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3-Benzyl-3-phenylazetidine

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Identification
Molecular formula
C16H17N
CAS number
78180-55-3
IUPAC name
3-benzyl-3-phenyl-azetidine
State
State

At room temperature, 3-Benzyl-3-phenylazetidine is generally a liquid, owing to its relatively low melting point.

Melting point (Celsius)
32.00
Melting point (Kelvin)
305.15
Boiling point (Celsius)
332.00
Boiling point (Kelvin)
605.15
General information
Molecular weight
223.32g/mol
Molar mass
223.3320g/mol
Density
1.0600g/cm3
Appearence

3-Benzyl-3-phenylazetidine typically appears as a colorless to pale yellow liquid. It may also be encountered as a clear solution when dissolved in organic solvents. The compound is characterized by its aromatic hydrocarbon scents due to the presence of benzyl and phenyl groups.

Comment on solubility

Solubility of 3-benzyl-3-phenyl-azetidine

3-benzyl-3-phenyl-azetidine is a fascinating compound with unique solubility characteristics. Understanding these characteristics is essential for practical applications and research purposes.

General Solubility Characteristics

  • Solvent Type: This compound primarily exhibits moderate solubility in organic solvents due to its hydrophobic phenyl and benzyl groups.
  • Polar vs. Non-polar: It tends to be less soluble in polar solvents (like water) and is more soluble in non-polar solvents (like hexane or toluene).

Factors Affecting Solubility

The solubility of 3-benzyl-3-phenyl-azetidine can be influenced by several factors:

  • Temperature: Generally, an increase in temperature can enhance solubility in most solvents.
  • Molecular Interactions: Intermolecular forces, such as van der Waals interactions, play a significant role in determining solubility.
  • Concentration: The solubility limit may vary with the concentration of the compound in the solvent.

In summary, while 3-benzyl-3-phenyl-azetidine shows promising solubility in various organic solvents, its limited solubility in aqueous solutions highlights the necessity to choose the appropriate solvent for experiments and applications. Researchers and practitioners should consider these factors to maximize efficacy in their work.

Interesting facts

Interesting Facts about 3-Benzyl-3-phenyl-azetidine

3-Benzyl-3-phenyl-azetidine is a fascinating compound that belongs to the class of azetidines, which are four-membered cyclic amines. Here are some captivating aspects of this compound:

  • Cyclic Structure: Azetidines are known for their unique ring structure. With four carbon atoms, the azetidine ring is one of the smallest cyclic amines and possesses interesting torsional strain properties that can influence its chemical reactivity.
  • Pharmacological Potential: Compounds like 3-benzyl-3-phenyl-azetidine have garnered attention in medicinal chemistry. The azetidine core has been explored for its potential use in designing drug candidates and biological probes due to its effective binding tendencies with biological macromolecules.
  • Synthetic Versatility: The presence of the benzyl and phenyl substituents allows for a variety of synthetic modifications. This compound can be employed as a starting material for synthesizing more complex molecules, making it a valuable intermediate in organic synthesis.
  • Application in Materials Science: Beyond pharmaceuticals, azetidines like this one may find applications in developing new materials, particularly in the realm of polymers and specialty chemicals, where their structural features can impart desirable properties.

In conclusion, 3-benzyl-3-phenyl-azetidine is not only an intriguing compound due to its structural characteristics but also holds promise in various fields including medicinal chemistry and materials science. As research continues, it’s exciting to think about the possibilities that this compound may unveil.

Synonyms
3-Benzyl-3-phenylazetidine
7215-25-0
AZETIDINE, 3-BENZYL-3-PHENYL-
L 2024
BRN 0165338
DTXSID90222491
4-20-00-03941 (Beilstein Handbook Reference)
DTXCID90144982
3-Phenyl-3-(phenylmethyl)azetidine
Azetidine, 3-phenyl-3-(phenylmethyl)-
AKOS017398263
DB-315565
EN300-252653