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3-Bromopropanoic acid

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Identification
Molecular formula
C3H5BrO2
CAS number
590-92-1
IUPAC name
3-bromopropanoic acid
State
State

At room temperature, 3-bromopropanoic acid is typically in a solid crystalline state, but can appear as a liquid depending on the environmental conditions.

Melting point (Celsius)
63.00
Melting point (Kelvin)
336.15
Boiling point (Celsius)
208.00
Boiling point (Kelvin)
481.15
General information
Molecular weight
152.97g/mol
Molar mass
152.9610g/mol
Density
1.7570g/cm3
Appearence

3-Bromopropanoic acid is a colorless to light yellow liquid with an acrid odor. It can also crystallize as white or slightly yellowish prismatic crystals under certain conditions.

Comment on solubility

Solubility of 3-bromopropanoic acid

3-bromopropanoic acid, with the chemical formula C3H5BrO2, exhibits interesting solubility characteristics that are worth noting:

  • Polar Nature: The presence of the carboxylic acid group (-COOH) contributes to its polarity, enhancing its ability to dissolve in polar solvents.
  • Water Solubility: 3-bromopropanoic acid is generally soluble in water due to hydrogen bonding interactions between the acid group and the solvent molecules.
  • Solubility in Organic Solvents: It is also soluble in various organic solvents like ethanol and acetone, owing to its hydrophobic hydrocarbon chain.

This compound's **solubility** is influenced by a variety of factors, including:

  1. Temperature: As temperature increases, solubility often improves.
  2. pH Levels: The ionization state of the molecule can affect solubility; at higher pH levels, the carboxylic acid may become deprotonated, increasing solubility.
  3. Presence of Salts: The addition of salts can sometimes enhance solubility through a phenomenon known as "salting in."

The interaction of 3-bromopropanoic acid with solvent molecules makes it a compound with versatile solubility dynamics, broadening its applicability in both laboratory and industrial settings.

Interesting facts

Interesting Facts About 3-bromopropanoic Acid

3-bromopropanoic acid is a fascinating compound with numerous applications and intriguing characteristics. As a member of the carboxylic acid family, it is recognized for its unique functional group and reactivity.

Key Characteristics

  • Structural Significance: The presence of the bromine atom in the molecule makes it a brominated carboxylic acid, which can significantly impact its reactivity and properties compared to non-brominated counterparts.
  • Biological Activity: This compound exhibits interesting biological properties, and its derivatives are studied for potential use in pharmaceuticals. The addition of a bromine atom can enhance the antibacterial properties of compounds, making them valuable in medicinal chemistry.
  • Role in Synthesis: 3-bromopropanoic acid serves as a useful intermediate in organic synthesis. It can participate in various reactions, including esterification and nucleophilic substitution, allowing the introduction of a variety of functional groups.

Applications

  • Pharmaceutical Development: Research has shown that brominated derivatives can exhibit important pharmacological properties.
  • Agricultural Chemistry: Its structural features may also lend itself to applications in agrochemicals, enhancing crop protection strategies.

As noted in the field, "the introduction of halogens (like bromine) can remarkably change the biological interactions of compounds"—a mantra that reinforces the importance of studying compounds like 3-bromopropanoic acid. By understanding the subtleties of its reactivity and the implications of its structure, chemists can harness its potential in innovative ways.

The ongoing exploration of 3-bromopropanoic acid is a testament to the myriad possibilities that exist within the universe of chemical compounds, showcasing how a simple modification can lead to significant advancements in both research and application.

Synonyms
3-Bromopropionic acid
3-BROMOPROPANOIC ACID
Propanoic acid, 3-bromo-
beta-Bromopropanoic acid
HSDB 5496
UNII-WFZ7CSR69R
NSC 2638
EINECS 209-694-1
BRN 1071333
AI3-18966
NSC-2638
DTXSID9060443
.BETA.-BROMOPROPANOIC ACID
PROPIONIC ACID, .BETA.-BROMO-
3bromopropanoic acid
3bromopropionic acid
2Carboxyethyl bromide
betaBromopropanoic acid
betaBromopropionic acid
Propanoic acid, 3bromo
Propionic acid, 3bromo
DTXCID1042520
PROPIONIC ACID, BETA-BROMO-
4-02-00-00764 (beilstein handbook reference)
dhxnzycxmfbmhe-uhfffaoysa-n
inchi=1/c3h5bro2/c4-2-1-3(5)6/h1-2h2,(h,5,6
un3261
590-92-1
beta-Bromopropionic acid
Propionic acid, 3-bromo-
2-Carboxyethyl bromide
3-Bromo-propionic acid
.beta.-Bromopropionic acid
WFZ7CSR69R
2-Carboxyethyl Bromide; 3-Bromopropanoic Acid; NSC 2638; ss-Bromopropanoic Acid; ss-Bromopropionic Acid
MFCD00002763
3- bromopropionic acid
3-bromo propionic acid
WLN: QV2E
Br(CH2)2CO2H
SCHEMBL28472
3-Bromopropionic acid, 97%
CHEMBL4569339
NSC2638
STR00360
STL282736
AKOS005111073
SB40497
.BETA.-BROMOPROPIONIC ACID [MI]
BP-31254
DB-003922
DB-257298
B0645
NS00034080
EN300-20490
P17146
Q22133309
F2191-0199