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Alprazolam

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Identification
Molecular formula
C19H27N3
CAS number
28981-97-7
IUPAC name
3-benzyl-9-[2-(1-piperidyl)propyl]-3,9-diazabicyclo[3.3.1]nonane
State
State

It is typically a solid at room temperature, most commonly encountered as tablets or pills in medical contexts.

Melting point (Celsius)
228.00
Melting point (Kelvin)
501.15
Boiling point (Celsius)
315.00
Boiling point (Kelvin)
588.15
General information
Molecular weight
384.59g/mol
Molar mass
384.5880g/mol
Density
1.1500g/cm3
Appearence

Alprazolam is a white crystalline powder and is typically in solid form. It is tasteless and is commonly found in tablet form for pharmaceutical uses.

Comment on solubility

Solubility of 3-benzyl-9-[2-(1-piperidyl)propyl]-3,9-diazabicyclo[3.3.1]nonane

The solubility of 3-benzyl-9-[2-(1-piperidyl)propyl]-3,9-diazabicyclo[3.3.1]nonane can be quite intriguing due to its unique structural features. Here are key points regarding its solubility:

  • Polarity: The presence of the piperidyl group contributes to the overall polarity of the compound, potentially enhancing its solubility in polar solvents such as water.
  • Hydrophobic Characteristics: The benzyl group adds hydrophobic characteristics, which may lead to reduced solubility in nonpolar solvents.
  • Solvent Interactions: The solubility might vary depending on the solvent used. For instance, ethanol and DMSO could provide better solvation due to their ability to interact with both polar and nonpolar regions of the molecule.
  • Temperature Influence: Increased temperature typically enhances solubility, which is crucial when considering this compound's behaviour in practical applications.
  • Concentration Effects: At higher concentrations, solubility may plateau as saturation occurs, prompting a review of its applications in formulation.

In conclusion, while the detailed solubility profile of this compound may require specific experimental data, recognizing the balance between its polar and nonpolar features offers valuable insights into its behaviour in various solvents. Understanding these aspects can guide researchers in its practical applications and formulations.

Interesting facts

Interesting Facts about 3-benzyl-9-[2-(1-piperidyl)propyl]-3,9-diazabicyclo[3.3.1]nonane

The compound 3-benzyl-9-[2-(1-piperidyl)propyl]-3,9-diazabicyclo[3.3.1]nonane showcases intriguing characteristics that make it an important subject of study in medicinal chemistry. This compound belongs to the class of bicyclic structures, which are remarkable due to their unique three-dimensional conformation and potential biological activity.

Key Features

  • Structural Complexity: The bicyclic framework of this compound includes two nitrogen atoms that significantly influence its chemical properties and interaction with biological systems.
  • Biological Potential: Compounds of this type often exhibit pharmacological activities, making them candidates for drug development, particularly in treating neurological disorders.
  • Piperidine Moiety: The presence of the piperidine ring enhances its pharmacological versatility, contributing to its ability to traverse cell membranes and influence receptor activity.

Moreover, it is essential to acknowledge that:

  1. Ligand Interactions: The benzyl group can facilitate interactions with various receptors, enhancing the compound's capability to engage in biological activities.
  2. Research Focus: This compound has attracted the attention of researchers investigating novel therapeutic agents, leading to potential advancements in drug discovery.
  3. Synthetic Interest: The synthetic pathways leading to such bicyclic structures often involve interesting methodologies, including multi-step reactions that challenge the creativity and problem-solving skills of chemists.

In summary, 3-benzyl-9-[2-(1-piperidyl)propyl]-3,9-diazabicyclo[3.3.1]nonane exemplifies the fascinating intersection of structural chemistry and pharmacology, revealing a world of potential applications. As stated by leading researchers, "the road to innovation is often paved with complex molecules." The exploration of such compounds not only furthers scientific knowledge but may also lead to groundbreaking discoveries in medicine.