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3-(Benzenesulfonyl)-1-phenylisothiourea

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Identification
Molecular formula
C13H12N2O2S2
CAS number
57045-64-6
IUPAC name
3-(benzenesulfonyl)-1-phenyl-isothiourea
State
State
At room temperature, 3-(benzenesulfonyl)-1-phenylisothiourea is a solid.
Melting point (Celsius)
210.00
Melting point (Kelvin)
483.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
274.37g/mol
Molar mass
274.3360g/mol
Density
1.3400g/cm3
Appearence

3-(Benzenesulfonyl)-1-phenylisothiourea typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 3-(benzenesulfonyl)-1-phenyl-isothiourea

The solubility of 3-(benzenesulfonyl)-1-phenyl-isothiourea in various solvents presents an intriguing profile. This compound exhibits a unique behavior that can be influenced by several factors:

  • Polarity of the solvent: The solubility is generally higher in polar solvents due to the ability of the sulfonyl group to engage in strong dipole-dipole interactions.
  • Temperature: An increase in temperature typically enhances solubility for most organic compounds, including isothioureas, potentially leading to greater solute-solvent interactions.
  • pH of the solution: Since isothioureas can participate in protonation and deprotonation, their solubility may vary significantly depending on the pH level of the solvent.

Moreover, it is noteworthy that 3-(benzenesulfonyl)-1-phenyl-isothiourea tends to have limited solubility in non-polar solvents, which may suggest a need for *careful selection* of solvents when preparing solutions or conducting reactions. As stated, "the solubility characteristics of a compound not only define its potential applications but also its reactivity in various environments." Thus, understanding the solubility behavior of this compound can offer valuable insights into its chemical properties and reactions.

In summary, when working with 3-(benzenesulfonyl)-1-phenyl-isothiourea, consider the solvent choice, temperature, and pH, as these factors are crucial for optimizing its solubility and functionality in practical applications.

Interesting facts

Interesting Facts about 3-(Benzenesulfonyl)-1-phenyl-isothiourea

3-(Benzenesulfonyl)-1-phenyl-isothiourea is a fascinating compound notable for its diverse applications and unique structural characteristics. Here are some captivating aspects:

  • Structural Features: This compound contains an isothiourea moiety, which is often characterized by a sulfur atom bonded to both a nitrogen atom and a carbon atom, giving it distinct chemical properties.
  • Biological Relevance: Compounds like 3-(benzenesulfonyl)-1-phenyl-isothiourea have been studied for their potential biological activities. They display interesting pharmacological profiles which may contribute to therapeutic applications.
  • Synthesis: The synthesis of this compound can involve methods that typically incorporate sulfonation reactions, making it a good example for students learning organic synthesis techniques.
  • Research Applications: This compound has gained attention in chemical research, particularly in the study of enzyme inhibitors, which are crucial in drug development processes.

A notable quote from a renowned chemist reminds us of the importance of functionalized thioureas in organic chemistry: "The versatility of thiourea derivatives in various chemical transformations is truly remarkable." As we explore the world of isothioureas, compounds like 3-(benzenesulfonyl)-1-phenyl-isothiourea exemplify the intricate connections between structure and function in chemical compounds.

In summary, the exploration of this compound not only enriches our understanding of organic chemistry but also highlights the potential implications in medicinal chemistry and drug design.