Skip to main content

granisetron hydrochloride

ADVERTISEMENT
Identification
Molecular formula
C18H24Cl2N4
CAS number
107007-99-8
IUPAC name
(3-azaniumyl-4-pyridyl)-[2-(1H-indol-3-yl)ethyl]ammonium;dichloride
State
State

Granisetron hydrochloride is generally solid at room temperature, typically found as a crystalline powder for pharmaceutical applications.

Melting point (Celsius)
132.00
Melting point (Kelvin)
405.15
Boiling point (Celsius)
150.00
Boiling point (Kelvin)
423.15
General information
Molecular weight
312.87g/mol
Molar mass
312.8710g/mol
Density
1.3700g/cm3
Appearence

Granisetron hydrochloride typically appears as a white to off-white crystalline powder. It is usually provided in a fine, crystalline form that is free-flowing and easy to handle for use in pharmaceutical formulations.

Comment on solubility

Solubility of (3-azaniumyl-4-pyridyl)-[2-(1H-indol-3-yl)ethyl]ammonium;dichloride

The compound (3-azaniumyl-4-pyridyl)-[2-(1H-indol-3-yl)ethyl]ammonium;dichloride is an intriguing example of a complex organic salt. Its solubility behavior can be largely attributed to its structural features and the nature of the dichloride salt form.

Key points regarding its solubility include:

  • Polar Nature: Due to the presence of the ammonium group and chlorine ions, this compound shows a high degree of polarity, which typically enhances solubility in polar solvents.
  • Water Solubility: Many salts, especially those containing ammonium groups, are often soluble in water, leading to the expectation that this compound exhibits good solubility in aqueous environments.
  • Solvent Dependence: The solubility may vary significantly with different solvents. While it is likely soluble in water, less polar solvents may show diminished solubility.
  • Temperature Influence: Like many ionic compounds, increasing the temperature can also affect solubility, often increasing it, which is a factor worth considering in experimental applications.

In short, the solubility characteristics of (3-azaniumyl-4-pyridyl)-[2-(1H-indol-3-yl)ethyl]ammonium;dichloride are largely favorable in polar solvents such as water, making it accessible for various chemical and biological applications. Its unique polar structure coupled with salt formation presents a fascinating case in the study of solubility in chemical compounds.

Interesting facts

Interesting Facts about (3-azaniumyl-4-pyridyl)-[2-(1H-indol-3-yl)ethyl]ammonium;dichloride

This intriguing compound, often referred to in the scientific community for its unique structural features, showcases a fascinating combination of organic functional groups that contribute to its potential applications in various fields. Here are a few compelling aspects:

  • Complex Structure: The compound is derived from an indole core, which is a structure frequently found in many biologically active molecules, including neurotransmitters and pharmaceuticals. This highlights its possible significance in medicinal chemistry.
  • Dichloride Salt: As a salt, the dichloride form can enhance its solubility and stability, making it a useful candidate for experimental studies and potential drug formulations.
  • Biological Activity: Compounds with indole moieties are known for their diverse biological activities, including anti-cancer, anti-inflammatory, and antimicrobial properties, opening the door for research on new therapeutic agents.
  • Rotational Flexibility: The ethyl bridge connecting the indole and pyridine structures may introduce a degree of rotational flexibility. This could impact the compound's interaction with biological targets and affect its efficacy.
  • Potential Applications: Given its unique properties, this compound could be explored for applications in drug design, synthetic chemistry, and materials science. It might serve as a precursor for creating more complex molecules.

Chemists are always excited about compounds like this, which not only illustrate the elegance of molecular architecture but also hold the promise of contributing significantly to advancements in health and materials technology. The interplay of the azaniumyl and pyridyl groups in this compound further invites a closer look to decipher its interaction mechanisms and effects.