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3-Benzyl-3-phenylazetidin-2-one

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Identification
Molecular formula
C16H15NO
CAS number
14482-47-0
IUPAC name
3-benzyl-3-phenyl-azetidin-2-one
State
State

At room temperature, 3-Benzyl-3-phenylazetidin-2-one is typically found in a solid state, often used in the synthesis of various pharmaceutical compounds due to its stability and reactivity.

Melting point (Celsius)
102.00
Melting point (Kelvin)
375.15
Boiling point (Celsius)
455.50
Boiling point (Kelvin)
728.70
General information
Molecular weight
251.31g/mol
Molar mass
251.3060g/mol
Density
1.2080g/cm3
Appearence

3-Benzyl-3-phenylazetidin-2-one typically appears as a white to off-white crystalline powder. Its crystalline property is often leveraged in various synthesis applications.

Comment on solubility

Solubility of 3-benzyl-3-phenyl-azetidin-2-one

The compound 3-benzyl-3-phenyl-azetidin-2-one is characterized by its unique structure, which influences its solubility properties in various solvents. Understanding the solubility of this compound is essential for its application in different fields. Here are some key points regarding its solubility:

  • Solvent Polarity: This compound tends to dissolve better in non-polar to slightly polar solvents, such as ethanol, tetrahydrofuran (THF), and chloroform.
  • Water Solubility: 3-benzyl-3-phenyl-azetidin-2-one exhibits low solubility in water, which is common for organic compounds with large aromatic groups.
  • Temperature Influence: Increasing the temperature generally enhances solubility, facilitating the dissolution process in suitable organic solvents.

In summary, when considering the use of 3-benzyl-3-phenyl-azetidin-2-one, one should choose the solvent carefully to ensure optimal solubility and reactivity. Understanding the solubility characteristics of this compound is crucial for its effective application in synthesis and potential pharmaceutical uses.

Interesting facts

Interesting Facts about 3-benzyl-3-phenyl-azetidin-2-one

3-benzyl-3-phenyl-azetidin-2-one is a fascinating compound that belongs to the class of azetidinones, which are four-membered cyclic amides. Here are some intriguing aspects of this unique compound:

  • Structural Significance: The presence of both benzyl and phenyl groups in its structure contributes to the compound's chemical behavior and reactivity, making it an interesting subject for studies in organic synthesis.
  • Pharmacological Potential: Compounds similar to azetidinones have demonstrated various biological activities, including antibacterial and anti-inflammatory properties. This places 3-benzyl-3-phenyl-azetidin-2-one in a noteworthy position for research in pharmaceutical applications.
  • Synthesis Versatility: Its synthesis often involves functional group transformations, allowing chemists to explore various reaction pathways and develop innovative methods for producing related compounds.
  • Applications in Material Science: Some azetidinones, including this compound, may have potential uses in the development of polymers and other materials, which further expands their significance in the field of chemistry.

As a chemistry student or professional, you might find it particularly interesting to explore how subtle changes in the structure of such compounds can lead to vastly different properties and applications. The journey from theoretical concepts to practical implementations in medicinal chemistry is both challenging and exhilarating.

"Discovery consists of seeing what everybody has seen and thinking what nobody has thought." — Albert Szent-Györgyi. This quote perfectly encapsulates the innovative spirit required to delve into the depths of compounds like 3-benzyl-3-phenyl-azetidin-2-one.

Synonyms
3-benzyl-3-phenylazetidin-2-one
17197-61-4
L 1733
3-Benzyl-3-phenyl-2-azetidinone
BRN 0181804
3-Fenil-3-benzil-2-azetidinone [Italian]
2-AZETIDINONE, 3-BENZYL-3-PHENYL-
3-Fenil-3-benzil-2-azetidinone
4-21-00-04288 (Beilstein Handbook Reference)
DTXSID00938076
3-Benzyl-3-phenyl-3,4-dihydroazet-2-ol