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Diphenhydramine

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Identification
Molecular formula
C17H21NO
CAS number
58-73-1
IUPAC name
3-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane
State
State
Diphenhydramine is commonly found in a solid state at room temperature. Its physical form allows it to be processed into various pharmaceutical forms, most notably for use as an antihistamine and sedative.
Melting point (Celsius)
168.00
Melting point (Kelvin)
441.15
Boiling point (Celsius)
153.00
Boiling point (Kelvin)
426.15
General information
Molecular weight
255.36g/mol
Molar mass
255.3640g/mol
Density
1.0060g/cm3
Appearence

Diphenhydramine is typically found as a white crystalline powder. It is often formulated in various solid dosage forms such as tablets and capsules, as well as in liquid formulations for easier administration.

Comment on solubility

Solubility of 3-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane (C17H21NO)

The solubility of 3-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane can be influenced by several factors, making it a compound of interest in various chemical applications. Here are some key points to consider:

  • Solvent Polarity: This compound is likely to exhibit varying solubility in polar and non-polar solvents. In general, organic compounds with significant hydrophobic characteristics, like 3-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane, may dissolve better in non-polar solvents.
  • Temperature Influence: Increased temperature usually enhances solubility. As temperature rises, molecular motion increases, allowing the solute molecules to overcome intermolecular forces and dissolve more readily.
  • Functional Groups: The presence of hydroxyl (-OH) and amine (-NH) functional groups in the compound can potentially increase solubility in polar solvents, such as alcohols and water, through hydrogen bonding.
  • Crystal Structure: The arrangement of atoms in the solid state can affect solubility. Well-ordered crystal lattices may exhibit lower solubility compared to compounds with less crystalline structure, facilitating easier dissolution.

In summary, while the solubility of 3-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane may not be extensively documented, one can hypothesize that its solubility behavior depends on the interplay of its molecular characteristics and the solvent environment. Always consider the context of application when evaluating its solubility properties.

Interesting facts

Interesting Facts about 3-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane

3-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane is a fascinating compound belonging to a class of molecules known as bicyclic amines. Here are some notable insights into its structure and potential applications:

  • Bicyclic Structure: The compound features a unique bicyclic structure, which contributes to its varied chemical behaviors and interactions.
  • Pharmacological Potential: Compounds like this one are often studied for their potential as pharmaceuticals. They may interact with neurotransmitter systems, particularly in ways that could impact mood and cognition.
  • Synthesis: The synthesis of such compounds often requires advanced organic chemistry techniques, including multi-step reactions that can lead to interesting methodological approaches.
  • Analogous Compounds: This compound may share structural similarities with known drugs, making it a valuable target for research in developing new therapeutic agents.

As a scientist or chemistry student, exploring the functionalities of this compound can lead to exciting discoveries in the field of medicinal chemistry and pharmacognosy. The study of its interactions with biological systems is an area ripe for investigation, providing insights that could lead to novel treatments.

In summary, 3-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane exemplifies the intricate world of organic compounds, inviting further research into its properties and potential benefits.

Synonyms
3-(diphenylmethoxy)-8-methyl-8-azabicyclo[3.2.1]octane
Pseudobenztropine
3-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane
CHEMBL116590
13050-78-7
80677-48-1
8-Azabicyclo[3.2.1]octane,3-(diphenylmethoxy)-8-methyl-, hydrobromide (1:1)
802597-90-6
Benzotropine
8-Azabicyclo[3.2.1]octane, 3-(diphenylmethoxy)-8-methyl-, endo-
(3-exo)-3-(Diphenylmethoxy)-8-methyl-8-azabicyclo[3.2.1]octane; 3ss-(Diphenylmethoxy)-1aH,5aH-tropane
Cogentin (Salt/Mix)
Spectrum_000078
Spectrum2_000106
Spectrum3_000316
Spectrum4_000251
Spectrum5_000884
1.alpha.H,5.alpha.H-Tropane, 3.alpha.-(diphenylmethoxy)-
NCIOpen2_008292
Lopac0_000194
Oprea1_754774
SCHEMBL35389
BSPBio_001912
KBioGR_000682
KBioSS_000478
DivK1c_000523
SPBio_000092
BDBM86698
CHEBI:94353
KBio1_000523
KBio2_000478
KBio2_003046
KBio2_005614
KBio3_001412
DTXSID80859139
NINDS_000523
CHB59790
HY-B0520
NSC_2344
BBL033607
STK931885
AKOS005661487
CCG-204289
SDCCGSBI-0050182.P006
IDI1_000523
NCGC00162087-01
NCGC00162087-02
NCGC00162087-03
NCGC00507752-01
CAS_132-17-2
NCI60_003960
SBI-0050182.P004
CS-0009494
EN300-51100
L000767
3-diphenylmethoxy-8-methyl-8-azabicyclo[3.2.1]octane
Q27166187
3.alpha.-(Diphenylmethoxy)-1.alpha.H,5.alpha.H-tropane
3-(diphenylmethyl)oxy-8-methyl-8-azabicyclo[3.2.1]octane
Benzhydryl 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ether #