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Coumarin 3-carboxylic acid

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Identification
Molecular formula
C16H10O3
CAS number
19378-76-4
IUPAC name
3-benzoylchromen-2-one
State
State

At room temperature, 3-benzoylchromen-2-one is in a solid state.

Melting point (Celsius)
176.00
Melting point (Kelvin)
449.15
Boiling point (Celsius)
429.10
Boiling point (Kelvin)
702.25
General information
Molecular weight
250.25g/mol
Molar mass
250.2460g/mol
Density
1.3700g/cm3
Appearence

3-Benzoylchromen-2-one is typically found as a crystalline solid. Its appearance can be described as off-white to pale yellow depending on purity and handling.

Comment on solubility

Solubility of 3-benzoylchromen-2-one

3-benzoylchromen-2-one, known for its fascinating chemical structure, exhibits a variable solubility profile depending on the solvent used. This unique compound is generally characterized by:

  • Moderate Solubility in Organic Solvents: It dissolves well in organic solvents such as ethanol, methanol, and chloroform.
  • Poor Solubility in Water: The compound demonstrates limited solubility in water, which is typical for many organic molecules with aromatic characteristics.
  • Dependence on pH: The solubility can also be influenced by the pH of the medium. In more acidic or basic solutions, the solubility might either increase or decrease, affecting its biological activity.

In conclusion, the solubility of 3-benzoylchromen-2-one can be summarized as follows: it is primarily soluble in non-polar and medium polar solvents, while exhibiting limited solubility in polar solvents like water. Understanding these solubility characteristics is crucial for its application in various chemical and pharmaceutical processes.

Interesting facts

Interesting Facts about 3-benzoylchromen-2-one

3-benzoylchromen-2-one, a noteworthy compound in the realm of organic chemistry, is celebrated for its distinctive structure and diverse applications. Here are some engaging insights:

  • Structural Significance: This compound features a chromenone structure, merging the aromatic properties of the benzoyl group with a chromene backbone. This unique arrangement allows for interesting chemical behavior and interactions.
  • Biological Activities: Studies suggest that 3-benzoylchromen-2-one exhibits a range of biological activities. It has shown potential as an anti-inflammatory and antioxidant agent, making it a candidate for pharmaceutical exploration.
  • Fluorescent Properties: The compound can exhibit fluorescence under certain conditions, which makes it useful in various fields such as **biochemistry** and **analytical chemistry**. Researchers often leverage this property for detection methods.
  • Derivative Synthesis: Due to its reactive functional groups, 3-benzoylchromen-2-one serves as a versatile building block for synthesizing more complex organic compounds, such as derivatives that can enhance its biological activities.
  • Natural Occurrence: Similar structures to 3-benzoylchromen-2-one can be found in several natural products, where they play roles in plant defense mechanisms and secondary metabolite production.

In summary, 3-benzoylchromen-2-one showcases a balance of structural complexity and functional diversity, making it a rich subject for research in organic and medicinal chemistry. As scholars and scientists delve deeper into its properties, the full potential of this compound continues to unfold.

Synonyms
3-Benzoylcoumarin
COUMARIN, 3-BENZOYL-
2H-1-Benzopyran-2-one, 3-benzoyl-
3-Benzoyl-2H-1-benzopyran-2-one
XF9P5UO8IN
NSC 11862
BRN 0190875
UNII-XF9P5UO8IN
NSC-11862
DTXSID6075144
5-17-11-00557 (Beilstein Handbook Reference)
DTXCID1035866
2H-1-Benzopyran-2-one, 3-benzoyl-(9CI)
1846-74-8
3-benzoyl-2H-chromen-2-one
3-benzoylchromen-2-one
3-Benzoyl-chromen-2-one
NSC11862
ChemDiv3_012376
Oprea1_857667
SCHEMBL51507
MLS001201222
CHEMBL591522
HMS1508C12
HMS2850G06
BAA84674
MFCD00233579
STL145336
3-(phenylcarbonyl)-2H-chromen-2-one
AKOS002087789
NCGC00245922-01
SMR000564143
DB-365952
CS-0359755
EU-0027162
SR-01000143218
SR-01000143218-1
BRD-K16706387-001-01-0
F0916-3926