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Serine

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Identification
Molecular formula
C3H7NO3
CAS number
56-45-1
IUPAC name
3-amino-2-hydroxy-propanoic acid
State
State

Serine is typically found in a solid state at room temperature.

Melting point (Celsius)
228.00
Melting point (Kelvin)
501.00
Boiling point (Celsius)
266.00
Boiling point (Kelvin)
539.00
General information
Molecular weight
105.09g/mol
Molar mass
105.0920g/mol
Density
1.6030g/cm3
Appearence

Serine is a white crystalline solid. It is often available in the form of a crystalline powder and is odorless.

Comment on solubility

Solubility of 3-amino-2-hydroxy-propanoic acid

3-amino-2-hydroxy-propanoic acid, also known as serine, is characterized by its high solubility in water, which can be attributed to its polar functional groups. The solubility of this compound can be described through the following key points:

  • Hydrophilic Nature: The presence of both an amino group (-NH2) and a hydroxyl group (-OH) enables C3H7NO3 to engage in strong hydrogen bonding with water molecules, enhancing its solubility.
  • Temperature Dependency: Like many amino acids, the solubility of C3H7NO3 typically increases with temperature, making it even more soluble when dissolved in warm water.
  • pH Influence: The acidic and basic properties of C3H7NO3 can lead to variations in solubility; at different pH levels, it may exist predominantly in its zwitterionic form, which is highly soluble in aqueous solutions.

In summary, the solubility of 3-amino-2-hydroxy-propanoic acid is influenced by its molecular structure and the environmental conditions, making it an important compound in biochemical processes. As an amino acid, it plays a crucial role in protein synthesis and metabolic functions, further highlighting the significance of its solubility in biological systems.

Interesting facts

Interesting Facts about 3-Amino-2-hydroxy-propanoic Acid

3-Amino-2-hydroxy-propanoic acid, also known as serine, is an important amino acid with a diverse range of functions in both biology and chemistry.

Biological Significance

Serine plays a crucial role in the synthesis of proteins as it is one of the 20 standard amino acids used by cells. Here are some key points:

  • It's classified as a non-essential amino acid, meaning that our bodies can synthesize it from other compounds.
  • Serine is involved in the biosynthesis of other amino acids, such as glycine and cysteine.
  • It serves as a precursor for the synthesis of over 200 protein structures, influencing numerous cellular functions.

Role in Metabolism

In metabolism, serine is significant for:

  • Participating in one-carbon metabolism, which is crucial for DNA and RNA synthesis.
  • Supporting the production of phospholipids for cellular membranes, which are vital for cell structure and signaling.

Research Insights

Research has unveiled intriguing insights about serine:

  • It has potential implications in neurological health, as it is involved in neurotransmitter synthesis.
  • Studies have shown a correlation between serine levels and certain diseases, including cancer and neurodegenerative conditions.

Chemical Properties and Uses

From a chemical perspective, serine features:

  • A polar hydroxyl group, which allows it to participate in hydrogen bonding, affecting protein structure and function.
  • Its involvement in the synthesis of important biomolecules such as sphingolipids and nucleotides.

In conclusion, 3-amino-2-hydroxy-propanoic acid is not just another amino acid; it is a versatile compound that bridges chemistry and biology, showcasing nature’s intricate design and the molecular interconnections that sustain life. As research continues to unravel its mysteries, serine's importance in health and disease becomes increasingly evident.

Synonyms
565-71-9
3-amino-2-hydroxypropanoic acid
ISOSERINE
Propanoic acid, 3-amino-2-hydroxy-
2-Hydroxy-3-aminopropanoic acid
815-213-1
918-962-3
dl-Isoserine
632-12-2
H-DL-ISOSER-OH
(DL)-Isoserine
3-Amino-2-hydroxypropionic acid
MFCD00008138
(R)-Isoserine
U7LTG62FEW
2-Hydroxy-.beta.-alanine
CHEMBL4798809
MFCD03428326
H-DL-beta-Amino-alpha-hydroxypropionic acid
(S)-3-Amino-2-hydroxypropionic acid
(RS)-isoserine
Isoserine, DL-
(2R)-3-Amino-2-hydroxy-propanoic acid
DL-3-Amino-2-hydroxypropionic Acid
(+/-)-Isoserine
H-DL-Ise-OH
DL-Isoserine, 98%
UNII-U7LTG62FEW
3-AMINOLACTIC ACID
SCHEMBL85839
DTXSID70870737
ALBB-031572
H-DL--Amino--hydroxypropionic acid
DL-3-Amino-2-hydroxypropanoic acid
BDBM50563978
(R)-3-Amino-2-hydroxypropionic Acid
AKOS009157084
AB88677
CS-W013682
FI45395
HY-W012966
(2rs)-3-amino-2-hydroxypropanoic acid
AS-35426
BP-13413
DA-04187
DA-64570
PD196866
SY007745
SY013665
SY013666
DB-054433
3-aMino-2-hydroxypropionic acid,dl-isoserine
I0309
EN300-95550
F8885-0613