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Phenytoin

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Identification
Molecular formula
C15H12N2O2
CAS number
57-41-0
IUPAC name
3-amino-5,5-diphenyl-imidazolidine-2,4-dione
State
State

Phenytoin is typically in a solid state at room temperature.

Melting point (Celsius)
295.00
Melting point (Kelvin)
568.15
Boiling point (Celsius)
297.23
Boiling point (Kelvin)
570.38
General information
Molecular weight
252.27g/mol
Molar mass
252.2680g/mol
Density
1.4000g/cm3
Appearence

Phenytoin is a white, crystalline substance.

Comment on solubility

Solubility of 3-amino-5,5-diphenyl-imidazolidine-2,4-dione

3-amino-5,5-diphenyl-imidazolidine-2,4-dione displays intriguing characteristics when it comes to its solubility. This compound is generally described as:

  • Practically insoluble in water.
  • More soluble in organic solvents such as acetone, ethanol, and chloroform.

The solubility profile can be attributed to several factors:

  1. Molecular Structure: The presence of bulky phenyl groups enhances hydrophobic interactions, thus limiting its solubility in polar solvents like water.
  2. Polarity: The overall nonpolar character of the compound plays a significant role in its limited interaction with water molecules.
  3. Hydrogen Bonding: While the amino group can potentially engage in hydrogen bonding, the steric hindrance from the phenyl groups may obstruct effective solvation in aqueous solutions.

In practical applications, users can enhance solubilization by utilizing:

  • Appropriate organic solvents.
  • Adjusting the pH to create more favorable conditions for solubility.

In conclusion, while 3-amino-5,5-diphenyl-imidazolidine-2,4-dione demonstrates limited water solubility, its behavior in organic solvents presents opportunities for various applications.

Interesting facts

Interesting Facts about 3-amino-5,5-diphenyl-imidazolidine-2,4-dione

3-amino-5,5-diphenyl-imidazolidine-2,4-dione, commonly referred to as a derivative of imidazolidine, is an intriguing compound that showcases the interplay between organic synthesis and medicinal chemistry. Here are some fascinating aspects of this compound:

  • Structure and Function: This compound features a unique imidazolidine core, which is structured to include two phenyl groups and an amino substituent. This configuration contributes to its potential for biological activity.
  • Biological Relevance: Compounds of this type have been studied for their pharmaceutical applications, particularly as antioxidants. The imidazolidine framework can influence reactive oxygen species (ROS), making them valuable in drug development.
  • Versatile Synthesis: The synthesis of such compounds often involves a series of intriguing reactions. Chemists can utilize various methods while employing intermediate transformations, potentially leading to diverse products with unique properties.
  • Medicinal Properties: Research suggests that derivatives of imidazolidine, like this one, show promise in anti-inflammatory and antimicrobial activities, making them candidates for further investigation in therapeutic avenues.
  • Research Opportunities: The complex nature of this compound invites further study in formulating novel drugs. It combines essential features needed for new therapies in combating various diseases.

In summary, 3-amino-5,5-diphenyl-imidazolidine-2,4-dione exemplifies the significance of organic compounds in the development of new medicinal agents. Its unique structure opens up numerous questions and possibilities for future research in both synthetic chemistry and pharmacology.

Synonyms
1224-08-4
N-Aminodiphenylhydantoin
2,4-Imidazolidinedione, 3-amino-5,5-diphenyl-
3-Amino-5,5-diphenylhydantoin
IL 40
BRN 0262278
3-aminodiphenylhydantoin
HYDANTOIN, 3-AMINO-5,5-DIPHENYL-
DTXSID10153591
5-24-08-00401 (Beilstein Handbook Reference)
3-amino-DPH
DTXCID1076082
3-amino-5,5-diphenylimidazolidine-2,4-dione
MFCD01723004
MLS000771758
IL40
SCHEMBL4727177
CHEMBL1725368
HMS2665L22
ALBB-024837
AKOS000118502
WAY-650847
NCGC00245971-01
LS-08240
SMR000376474
EN300-13113
G22511
AB00613450-02
Z89285374