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3-amino-2-fluoropropanoic acid

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Identification
Molecular formula
C3H6FNO2
CAS number
75127-34-3
IUPAC name
3-amino-2-fluoro-propanoic acid
State
State

At room temperature, 3-amino-2-fluoropropanoic acid is typically found in a solid state as a crystalline powder. It is stable under standard conditions.

Melting point (Celsius)
162.00
Melting point (Kelvin)
435.15
Boiling point (Celsius)
225.90
Boiling point (Kelvin)
499.05
General information
Molecular weight
107.09g/mol
Molar mass
107.0920g/mol
Density
1.2830g/cm3
Appearence

3-Amino-2-fluoropropanoic acid is a white crystalline solid. It generally appears as a fine powder and is typically odorless. The compound's appearance may also include slight off-white hues depending on its purity and form.

Comment on solubility

Solubility of 3-amino-2-fluoro-propanoic acid

3-amino-2-fluoro-propanoic acid, a compound with both amino and carboxylic acid functional groups, displays notable solubility characteristics. Its ability to dissolve in various solvents can be attributed to the presence of polar functional groups.

Key Solubility Properties:

  • High Water Solubility: As a carboxylic acid, it is highly soluble in water due to hydrogen bonding.
  • Compatibility with Polar Solvents: Beyond water, it shows good solubility in other polar solvents such as methanol and ethanol.
  • Limited Solubility in Nonpolar Solvents: Conversely, 3-amino-2-fluoro-propanoic acid is likely to be poorly soluble in nonpolar solvents like hexane, owing to its polar nature.

As a general rule, acids with both amino and carboxylic groups tend to have enhanced solubility in aqueous solutions. As such, one might say, "The more 'functional' a molecule, the better its solubility prospects in polar environments." This solubility characteristic makes 3-amino-2-fluoro-propanoic acid of interest in various chemical applications, especially in biochemistry and pharmaceutical formulations.

Interesting facts

Interesting Facts about 3-Amino-2-Fluoro-Propanoic Acid

3-Amino-2-fluoro-propanoic acid is a fascinating compound that plays a significant role in various scientific and medicinal applications. Here are some engaging insights:

  • Amino Acid Derivative: This compound is a derivative of amino acids, specifically α-amino acids, which are the building blocks of proteins. They share a central carbon atom bonded to an amino group, a carboxyl group, and a side chain.
  • Fluorine's Role: The presence of fluorine in this compound can profoundly influence its biochemical properties. Fluorinated amino acids are often studied for their potential to modify biological pathways and enhance the rigidity of peptides and proteins.
  • Potential Applications: Due to its unique structure, 3-amino-2-fluoro-propanoic acid has garnered interest in medicinal chemistry, especially as a potential lead compound for drug development aimed at specific receptor targets.
  • Chirality: The molecule is chiral, meaning it exists in two enantiomeric forms, which can have significantly different biological activities. This chirality is crucial in the drug design as it determines how the molecule interacts with biological systems.

In summary, 3-amino-2-fluoro-propanoic acid is not merely a simple chemical entity but a gateway to understanding intricate biochemical interactions and the design of novel therapeutic agents. Its complex features and potential applications make it an exciting subject of study in the field of chemistry.

Synonyms
3821-81-6
3-amino-2-fluoropropanoic acid
alpha-Fluoro-beta-alanine
3-Amino-2-fluoropropionic acid
2-Fluoro-beta-alanine
2-Fluoro-.beta.-alanine
Propanoic acid, 3-amino-2-fluoro-
EINECS 223-318-3
FLUORO-.BETA.-ALANINE
1461S5575Q
DTXSID00959160
.ALPHA.-FLUORO-.BETA.-ALANINE
DTXCID10835284
dl-2-Fluoro-3-alanine
a-fluoro-b-alanine
MFCD00041324
CHEBI:80626
|A-fluoro-|A-alanine
UNII-1461S5575Q
Propanoic acid, 3-amino-2-fluoro-; ss-Alanine, 2-fluoro- (6CI,7CI,8CI); 3-Amino-2-fluoropropanoic acid; 2-Fluoro-ss-alanine; Fluoro-ss-alanine; a-Fluoro-ss-alanine
a-fluoro-beta-alanine
2-Fluoro-beta-alanine #
DL-2-Fluoro-beta-alanine
DL-3-Fluoro-beta-alanine
?-FLUORO-?-ALANINE
3-amino-2-fluoropropanoicacid
alpha -Fluoro- beta -alanine
SCHEMBL637248
CHEMBL3544571
alpha-Fluoro-ss-alanine (FBAL)
BBL103051
STL556860
(RS)-3-amino-2-fluoropropionic acid
AKOS005255703
3-Amino-2-fluoropropionic acid, 95%
CS-W011291
MS-20544
NS00044892
EN300-220566
Q27149674
InChI=1/C3H6FNO2/c4-2(1-5)3(6)7/h2H,1,5H2,(H,6,7