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3-Benzyl-1H-indole-5-carbonitrile

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Identification
Molecular formula
C16H12N2
CAS number
74978-11-7
IUPAC name
3-benzyl-1H-indole-5-carbonitrile
State
State

At room temperature, 3-Benzyl-1H-indole-5-carbonitrile is typically a solid. It is relatively stable under standard conditions, but as with many organic compounds, it should be handled with care to avoid decomposition or reaction with other chemicals.

Melting point (Celsius)
158.00
Melting point (Kelvin)
431.00
Boiling point (Celsius)
450.00
Boiling point (Kelvin)
723.00
General information
Molecular weight
232.28g/mol
Molar mass
232.2750g/mol
Density
1.1200g/cm3
Appearence

3-Benzyl-1H-indole-5-carbonitrile is typically found in a crystalline solid form. Its exact color can vary depending on the specific sample, but it is often off-white or pale yellow in appearance.

Comment on solubility

Solubility of 3-benzyl-1H-indole-5-carbonitrile

3-benzyl-1H-indole-5-carbonitrile is a compound known for its intriguing solubility characteristics. Its solubility can be influenced by several factors, making it a subject of interest in both research and application. Here are some key points to consider:

  • Polar vs. Nonpolar Solvents: This compound is more likely to dissolve in nonpolar solvents due to its hydrophobic nature. Typical nonpolar solvents include toluene and dichloromethane.
  • Temperature Dependency: Like many organic compounds, the solubility of 3-benzyl-1H-indole-5-carbonitrile is temperature-dependent. Increased temperatures typically enhance solubility.
  • Concentration Effects: At higher concentrations, the solubility may exhibit unique behaviors, possibly leading to precipitation or crystallization if it exceeds saturation limits.
  • Hydrophobic Interactions: The presence of the benzyl group can influence solubility by contributing to hydrophobic interactions that affect how the compound interacts with its solvent environment.

In conclusion, the solubility of 3-benzyl-1H-indole-5-carbonitrile showcases the complex interplay between structure and solvent interactions, reflecting the need for careful consideration in experimental design. Understanding this solubility profile is essential for its practical applications in various fields.

Interesting facts

Interesting Facts about 3-benzyl-1H-indole-5-carbonitrile

3-benzyl-1H-indole-5-carbonitrile is a fascinating compound that belongs to the indole class of organic compounds, which are known for their diverse biological activities.

Applications in Research

This compound has drawn interest in various fields of research due to its potential applications, including:

  • Pharmaceutical Development: Researchers are exploring its properties for new drug formulations.
  • Biological Activity: It shows promise in exhibiting antifungal and antibacterial properties, making it relevant for medicinal chemistry.
  • Material Science: Its unique structure can lead to the development of novel materials with specific properties.

Chemical Structure and Significance

The structural features of 3-benzyl-1H-indole-5-carbonitrile contribute significantly to its chemical behavior:

  • Indole Ring: The indole moiety is crucial for numerous biological interactions, thanks to its ability to mimic biological molecules.
  • Benzyl Substituent: The presence of a benzyl group enhances the lipophilicity of the compound, potentially improving its cell permeability.
  • Carbonitrile Functional Group: The carbonitrile group plays a pivotal role in chemical reactivity, making it a vital point of interest in synthetic chemistry.

Insights from the Laboratory

In the laboratory setting, chemists are continuously exploring 3-benzyl-1H-indole-5-carbonitrile for:

  • Synthesis Techniques: New synthetic methods for efficient production are being developed, offering insights into reaction mechanisms.
  • Modifications: The compound serves as a scaffold for producing derivatives that may exhibit improved activity or selectivity.
  • Bioassays: Researchers conduct bioassays to evaluate its efficacy against various pathogens, pushing the boundaries of its potential uses.

With all of these characteristics, it's no wonder that 3-benzyl-1H-indole-5-carbonitrile remains a subject of growing research interest. As scientists delve deeper into its properties, we can expect to uncover even more exciting applications and insights!

Synonyms
17380-31-3
3-Benzyl-5-cyanoindole
INDOLE-5-CARBONITRILE, 3-BENZYL-
3-Benzylindole-5-carbonitrile
DTXSID00169666
DTXCID1092157
3-benzyl-1H-indole-5-carbonitrile
SCHEMBL5899817