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Almotriptan malate

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Identification
Molecular formula
C17H25N3O2•C4H6O5
CAS number
154323-57-6
IUPAC name
3-benzyl-9-[2-(1-piperidyl)propyl]-3,9-diazabicyclo[3.3.1]nonane;hydrate;trihydrochloride
State
State
The compound is in solid state at room temperature, typically stored in airtight containers to preserve its integrity.
Melting point (Celsius)
170.00
Melting point (Kelvin)
443.15
Boiling point (Celsius)
322.00
Boiling point (Kelvin)
595.15
General information
Molecular weight
335.86g/mol
Molar mass
335.8630g/mol
Density
1.2900g/cm3
Appearence

Almotriptan malate appears as a white or almost white powder. The compound is typically crystalline in nature and must be handled with care to maintain its appearance and purity.

Comment on solubility

Solubility of 3-benzyl-9-[2-(1-piperidyl)propyl]-3,9-diazabicyclo[3.3.1]nonane;hydrate;trihydrochloride

The solubility of 3-benzyl-9-[2-(1-piperidyl)propyl]-3,9-diazabicyclo[3.3.1]nonane;hydrate;trihydrochloride can be quite intriguing due to the specific characteristics of this compound. Several factors influence its solubility:

  • Hydration state: As a hydrate, the presence of water can enhance solubility in polar solvents.
  • Salt form: Being a trihydrochloride salt often results in increased solubility in water compared to its free base due to ionic interactions.
  • Polarity: The overall polarity of the molecule, attributed to functional groups, will dictate its solubility in various solvents.

It is essential to note that ionic compounds typically demonstrate high solubility in water, while organic compounds may exhibit variable solubility depending on structural features. Thus, for this compound, the solubility may be markedly higher in aqueous solutions compared to non-polar solvents.

In summary, the solubility of this trihydrochloride salt is expected to be relatively high in polar solvents, particularly in water, due to its ionic nature. The interactions caused by hydration and the unique structure of the bicyclic compound play a significant role in its overall solubility profile.

Interesting facts

Interesting Facts about 3-benzyl-9-[2-(1-piperidyl)propyl]-3,9-diazabicyclo[3.3.1]nonane;hydrate;trihydrochloride

This compound, known as a bicyclic amine derivative, has garnered interest due to its unique structure and potential applications in the field of medicinal chemistry. Here are some intriguing aspects:

  • Structural Complexity: The bicyclic structure of this compound comprises two interconnected rings, which is characteristic of many biologically active molecules. This unique conformation can influence the compound's interaction with biological targets.
  • Pharmacological Potential: Compounds like this one that feature piperidine rings are often explored for their influence on neurotransmitter systems, potentially resulting in effects on mood or cognition.
  • Hydration and Salt Forms: This compound is presented as a trihydrochloride salt, which is noteworthy because the choice of salt forms can significantly affect the compound’s solubility and stability, crucial factors for pharmaceutical development.
  • Research Applications: Scientists engage with such compounds not only for their potential therapeutic uses but also as tools for studying receptor interactions, making them valuable in both drug discovery and neuroscience research.
  • Future Directions: Ongoing research into bicyclic amines like this one continues to unveil new insights into their mechanisms of action, leading to the potential development of novel therapies for various medical conditions.

In conclusion, the compound 3-benzyl-9-[2-(1-piperidyl)propyl]-3,9-diazabicyclo[3.3.1]nonane;hydrate;trihydrochloride represents a compelling area of study for chemists and pharmacologists alike, as they explore its diverse applications and implications in the world of science.

Synonyms
23462-20-6
3,9-Diazabicyclo(3.3.1)nonane, 3-benzyl-9-(2-piperidinopropyl)-, trihydrochloride, hydrate
3-Benzyl-9-(2-piperidinopropyl)-3,9-diazabicyclo(3.3.1)nonane trihydrochloride hydrate
RefChem:272785
DTXSID00946136
3-Benzyl-9-[2-(piperidin-1-yl)propyl]-3,9-diazabicyclo[3.3.1]nonane--hydrogen chloride--water (1/3/1)