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3-amino-4-methoxy-N-phenyl-benzamide

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Identification
Molecular formula
C14H14N2O2
CAS number
1202-66-6
IUPAC name
3-amino-4-methoxy-N-phenyl-benzamide
State
State

At room temperature, 3-amino-4-methoxy-N-phenyl-benzamide is usually in a solid state.

Melting point (Celsius)
219.00
Melting point (Kelvin)
492.00
Boiling point (Celsius)
540.00
Boiling point (Kelvin)
813.00
General information
Molecular weight
242.28g/mol
Molar mass
242.2760g/mol
Density
1.2940g/cm3
Appearence

This compound appears as a crystalline solid that is typically white or off-white in color. It tends to be soluble in organic solvents and is generally stable under normal conditions.

Comment on solubility

Solubility of 3-amino-4-methoxy-N-phenyl-benzamide

The solubility of 3-amino-4-methoxy-N-phenyl-benzamide in various solvents is influenced by several factors including molecular structure, polarity, and temperature. Below are key points regarding its solubility:

  • Polar vs. Nonpolar Solvents: This compound features both polar amine and methoxy groups that could promote solubility in polar solvents such as water and alcohols. However, its overall structure may also enhance solubility in nonpolar solvents.
  • Temperature Dependence: Like many organic compounds, solubility can increase with temperature. Heating the solvent may result in a greater dissolution rate.
  • pH Sensitivity: The presence of the amino group can affect solubility at different pH levels, possibly rendering 3-amino-4-methoxy-N-phenyl-benzamide more soluble in basic conditions due to protonation effects.
  • Hydrogen Bonding: The capability to form hydrogen bonds from the amine and methoxy groups may further enhance solubility in polar solvents.

In summary, the solubility of 3-amino-4-methoxy-N-phenyl-benzamide is multifaceted and can vary significantly depending on the solvent environment and the conditions applied. Careful consideration of these factors is essential for applications in chemical processes.

Interesting facts

Interesting Facts about 3-Amino-4-methoxy-N-phenyl-benzamide

The compound 3-amino-4-methoxy-N-phenyl-benzamide, often referred to in research and development as a potential pharmacological agent, offers a fascinating insight into the world of medicinal chemistry. Below are some noteworthy aspects of this compound:

Structural Insights

  • Aromatic Properties: The compound contains multiple aromatic rings, which can contribute to its potential biological activity, particularly in drug design.
  • Functional Groups: The presence of an amino group and a methoxy group suggests its role in hydrogen bonding and electron donation, which may enhance its reactivity with biological targets.

Potential Applications

  • Pharmaceutical Development: This compound has garnered attention for its potential use in developing treatments for various diseases, including cancer and inflammatory conditions.
  • Research Interest: It serves as a model compound in studying structure-activity relationships in medicinal chemistry, helping researchers understand how modifications to its structure can influence biological efficacy.

Scientific Importance

As a member of the benzamide class, 3-amino-4-methoxy-N-phenyl-benzamide is a prime candidate for studies in:

  • Drug Action: Understanding how the modifications to its structure can impact pharmacodynamics and pharmacokinetics.
  • Toxicology: Evaluating the safety profile and potential side effects as it pertains to developing therapeutic interventions.

In conclusion, 3-amino-4-methoxy-N-phenyl-benzamide is not just a chemical compound; it is an intriguing subject of study that weaves together the principles of organic chemistry with the vital aim of enhancing human health through innovative drug design. As a researcher or student in the field, diving deeper into its chemical behavior and potential therapeutic applications could lead to groundbreaking discoveries.

Synonyms
3-Amino-4-methoxybenzanilide
120-35-4
3-Amino-4-methoxy-N-phenylbenzamide
3-Amino-p-anisanilide
Benzamide, 3-amino-4-methoxy-N-phenyl-
p-Anisanilide, 3-amino-
3-Amino-4-methoxy benzanilide
BENZANILIDE, 3-AMINO-4-METHOXY-
EINECS 204-388-4
NSC 50647
V5Y646AW8S
MFCD00017166
NSC-50647
DTXSID0051607
LHMQDVIHBXWNII-UHFFFAOYSA-
EC 204-388-4
3-Amino-4-methoxy-N-phenyl-benzamide
UNII-V5Y646AW8S
NSC50647
WLN: 1OR BZ DVMR
Cambridge id 5301790
Oprea1_563744
SCHEMBL610530
DTXCID1030159
p-Anisanilide, 3-amino-(8CI)
AC8086
BBL027830
STK804189
3-AMINO-4-METHOXYBENZANILIDINE
4-methoxy-3-amino-N-phenyl-benzamide
AKOS000132022
3-amino-4 -methoxy-N-phenyl-benzamide
CS-W012775
FA00877
3-Amino-4-methoxy-N-phenylbenzamide #
AS-63529
M-40
SY016941
DB-022224
A1954
NS00004705
AB00079390-01
Q27291569
204-388-4