Skip to main content

Melphalan

ADVERTISEMENT
Identification
Molecular formula
C13H18Cl2N2O2
CAS number
148-82-3
IUPAC name
3-[bis(2-chloroethyl)amino]-4-methoxy-benzoic acid
State
State

At room temperature, Melphalan exists in a solid state, typically as a powder. Its physical state can be influenced by environmental conditions such as temperature and humidity.

Melting point (Celsius)
182.00
Melting point (Kelvin)
455.15
Boiling point (Celsius)
330.47
Boiling point (Kelvin)
603.62
General information
Molecular weight
305.19g/mol
Molar mass
305.1910g/mol
Density
1.2000g/cm3
Appearence

Melphalan, also known as L-PAM or L-sarcolysin, typically appears as a white to off-white crystalline powder. The appearance can vary slightly based on the specific form and purity of the compound.

Comment on solubility

Solubility of 3-[bis(2-chloroethyl)amino]-4-methoxy-benzoic acid

The solubility of 3-[bis(2-chloroethyl)amino]-4-methoxy-benzoic acid is influenced by several factors, which can be understood by examining its chemical structure and the interactions it may engage in:

  • Solvent Polarity: This compound may exhibit better solubility in polar solvents due to its carboxylic acid group, which can participate in hydrogen bonding.
  • Hydrogen Bonding: The presence of the carboxylic acid functional group allows for interactions with water molecules, potentially enhancing its solubility.
  • Alkyl Chain Influence: The bis(2-chloroethyl) group can introduce hydrophobic character, which might limit solubility in strictly polar solvents while enhancing solubility in organic solvents.
  • Temperature Effects: Increased temperatures often lead to higher solubility levels for many compounds; thus, heating the solvent may prove beneficial.

In summary, while the solubility of 3-[bis(2-chloroethyl)amino]-4-methoxy-benzoic acid may vary depending on environmental conditions, it's reasonable to infer that its unique structure will allow for some degree of solubility in both polar and non-polar solvents. Understanding these nuances is key for effective application in various chemical processes.

Interesting facts

Interesting Facts about 3-[bis(2-chloroethyl)amino]-4-methoxy-benzoic acid

3-[bis(2-chloroethyl)amino]-4-methoxy-benzoic acid, commonly known in some circles as a derivative with potential therapeutic uses, has a fascinating structure that incorporates both an aromatic system and an amino group. Here are several noteworthy aspects of this compound:

  • Chemical Fragments: This compound features a benzoic acid backbone, which enhances its acidity and the potential for engaging in hydrogen bonding.
  • Biological Relevance: The chlorinated ethyl groups in its structure suggest possible activity against cancer, specifically in the realm of chemotherapy agents. Such modifications have been known to improve the compound's efficacy in targeting cancer cells.
  • Mechanism of Action: Compounds like this are often designed to interfere with cellular mechanisms such as DNA replication or repair, making them potentially valuable in treatment protocols where traditional methods fall short.

As scientists delve deeper into the pharmacological properties of compounds like 3-[bis(2-chloroethyl)amino]-4-methoxy-benzoic acid, the hope is to innovate more effective drugs that tackle resistant forms of cancer. The integration of various chemical functionalities in a single molecule is not only a testament to chemical ingenuity but also illuminates pathways for therapeutic advancements in oncology.

In conclusion, while the journey of developing and studying such compounds is complex, the potential benefits to human health are profound and represent a crucial area of ongoing research. As always in the world of chemistry, the synthesis and application of novel compounds will continue to reveal their secrets, driving the field forward.

Synonyms
24812-96-2
3-[bis(2-chloroethyl)amino]-4-methoxybenzoic acid
p-ANISIC ACID, 3-(BIS(2-CHLOROETHYL)AMINO)-
NSC-146172
TLK455V39J
p-Anisic acid, 3-[bis(2-chloroethyl)amino]-
DTXSID80179506
Benzoic acid, 3-(bis(2-chloroethyl)amino)-4-methoxy-
Benzoic acid, 3-[bis(2-chloroethyl)amino]-4-methoxy-
3-(Bis(2-chloroethyl)amino)-4-methoxybenzoic acid
RefChem:1094157
DTXCID70101997
IOB 177
NSC 146172
BRN 2755201
3-(Bis(2-chloroethyl)amino)-p-anisic acid
SCHEMBL4134021
PKFSXBZXFYABSS-UHFFFAOYSA-N
NSC146172
3-bis(2'-chloroethyl)amino-4-methoxybenzoic acid