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Phentermine Hydrochloride

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Identification
Molecular formula
C10H15ClN
CAS number
1197-21-3
IUPAC name
3-amino-2-methyl-1,1-diphenyl-propan-1-ol;hydrochloride
State
State

At room temperature, phentermine hydrochloride is typically found in a solid state, appearing as a crystalline powder.

Melting point (Celsius)
215.00
Melting point (Kelvin)
488.15
Boiling point (Celsius)
361.80
Boiling point (Kelvin)
634.95
General information
Molecular weight
267.79g/mol
Molar mass
267.7880g/mol
Density
0.9912g/cm3
Appearence

Phentermine hydrochloride typically appears as a white or almost white crystalline powder. It is known for its hygroscopic properties and is often odorless.

Comment on solubility

Solubility of 3-amino-2-methyl-1,1-diphenyl-propan-1-ol;hydrochloride

The solubility of 3-amino-2-methyl-1,1-diphenyl-propan-1-ol; hydrochloride is influenced by several factors due to its unique molecular structure. Generally speaking, this compound is:

  • Soluble in water: The presence of the hydrochloride form increases its hydrophilicity, enhancing solubility in aqueous solutions.
  • Influenced by pH: The solubility may vary with changes in pH levels; as it is an ammonium salt, alterations in acidity can affect its ionization state.
  • Limited solubility in organic solvents: Due to its polar nature, it may demonstrate lower solubility in non-polar organic solvents.

In practical applications, understanding the solubility is crucial for:

  1. Preparation of pharmaceutical formulations.
  2. Determining the compound's bioavailability.
  3. Predicting behavior in biological systems.

As quoted from chemical solubility principles: “A compound that ionizes in solution is typically more soluble than its non-ionized counterpart.” Hence, for 3-amino-2-methyl-1,1-diphenyl-propan-1-ol; hydrochloride, the ionic nature plays a significant role in granting it favorable solubility characteristics.

Interesting facts

Interesting Facts about 3-Amino-2-methyl-1,1-diphenyl-propan-1-ol Hydrochloride

This compound, a hydrochloride salt, belongs to a class of organic compounds that are significant in medicinal chemistry. As a scientist or chemistry student, understanding its molecular characteristics and potential applications can open avenues for innovative research. Here are some noteworthy points about 3-amino-2-methyl-1,1-diphenyl-propan-1-ol hydrochloride:

  • Pharmacological Importance: This compound can act as a precursor or an active pharmaceutical ingredient (API) in various therapeutic applications, particularly in the development of CNS (Central Nervous System) agents.
  • Structure Activity Relationship (SAR): The unique combination of the amino group and the diphenyl structure allows for interesting interactions within biological systems, which can be critical for designing effective drugs.
  • Chirality: The presence of multiple chiral centers in the compound adds complexity to its behavior in biological systems, making chirality an essential consideration during synthesis and formulation.
  • Synthesis Routes: Different synthetic pathways can be explored to produce this compound, potentially leading to environmentally friendly methods. Motivation towards green chemistry practices is vital in today’s research landscape.
  • Research Potential: There is an ongoing interest in assessing the compound’s effectiveness in treating neurological disorders or its role in synthesizing more complex molecules for drug design.

As researchers delve into the properties of 3-amino-2-methyl-1,1-diphenyl-propan-1-ol hydrochloride, they continually reveal its multifaceted roles within biochemical pathways. The blend of chemistry and pharmacology serves as a reminder of the vast ecosystems created by even the simplest compounds!

Synonyms
2-Mdp hydrochloride
14185-07-0
TJH732RKT9
1,1-Diphenyl-2-methyl-3-aminopropanol hydrochloride
97T719D55D
Benzhydrol, alpha-(2-amino-1-methylethyl)-, hydrochloride
14185-05-8
1-Propanol, 3-amino-1,1-diphenyl-2-methyl-, (L)-
d-1,1-Diphenyl-2-methyl-3-aminopropanol hydrochloride
l-1,1-Diphenyl-2-methyl-3-aminopropanol hydrochloride
alpha-(2-Amino-1-methylethyl)benzhydrol hydrochloride (D)-
alpha-(2-Amino-1-methylethyl)benzhydrol hydrochloride (L)-
1-Propanol, 3-amino-1,1-diphenyl-2-methyl-, hydrochloride, (D)-
Benzhydrol, alpha-(2-amino-1-methylethyl)-, hydrochloride, (D)-
Benzhydrol, alpha-(2-amino-1-methylethyl)-, hydrochloride, (L)-
UNII-TJH732RKT9
alpha-(2-Amino-1-methylethyl)benzhydrol hydrochloride
UNII-97T719D55D
DTXSID50931214
(-)-2-MDP HYDROCHLORIDE
Benzenemethanol, .alpha.-(2-amino-1-methylethyl)-.alpha.-phenyl-, hydrochloride, (-)-
14185-09-2
alpha-(2-Amino-1-methylethyl)benzhydrol hydrochloride, (-)-
3-Amino-2-methyl-1,1-diphenylpropan-1-ol--hydrogen chloride (1/1)
Benzhydrol, alpha-(2-amino-1-methylethyl)-, hydrochloride, (+/-)-
.ALPHA.-(2-AMINO-1-METHYLETHYL)BENZHYDROL HYDROCHLORIDE, (-)-
Benzenemethanol, alpha-(2-amino-1-methylethyl)-alpha-phenyl-, hydrochloride
BENZHYDROL, .ALPHA.-(2-AMINO-1-METHYLETHYL)-, HYDROCHLORIDE, (-)-
Benzenemethanol, .alpha.-(2-amino-1-methylethyl)-.alpha.-phenyl-, hydrochloride
BENZHYDROL, .ALPHA.-(2-AMINO-1-METHYLETHYL)-, HYDROCHLORIDE, (+/-)-