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Cotinine

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Identification
Molecular formula
C10H12N2O
CAS number
486-56-6
IUPAC name
3-benzyl-1,8,8-trimethyl-3-azabicyclo[3.2.1]octane
State
State

At room temperature, cotinine is typically in a solid state, appearing as white crystals.

Melting point (Celsius)
44.00
Melting point (Kelvin)
317.15
Boiling point (Celsius)
344.80
Boiling point (Kelvin)
618.00
General information
Molecular weight
176.26g/mol
Molar mass
176.2590g/mol
Density
1.0056g/cm3
Appearence

Cotinine is typically found as a white crystalline solid. It has a crystalline structure that is characteristic of many alkaloids.

Comment on solubility

Solubility of 3-benzyl-1,8,8-trimethyl-3-azabicyclo[3.2.1]octane

The solubility of 3-benzyl-1,8,8-trimethyl-3-azabicyclo[3.2.1]octane can be characterized by its unique structural properties. This compound belongs to a class of bicyclic amines that often exhibit specific solubility behavior in various solvents. Here are some key points regarding its solubility:

  • Organic Solvents: Typically, compounds like 3-benzyl-1,8,8-trimethyl-3-azabicyclo[3.2.1]octane are soluble in organic solvents such as dichloromethane, chloroform, and ethanol. The presence of both alkyl groups and aromatic systems tends to enhance solubility.
  • Polarity Considerations: Given its aromatic characteristics, this compound may exhibit greater solubility in non-polar or weakly polar solvents compared to highly polar solvents such as water.
  • Temperature Effects: As with many organic compounds, solubility can increase with temperature. Thus, heating the solution can facilitate better dissolution in organic solvents.

In summary, while 3-benzyl-1,8,8-trimethyl-3-azabicyclo[3.2.1]octane is likely to be soluble in a range of organic solvents, its overall solubility in water is expected to be low. Understanding the solubility profile of this compound is crucial for applications in chemical synthesis and formulation.

Interesting facts

Interesting Facts about 3-benzyl-1,8,8-trimethyl-3-azabicyclo[3.2.1]octane

The compound 3-benzyl-1,8,8-trimethyl-3-azabicyclo[3.2.1]octane is a fascinating member of the bicyclic alkaloid family. This unique structure not only showcases the creativity of nature's architecture but also opens doors for various applications in synthetic organic chemistry.

Key Features:

  • Bicyclic Structure: Featuring a bicyclic framework, it possesses both nitrogen and carbon atoms in its ring system, which contributes to its distinctive properties.
  • Combining Aromaticity: The presence of a benzyl group introduces aromatic characteristics, which can enhance the reactivity and stability of the compound.
  • Potential Biological Activity: Compounds in the azabicyclo family often exhibit interesting biological activities, making them valuable in pharmaceuticals and medicinal chemistry.
  • Synthetic Pathways: Its complex structure poses intriguing challenges in synthesis, often requiring innovative strategies and methods in organic synthesis to create it.

More than just a chemical entity, 3-benzyl-1,8,8-trimethyl-3-azabicyclo[3.2.1]octane might also serve as a template for developing new compounds with improved properties. In the words of chemists, “Every compound tells a story,” and in this case, the story is rich with potential.

As a compound that blurs the line between organic chemistry and pharmacology, 3-benzyl-1,8,8-trimethyl-3-azabicyclo[3.2.1]octane is a reminder of the endless possibilities within the realm of molecular design and synthesis.