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General Structure of 3-benzyloxy Steroids

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Identification
Molecular formula
C26H32O3
CAS number
NA
IUPAC name
3-benzyloxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-16,17-diol
State
State

This compound is typically a solid at room temperature, often found as a powder or crystalline solid.

Melting point (Celsius)
142.00
Melting point (Kelvin)
415.15
Boiling point (Celsius)
477.90
Boiling point (Kelvin)
751.05
General information
Molecular weight
380.54g/mol
Molar mass
380.5400g/mol
Density
1.1400g/cm3
Appearence

3-benzyloxy steroids like 3-benzyloxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-16,17-diol are typically solid at room temperature. They often appear as white to off-white crystalline powders.

Comment on solubility

Solubility of 3-benzyloxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-16,17-diol (C26H32O3)

The solubility of 3-benzyloxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-16,17-diol reflects its complex molecular structure and chemical characteristics. Here are some key points regarding its solubility:

  • Polarity: This compound exhibits a moderate degree of polarity due to the presence of hydroxyl (–OH) groups, which can form hydrogen bonds with water.
  • Solvent Compatibility: It is likely to be soluble in organic solvents such as ethanol, dimethyl sulfoxide (DMSO), and acetone but may have limited solubility in water.
  • Temperature Effects: The solubility may increase with temperature, a typical behavior for compounds with hydrophobic regions, aiding dissolving in certain solvents.
  • Impurities: Presence of impurities or co-solvents can significantly affect solubility, potentially resulting in variations from typical solubility behaviors.

In summary, while 3-benzyloxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-16,17-diol may exhibit moderate solubility in particular solvents, its overall behavior is complex and influenced by several factors such as temperature, polarity, and the presence of other substances. Understanding these aspects is crucial for applications involving this compound.

Interesting facts

Interesting Facts about 3-Benzyloxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-16,17-diol

This fascinating compound is noteworthy for several reasons, making it a compelling subject for study in organic chemistry and medicinal research.

Structural Complexity

The structure of this compound consists of multiple fused rings, specifically a decahydrocyclopenta[a]phenanthrene framework, which contributes to its interesting chemical behavior. The complexity of its molecular architecture opens up a variety of interactions with biological targets.

Biological Significance

Many compounds like this one, characterized by their unique fusion of rings and hydroxyl functionalities, are studied for their potential biological activities. Some key points include:

  • Potential Medicinal Properties: Compounds with multiple hydroxyl groups often exhibit interesting pharmacological properties, possibly influencing cell signaling pathways and exhibiting antioxidant capabilities.
  • Natural Products: The structure resembles those of various natural products, which can be derived from plant sources, suggesting the potential for discovery in traditional medicine.

Synthetic Pathways

Synthesizing this compound can provide insights into synthetic organic chemistry, with challenges associated with maintaining stereochemistry and ensuring regioselectivity during the synthesis process. Techniques such as:

  • Multi-step synthesis from simpler precursors
  • Use of protecting groups to manage functional groups during reactions
  • Application of modern coupling techniques

are vital in the successful creation of such intricate molecules.

Research Implications

As research continues into the potential uses of this and similar compounds, it raises intriguing questions about:

  • The relationship between molecular structure and biological activity
  • How modifications to the structure can enhance efficacy or selectivity for specific biological targets

In summary, the study of 3-benzyloxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-16,17-diol presents an exciting intersection of synthetic chemistry, structure-activity relationships, and potential therapeutic applications.

Synonyms
(16alpha,17alpha)-3-(PhenylMethoxy)-estra-1,3,5(10)-triene-16,17-diol
CHEMBL1337771
NCGC00095320-01
NS00005801