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Metanilic Acid

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Identification
Molecular formula
C6H7NO4S
CAS number
121-47-1
IUPAC name
3-amino-4-hydroxy-benzenesulfonic acid
State
State

Metanilic acid is typically found as a solid at room temperature.

Melting point (Celsius)
282.00
Melting point (Kelvin)
555.15
Boiling point (Celsius)
311.00
Boiling point (Kelvin)
584.15
General information
Molecular weight
173.19g/mol
Molar mass
173.1860g/mol
Density
1.4850g/cm3
Appearence

Metanilic acid appears as light brown to yellowish crystals or powder. It is soluble in water, giving a pale yellow solution.

Comment on solubility

Solubility of 3-amino-4-hydroxy-benzenesulfonic acid

3-amino-4-hydroxy-benzenesulfonic acid, also known as pars amino, exhibits notable solubility characteristics in various solvents. Here are some essential points regarding its solubility:

  • Water Solubility: This compound is highly soluble in water due to the presence of both amino and hydroxyl functional groups, which can form hydrogen bonds with water molecules.
  • Solvent Interactions: In addition to water, 3-amino-4-hydroxy-benzenesulfonic acid can also dissolve in alcohols and other polar solvents, enhancing its usability across different chemical applications.
  • Temperature Effects: Its solubility generally increases with temperature, making it easier to work with in heated solutions for synthesis and reactions.

Overall, the solubility profile of 3-amino-4-hydroxy-benzenesulfonic acid underscores its versatile nature in both laboratory and industrial settings. The ability to readily dissolve in polar solvents makes it an invaluable compound in various formulations and reactions.

Interesting facts

Interesting Facts About 3-Amino-4-Hydroxy-Benzenesulfonic Acid

3-Amino-4-hydroxy-benzenesulfonic acid, commonly referred to as Sulfanilic Acid, is an intriguing compound with a rich history and diverse applications in various fields of chemistry. Let's delve into some fascinating aspects of this compound:

  • Biological Relevance: Sulfanilic acid is important in biochemical research as a precursor for the synthesis of various azo dyes. These dyes are widely employed in textiles and food industries, showcasing the compound's significant impact on commercial applications.
  • Historical Significance: Discovered in the early 20th century, 3-amino-4-hydroxy-benzenesulfonic acid played a pivotal role in the development of sulfa drugs. These antibacterial agents revolutionized medicine and laid the foundation for modern antibiotics.
  • Analytical Chemistry: This compound is also utilized in analytical chemistry as a reagent. It can be used to detect and quantify nitrite ions in water, highlighting its role in environmental monitoring.
  • Structure and Function: The presence of both an amino group and a hydroxy group in its structure allows for various chemical interactions, making it versatile for synthesis. Its sulfonic acid group enhances its solubility in water, facilitating its use in chemical reactions.
  • Safety Considerations: While widely used, it's essential to handle this compound with care. Laboratory safety protocols suggest using appropriate personal protective equipment (PPE) when working with chemicals like sulfanilic acid to avoid any adverse effects.

In summary, 3-amino-4-hydroxy-benzenesulfonic acid is more than just a chemical compound; it holds a significant place in scientific, industrial, and medical arenas. Its wide range of applications and contributions to science makes it a prime topic of interest for both chemists and biochemists alike.

Synonyms
3-Amino-4-hydroxybenzenesulfonic acid
98-37-3
2-AMINOPHENOL-4-SULFONIC ACID
4-Hydroxymetanilic acid
2-Amino-1-phenol-4-sulfonic acid
2-Amino-4-sulfophenol
Benzenesulfonic acid, 3-amino-4-hydroxy-
o-Aminophenol-p-sulfonic acid
2-Hydroxy-5-sulfoaniline
4-Hydroxy-3-aminobenzenesulfonic acid
Metanilic acid, 4-hydroxy-
CCRIS 4584
AI3-14898
NSC 1491
EINECS 202-662-8
3-Amino-4-hydroxybenzenesulphonic acid
3-amino-4-hydroxybenzene-1-sulfonic acid
DTXSID5024500
4WE7CX7RD5
DTXCID404500
EC 202-662-8
NSC-1491
1-AMINO-2-HYDROXY-5-BENZENESULFONIC ACID
2Amino4sulfophenol
2Hydroxy5sulfoaniline
3-amino-4-hydroxy-benzenesulfonic acid
4Hydroxymetanilic acid
oAminophenolpsulfonic acid
Metanilic acid, 4hydroxy
2Aminophenol4sulfonic acid
UNII-4WE7CX7RD5
2Aminophenol4sulphonic acid
2Amino1phenol4sulfonic acid
SCHEMBL156846
2-aminophenol-4-sulphonic acid
aniline, 2-hydroxy-5-sulpho-
orthoAminophenolparasulfonic acid
CHEMBL1455467
Metanilic acid, 4hydroxy (8CI)
NSC1491
4Hydroxy3aminobenzenesulfonic acid
3Amino4hydroxybenzenesulphonic acid
1Amino2hydroxy5benzenesulfonic acid
3Amino4hydroxy benzenesulfonic acid
ALBB-025872
2-Amino-1-phenol-4-sulphonic acid
3-Amino-4-hydroxybenzenesulfonicacid
Benzenesulfonic acid, 3amino4hydroxy
Tox21_201044
1-Phenol-4-sulfonic acid, 2-amino
AKOS003620534
Amino-1-phenol-4-sulfonic acid, 2-
CAS-98-37-3
3-AMINO-4-HYDROXY SULFONIC ACID
NCGC00091448-01
NCGC00091448-02
NCGC00258597-01
1-Hydroxy-2-aminobenzene-4-sulfonic acid
AC-10750
LS-13127
Benzenesulphonic acid, 3-amino-4-hydroxy-
A0399
NS00002269
ORTHO-AMINO-PHENOL-PARA-SULFONIC ACID
3-AMINO-4-HYDROXY BENZENESULFONIC ACID
3-AMINO-4-HYDROXYBENZENE SULFONIC ACID
E70308
EN300-126715
AG-690/12764372
benzenesulfonic acid, 3-amino-4-hydroxy-, semihydrate
Q20059738
3-Amino-4-hydroxybenzenesulfonic acid, technical, >=95% (T)
BENZENESULFONIC ACID,3-AMINO,4-HYDROXY 2-AMINO,4-SULFOPHENOL
BENZENESULFONIC ACID,3-AMINO,4-HYDROXY 2-AMINO,4-SULFOPHENOL
2-amino-9-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl]-3H-purin-6-one