Skip to main content

3-benzyl-N,N-dimethylindol-5-amine

ADVERTISEMENT
Identification
Molecular formula
C17H18N2
CAS number
84245-28-1
IUPAC name
3-benzyl-N,N-dimethyl-1H-indol-5-amine
State
State
At room temperature, it is in a solid state, often in crystalline form, and is typically white to off-white in color.
Melting point (Celsius)
87.00
Melting point (Kelvin)
360.15
Boiling point (Celsius)
380.00
Boiling point (Kelvin)
653.15
General information
Molecular weight
262.35g/mol
Molar mass
262.3540g/mol
Density
1.1500g/cm3
Appearence

The compound is typically a solid at room temperature. It can appear as a crystalline powder, usually white to off-white in color.

Comment on solubility

Solubility of 3-benzyl-N,N-dimethyl-1H-indol-5-amine

The solubility of 3-benzyl-N,N-dimethyl-1H-indol-5-amine is an intriguing topic, as it often behaves quite differently in various solvents. Understanding its solubility characteristics can help in applications such as drug formulation and synthesis. Key aspects of its solubility include:

  • Polar vs. Non-Polar Solvents: This compound is expected to have limited solubility in polar solvents, given its hydrophobic benzyl and indole moieties. Conversely, it may exhibit better solubility in non-polar organic solvents.
  • Temperature Dependency: As with many organic compounds, 3-benzyl-N,N-dimethyl-1H-indol-5-amine may display increased solubility at elevated temperatures.
  • pH Effects: The protonation state can influence solubility, implying that its solubility might vary significantly with changes in pH, particularly in biological systems.

In conclusion, while the solubility of 3-benzyl-N,N-dimethyl-1H-indol-5-amine in specific solvents can be predicted based on its structural features, empirical testing would provide the most accurate insights. Always remember that “**solubility is an important factor** in determining bioavailability and the efficacy of pharmaceuticals.”

Interesting facts

Interesting Facts about 3-benzyl-N,N-dimethyl-1H-indol-5-amine

3-benzyl-N,N-dimethyl-1H-indol-5-amine is a fascinating compound that belongs to the class of indoles, which are well-known for their diverse biological activities. Here are some intriguing aspects of this compound:

  • Biological Significance: Indole derivatives, including this compound, have been studied for their potential medicinal properties. They often exhibit anticancer, antifungal, and antimicrobial activities.
  • Psychoactive Potential: Compounds with indole structures are known to have effects on the central nervous system, making them of interest in neuropharmacology and psychology.
  • Structure-Activity Relationship (SAR): Studying the SAR of indole compounds helps in understanding how different substitutions impact their effectiveness and toxicity, making this compound a valuable subject for researchers.
  • Versatile Synthesis: The synthetic routes to create 3-benzyl-N,N-dimethyl-1H-indol-5-amine can involve various methodologies, adding to the intrigue of how chemists can manipulate its properties.
  • Potential Applications: Aside from pharmaceuticals, this compound could have applications in designing new materials, dyes, or even as precursors in organic synthesis.

To quote a prominent chemist, "The beauty of chemistry lies in its ability to reveal the unseen connections between the simplest building blocks of matter." The study of such compounds opens up new avenues for exploration and innovation in multiple scientific fields.

In summary, 3-benzyl-N,N-dimethyl-1H-indol-5-amine stands out not only for its structure but for the vast potential it holds in the realms of medicine and materials science. Its exploration encourages a deeper understanding of both chemical properties and biological interactions.

Synonyms
5-Dimethylamino-3-benzylindole
INDOLE, 3-BENZYL-5-(DIMETHYLAMINO)-
BRN 0482518
6843-31-8
DTXSID10218553
5-22-11-00091 (Beilstein Handbook Reference)
DTXCID60141044
3-benzyl-N,N-dimethyl-1H-indol-5-amine