Serotonin Hydrochloride | Solubility of Things

Identification

Molecular formula

C₁₂H₁₆N₂ · 2HCl

CAS number

153-98-0

IUPAC name

(3-azaniumyl-2-pyridyl)-[2-(1H-indol-3-yl)ethyl]ammonium;dichloride

State

At room temperature, it is typically a solid, often administered in various formulations due to its solubility in aqueous solutions.

Melting point (Celsius)

167.00

Melting point (Kelvin)

440.15

Boiling point (Celsius)

275.00

Boiling point (Kelvin)

548.15

General information

Molecular weight

306.17g/mol

Molar mass

306.1670g/mol

Density

1.2000g/cm³

Appearence

This compound typically appears as a white to off-white crystalline powder. It is often supplied in its hydrochloride salt form, which is soluble in water.

Comment on solubility

Solubility of (3-azaniumyl-2-pyridyl)-[2-(1H-indol-3-yl)ethyl]ammonium;dichloride

The solubility of (3-azaniumyl-2-pyridyl)-[2-(1H-indol-3-yl)ethyl]ammonium;dichloride in various solvents is a topic of interest due to its structural complexity. This compound, characterized by its unique functional groups and charged nature, tends to exhibit different solubility behaviors:

Water Solubility: Typically, compounds with ammonium groups like this one show good solubility in water due to the ion-dipole interactions. The presence of dichloride also implies a higher degree of hydration.
Organic Solvents: Solubility in organic solvents can vary widely. Compounds with aromatic rings may find better solubility in less polar solvents due to π–π stacking interactions. However, the overall polarity of the molecule plays a crucial role.
Temperature Effects: Temperature can influence solubility positively, often increasing at higher temperatures for many compounds, facilitating better dissolution.

The combined effects of these factors suggest that while (3-azaniumyl-2-pyridyl)-[2-(1H-indol-3-yl)ethyl]ammonium;dichloride may be soluble in water, its solubility profile in organic solvents would require experimental determination. As solubility is a key property in pharmaceuticals and chemical applications, understanding it can open pathways for optimizing formulations and achieving desired biological activities.

Interesting facts

Interesting Facts about (3-azaniumyl-2-pyridyl)-[2-(1H-indol-3-yl)ethyl]ammonium; dichloride

This fascinating compound represents a unique amalgamation of pyridine and indole moieties, highlighting the versatility and complexity of organic chemistry. It is particularly notable for its potential in various fields, including medicinal chemistry and material science. Here are some intriguing aspects of this compound:

Pharmacological Potential: The presence of the indole structure is associated with many biologically active compounds, including various pharmaceuticals. Indoles are known for their role in serotonin function, which has implications for mood regulation and neurological research.
Ammonium Ion Characteristics: The (3-azaniumyl) portion indicates a quaternary ammonium ion, which is significant for its solubility properties and ability to interact with biological membranes, further enhancing its pharmacological prospects.
Structural Diversity: The combination of a pyridyl group and an indole highlights the compound's structural diversity, offering numerous sites for chemical modifications. Such adjustments can yield derivatives with enhanced biological activity or novel functionalities.
Potential as an Ionic Liquid: Given the ammonium aspect and the dichloride counterion, this compound may exhibit characteristics of ionic liquids, which are intriguing for their low vapor pressure and thermal stability, making them suitable for various applications, including green chemistry.

As chemists continue to explore such compounds, the multidimensional nature of (3-azaniumyl-2-pyridyl)-[2-(1H-indol-3-yl)ethyl]ammonium; dichloride opens new avenues for research and innovation. The ever-evolving understanding of its properties could lead to groundbreaking discoveries in drug development and material applications.