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Tropisetron Hydrochloride

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Identification
Molecular formula
C24H34Cl3N3O3
CAS number
89565-68-4
IUPAC name
3-benzyl-9-[3-(1-piperidyl)propyl]-3,9-diazabicyclo[3.3.1]nonane;trihydrate;trihydrochloride
State
State

At room temperature, tropisetron hydrochloride is typically found in a solid state.

Melting point (Celsius)
248.00
Melting point (Kelvin)
521.15
Boiling point (Celsius)
110.00
Boiling point (Kelvin)
383.15
General information
Molecular weight
428.37g/mol
Molar mass
428.3700g/mol
Density
1.2000g/cm3
Appearence

Tropisetron hydrochloride appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 3-benzyl-9-[3-(1-piperidyl)propyl]-3,9-diazabicyclo[3.3.1]nonane;trihydrate;trihydrochloride

The solubility of the compound 3-benzyl-9-[3-(1-piperidyl)propyl]-3,9-diazabicyclo[3.3.1]nonane;trihydrate;trihydrochloride is significantly influenced by its molecular structure and the presence of both water and hydrochloride ions. Understanding its solubility can provide insights into its application and behavior in different environments.

Factors affecting solubility:

  • Hydrate Form: The presence of water molecules in the trihydrate form ensures that the compound has enhanced interaction with polar solvents, particularly water.
  • Hydrochloride Salt: Being a hydrochloride salt, it tends to be more soluble in aqueous solutions, owing to the ionic nature of the chloride ions.
  • Polarity: The compound's polarity plays a crucial role in its solubility; polar compounds generally exhibit higher solubility in polar solvents.

In general, this compound is expected to exhibit good solubility in water due to the following reasons:

  1. The presence of piperidyl and benzyl groups, which help in the solvation process.
  2. The trihydrochloride form, making it more favorable for dissolution.

In conclusion, compounds like 3-benzyl-9-[3-(1-piperidyl)propyl]-3,9-diazabicyclo[3.3.1]nonane;trihydrate;trihydrochloride demonstrate intriguing solubility properties, which are pivotal in pharmaceutical formulation and drug delivery. Such solubility characteristics can dictate dosage forms, bioavailability, and ultimately the efficacy of therapeutic agents.

Interesting facts

Exploring 3-benzyl-9-[3-(1-piperidyl)propyl]-3,9-diazabicyclo[3.3.1]nonane; trihydrate; trihydrochloride

The compound 3-benzyl-9-[3-(1-piperidyl)propyl]-3,9-diazabicyclo[3.3.1]nonane; trihydrate; trihydrochloride is a fascinating entity in the realm of chemistry, exhibiting unique structural and functional attributes. Here are some intriguing insights:

  • Complex Structure: This compound belongs to a novel class of bicyclic amines, characterized by its intricate bicyclo structure that includes two nitrogen atoms in a cycle, which can significantly impact its chemical behavior and interactions.
  • Applications in Medicine: Compounds with piperidine components often exhibit promising pharmacological activities. This particular compound could hold potential in drug development, particularly in the fields of psychiatric and neurological therapies.
  • Hydration Importance: The designation as a trihydrate indicates that it is associated with three water molecules. This hydration can influence the compound's stability and solubility, making it crucial for further applications in biological systems.
  • Chloride Salts: Being a trihydrochloride form is vital as chloride salts often improve the bioavailability of compounds, aiding in their absorption and efficacy when used therapeutically.
  • Research Potential: The unique structure opens avenues for research into its reactivity and interaction with biological systems. Its ability to modulate biological pathways can be an interesting topic for further exploration.

As we delve deeper into the chemistry of such compounds, understanding their structure-property relationships can lead to innovative applications in medicine and materials science. The combination of bicyclic structure and piperidine functionality renders it a subject of ongoing research, and its molecular design holds promise for potential therapeutic interventions. In the words of a renowned chemist, "Chemistry is the art of discovering solutions to complex challenges," and this compound certainly embodies that spirit.

Synonyms
23462-17-1
3,9-Diazabicyclo(3.3.1)nonane, 3-benzyl-9-(3-piperidinopropyl)-, hydrochloride, hydrate (1:3:3)
3-Benzyl-9-(3-piperidinopropyl)-3,9-diazabicyclo(3.3.1)nonane hydrochloride hydrate
RefChem:272789
DTXSID20946133
3-Benzyl-9-[3-(piperidin-1-yl)propyl]-3,9-diazabicyclo[3.3.1]nonane--hydrogen chloride--water (1/3/3)