5.alpha.,6.alpha.)-
L000967