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3-bromopropane-1,2-diol

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Identification
Molecular formula
C3H7BrO2
CAS number
10473-98-0
IUPAC name
3-bromopropane-1,2-diol
State
State

At room temperature, 3-bromopropane-1,2-diol can exist either as a viscous liquid or as a crystalline solid depending on purity and specific conditions such as moisture content and temperature.

Melting point (Celsius)
38.00
Melting point (Kelvin)
311.15
Boiling point (Celsius)
130.00
Boiling point (Kelvin)
403.15
General information
Molecular weight
155.99g/mol
Molar mass
155.9890g/mol
Density
2.0080g/cm3
Appearence

3-Bromopropane-1,2-diol is typically found in a colorless to pale yellow viscous liquid form. It may appear as a colorless crystalline solid when purified. This compound is hygroscopic and may become a bit sticky when exposed to moist air due to its hygroscopic nature.

Comment on solubility

Solubility of 3-bromopropane-1,2-diol

3-bromopropane-1,2-diol, characterized by its structure and functional groups, displays interesting solubility properties. Generally, the solubility of a compound can be influenced by factors such as:

  • Polarity: The presence of hydroxyl (-OH) groups contributes to the polarity, enhancing its ability to dissolve in polar solvents.
  • Hydrogen Bonding: The -OH groups allow for hydrogen bonding with water molecules, significantly increasing solubility in water.
  • Chain Length: The three-carbon chain length of 3-bromopropane-1,2-diol does not hinder solubility but may limit it in non-polar solvents.

In practical terms, 3-bromopropane-1,2-diol is highly soluble in water due to the strong interactions between its hydroxyl groups and water. This characteristic makes it useful in various chemical applications. However, its solubility is limited in non-polar solvents like hexane, where the compound may not dissolve effectively.

As a well-balanced molecule, it stands as an excellent example of how molecular structure influences solubility, reflecting the iconic phrase: "Like dissolves like."

Interesting facts

Interesting Facts about 3-Bromopropane-1,2-diol

3-Bromopropane-1,2-diol is an intriguing compound with multiple applications and properties that make it noteworthy in the field of chemistry. Here are some fascinating aspects to consider:

  • Structural Significance: The compound features a bromine atom attached to a carbon chain that also has two hydroxyl (-OH) groups. This unique 3D arrangement can lead to interesting reactivity and interactions with other molecules.
  • Role in Organic Synthesis: 3-Bromopropane-1,2-diol is often utilized as an intermediate in organic synthesis. It plays a key role in the production of various pharmaceuticals and agrochemicals, making it important for researchers in medicinal and agricultural chemistry.
  • Chiral Centers: This compound may exhibit chirality due to the presence of carbon atoms bonded to different groups, allowing chemists to explore enantiomers that may have distinct biological activites.
  • Hygroscopic Properties: The hydroxyl groups contribute to the hygroscopic nature of the compound, indicating its ability to absorb moisture from the environment. This property can impact its stability and handling requirements in laboratory settings.
  • Potential Use in Biomaterials: Due to its reactive groups, 3-bromopropane-1,2-diol can be employed in the development of biomaterials, particularly in creating hydrogels or scaffolds for tissue engineering applications.

In conclusion, the exploration of 3-bromopropane-1,2-diol reveals its multifaceted nature, spanning from its structural characteristics to its practical applications in various scientific domains. It exemplifies how a simple compound can possess remarkable capabilities for innovation in chemistry.

Synonyms
3-Bromo-1,2-propanediol
3-Bromopropane-1,2-diol
alpha-Bromohydrin
Glycerol bromohydrin
Bromodeoxyglycerol
1-Bromo-2,3-propanediol
(RS)-3-bromo-1,2-propanediol
EINECS 225-186-2
AS532NK8NE
.alpha.-Bromohydrin
BRN 1719124
CHEBI:18719
DTXSID20963729
2-01-00-00540 (Beilstein Handbook Reference)
(A+-)-Glycerol 1-bromohydrin
DTXCID601021067
sibfqouhocrxdl-uhfffaoysa-n
4704-77-2
Monobromoglycerol
1,2-Propanediol, 3-bromo-
3-Bromodeoxyglycerol
MFCD00004711
bromopropane-2,3-diol
bromomethyl ethylene glycol
UNII-AS532NK8NE
3-bromo-propan-1,2-diol
3-bromo-propane-1,2-diol
SCHEMBL370747
(+/-)-Glycerol 1-bromohydrin
CHEMBL3276497
2,3-dihydroxyl-n-propyl bromide
3-Bromo-1,2-propanediol, 97%
MFA49063
MSK15326
WZB82048
1-BROMO-2,3-DIHYDROXYPROPANE
AKOS015916343
SB46822
SB47699
BP-21425
BS-28661
NS00044992
D84178
EN300-214063
3-Bromo-1,2-propanediol, technical, >=96% (GC)
Q27109088