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3-Benzoylindole-5-carbonitrile

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Identification
Molecular formula
C16H10N2O
CAS number
885519-24-0
IUPAC name
3-benzoyl-1H-indole-5-carbonitrile
State
State

At room temperature, 3-Benzoyl-1H-indole-5-carbonitrile is a solid compound. Its crystalline nature allows it to be handled easily in the laboratory setting, typically stored under dry conditions to maintain stability.

Melting point (Celsius)
156.00
Melting point (Kelvin)
429.15
Boiling point (Celsius)
74.00
Boiling point (Kelvin)
347.15
General information
Molecular weight
236.26g/mol
Molar mass
236.1230g/mol
Density
1.2661g/cm3
Appearence

3-Benzoyl-1H-indole-5-carbonitrile generally appears as a crystalline solid. It tends to be off-white to light brown in color, depending on the level of purity and any impurities present. The appearance may vary based on synthesis and storage conditions.

Comment on solubility

Solubility of 3-benzoyl-1H-indole-5-carbonitrile

The solubility of 3-benzoyl-1H-indole-5-carbonitrile in various solvents can be quite interesting to explore due to its unique chemical structure. This compound is known for its relatively low solubility in water, a characteristic common among many indole derivatives. Here’s a breakdown of its solubility characteristics:

  • Organic Solvents: It tends to dissolve well in organic solvents such as ethyl acetate, dimethyl sulfoxide (DMSO), and acetone.
  • Polar Solvents: While it shows limited solubility in polar solvents like methanol and ethanol, the solubility can depend significantly on temperature and concentration.
  • Hydrophobic Nature: The presence of the benzoyl and carbonitrile groups contributes to its hydrophobic nature, further limiting the solubility in aqueous environments.

It is important to note that the solubility can be influenced by factors such as pH, temperature, and the presence of other solutes. As such, one might say, "Solubility is not just about the chemical structure; it is a dance with the environment." Understanding the solubility helps in determining how this compound can be utilized in various applications, particularly in pharmaceutical formulations.

Interesting facts

Interesting Facts about 3-benzoyl-1H-indole-5-carbonitrile

3-benzoyl-1H-indole-5-carbonitrile is a fascinating compound that belongs to the indole family, known for its extensive applications in various fields of science and industry. Here are some interesting facets of this compound:

  • Pharmaceutical Applications: The indole structure is pivotal in medicinal chemistry, with many drugs featuring this moiety. Compounds like 3-benzoyl-1H-indole-5-carbonitrile have potential uses in antidepressants, anticancer agents, and anti-inflammatory drugs.
  • Research Significance: Studies have suggested that such compounds could be explored for their role in targeting specific biological pathways, making them a rich area for research in drug discovery.
  • Synthetic Pathways: The synthesis of 3-benzoyl-1H-indole-5-carbonitrile is an example of how chemists utilize multistep synthetic routes to create complex structures, often involving novel methodologies to enhance yield and reduce by-products.
  • Variety of Properties: This compound is known to exhibit interesting chemical properties including electronic and optical characteristics that could be exploited in organic electronics or materials science.
  • Indole Derivatives: Indoles and their derivatives have a rich history in natural products; for instance, many alkaloids contain indole motifs, making this compound relevant to the study of natural sciences.

Overall, 3-benzoyl-1H-indole-5-carbonitrile serves as a compelling subject of study, illustrating the vast potential of indole derivatives in advancing both fundamental and applied sciences. As chemistry continues to progress, compounds such as this will undoubtedly play a critical role in developing innovative solutions for modern challenges.

Synonyms
5-Cyanoindolyl-3-phenylketone
INDOLE-5-CARBONITRILE, 3-BENZOYL-
3-Benzoylindole-5-carbonitrile
17380-22-2
DTXSID80169664
DTXCID1092155