Interesting facts
Interesting Facts about 3-Benzyl-6-chloro-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide
This fascinating compound belongs to a class of heterocyclic compounds featuring both benzothiadiazine and sulfonamide functionalities, making it a prime subject for research in medicinal chemistry. Here are several notable aspects:
- Pharmaceutical Applications: Compounds like this one exhibit potential therapeutic properties, particularly as antihypertensive agents, which can assist in lowering blood pressure by promoting vasodilation.
- Mechanism of Action: The sulfonamide moiety present in the compound can interfere with the function of enzymes that rely on sulfonamides, highlighting the significance of structure in determining reactivity and biological activity.
- Synthesis Challenges: Due to the complex structure that includes multiple functional groups and cyclic components, synthesis can be challenging. This requires advanced techniques such as multistep synthesis and careful condition management to avoid unwanted byproducts.
- Research Interest: As researchers continue to explore this compound, there is strong interest in modifying its structure to enhance its efficacy or reduce potential side effects. Structural modifications can lead to the discovery of novel derivatives with improved pharmacological profiles.
- Interdisciplinary Connections: The study of this compound often bridges several fields such as organic chemistry, medicinal chemistry, and pharmacology, encouraging collaboration among scientists from different backgrounds.
In conclusion, 3-benzyl-6-chloro-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide serves as an excellent representation of the intricate interactions between structure and function in chemistry. As scientists delve deeper into its properties and applications, the potential for discovering new therapeutic agents continues to expand, making it an exciting compound in the realm of medicinal research.
Synonyms
benzylhydrochlorothiazide
1824-50-6
Behyd
Benzylhydrochlorothiazide [JAN]
NSC 263220
Benzylhydrochlorthiazide
NSC263220
2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-(phenylmethyl)-, 1,1-dioxide
NSC-263220
UNII-176437APQH
SU 6227
BRN 0631362
Behyd (TN)
MLS000756597
DTXSID1045114
176437APQH
Benzylhydrochlorothiazide (JAN)
DTXCID9025114
CHEBI:31269
BENZYLHYDROCHLOROTHIAZIDE [MI]
2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3-benzyl-6-chloro-3,4-dihydro-, 1,1-dioxide
3-Benzyl-3,4-dihydro-6-chlor-2H, 1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
3-benzyl-6-chloro-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide
6-Chloro-3,4-dihydro-3-(phenylmethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
BENZYLHYDROCHLOROTHIAZIDE [MART.]
BENZYLHYDROCHLOROTHIAZIDE [WHO-DD]
3-benzyl-6-chloro-1,1-dioxo-3,4-dihydro-2H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide
BENZYLHYDROCHLOROTHIAZIDE (MART.)
SMR000528814
3-benzyl-6-chloro-1,1-dioxo-3,4-dihydro-2H-1$l^(6),2,4-benzothiadiazine-7-sulfonamide
BHCTh
Oprea1_516430
SCHEMBL49671
3-benzyl-6-chloro-1,1-dioxo-3,4-dihydro-2H-1
MLS006010795
CHEMBL1562084
BWSSMIJUDVUASQ-UHFFFAOYSA-N
HMS2873E13
Su-6227
KXB02405
Tox21_110053
AKOS030254381
FB18383
3-benzyl-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
6-Chloro-3,4-dihydro-3-(phenylmethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide
NCGC00014617-01
NCI60_002101
CAS-1824-50-6
D01246
SBI-0055225.0001
BRD-A70220996-001-06-9
Q27114252
2H-1,4-Benzothiadiazine-7-sulfonamide, 3-benzyl-6-chloro-3,4-dihydro-, 1,1-dioxide
2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3-benzyl-6-chloro-3,4-dihydro-, 1,1-dioxide (8CI)
2H-1,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-(phenylmethyl)-, 1,1-dioxide
6-Chloro-3,4-dihydro-3-(phenylmethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide;Benclortriazide;Benzclortriazide
96782-98-8
Solubility of 3-benzyl-6-chloro-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide
The solubility of 3-benzyl-6-chloro-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide (C14H11ClN2NaO4S2) can be quite specific. Here are some key points to consider:
In summary, the solubility characteristics of this compound are influenced by its ionic nature, polar functional groups, and environmental conditions, making it essential to test and confirm solubility in various solvents under appropriate conditions.