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Iopromide

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Identification
Molecular formula
C18H24I3N3O8
CAS number
73334-07-3
IUPAC name
3-[(butanoylamino)methyl]-5-[[8-[3-[(butanoylamino)methyl]-5-carboxy-2,4,6-triiodo-anilino]-8-oxo-octanoyl]amino]-2,4,6-triiodo-benzoic acid
State
State

At room temperature, Iopromide is primarily encountered as a liquid due to its formulation in solutions, though it is a solid when not in solution form.

Melting point (Celsius)
168.00
Melting point (Kelvin)
441.15
Boiling point (Celsius)
203.00
Boiling point (Kelvin)
476.15
General information
Molecular weight
791.12g/mol
Molar mass
791.1200g/mol
Density
1.4450g/cm3
Appearence

Iopromide is a white to off-white crystalline powder. It is often provided in solution for use as a non-ionic, water-soluble radiographic contrast agent. The solutions are clear, colorless to pale yellow.

Comment on solubility

Solubility of 3-[(butanoylamino)methyl]-5-[[8-[3-[(butanoylamino)methyl]-5-carboxy-2,4,6-triiodo-anilino]-8-oxo-octanoyl]amino]-2,4,6-triiodo-benzoic acid

The solubility of complex chemical compounds like 3-[(butanoylamino)methyl]-5-[[8-[3-[(butanoylamino)methyl]-5-carboxy-2,4,6-triiodo-anilino]-8-oxo-octanoyl]amino]-2,4,6-triiodo-benzoic acid can often be influenced by various factors, including polarity and functional groups present in the structure. This specific compound, being quite large and complex, is expected to have limited solubility in non-polar solvents.

Key factors affecting solubility:

  • Polarity: Compounds with notable polar functional groups may exhibit greater solubility in polar solvents (e.g., water), while those with predominantly hydrophobic regions typically dissolve better in organic solvents.
  • Hydrogen bonding: The presence of amino and carboxylic acid groups may enhance solubility due to the ability to form hydrogen bonds with solvent molecules.
  • Molecular size: Larger molecules may encounter steric hindrance, reducing their solubility compared to smaller, simpler compounds.

In the case of this compound, researchers might find that:

  • It shows reasonable solubility in dimethyl sulfoxide (DMSO) and dimethylformamide (DMF) due to their polar nature.
  • It is poorly soluble in aqueous environments, making concentration adjustments critical in biological applications.

For any practical applications, conducting solubility tests across a variety of solvents is crucial to establish effective usage parameters.

Interesting facts

Interesting Facts about 3-[(butanoylamino)methyl]-5-[[8-[3-[(butanoylamino)methyl]-5-carboxy-2,4,6-triiodo-anilino]-8-oxo-octanoyl]amino]-2,4,6-triiodo-benzoic acid

This complex compound, belonging to a class of chemical entities with significant biological implications, showcases a unique structure that supports crucial functions in medicinal chemistry. Here are some noteworthy aspects:

  • Structural Intricacy: The compound features a multi-functional framework with both amine and carboxyl groups, rendering it highly reactive and versatile in various chemical environments.
  • Iodine Substitution: The presence of multiple iodine atoms not only increases the compound's molecular complexity but also enhances its affinity for certain biological targets, making it a topic of interest for researchers studying imaging agents.
  • Biological Activity: Its structural components suggest potential applications in pharmaceutical formulations, particularly in targeting specific pathways associated with metabolic disorders or cancer.
  • Chemical Versatility: The butanoylamino groups positioned in the compound may influence its solubility and binding properties, making it suitable for further modifications and optimization in drug design.
  • Potent Interactions: This compound may exhibit interesting interactions with cellular receptors or enzymes, contributing to its potential utility in therapeutics.

Overall, the detailed composition and structural elements present in this compound provide a rich foundation for further study. As one studies its properties and behaviors, they might ponder: "What biological pathways could this compound influence?"

Researchers continue to delve into the myriad implications of such compounds, exploring how innovations in medicinal chemistry can lead to groundbreaking advancements in healthcare and treatment methodologies.

Synonyms
25903-30-4
BENZOIC ACID, 3,3'-(SUBEROYLDIIMINO)BIS(5-(BUTYRAMIDOMETHYL)-2,4,6-TRIIODO-
3,3'-Suberoyldiiminobis(5-(butyramidomethyl)-2,4,6-triiodobenzoic acid)
DTXSID20180570
RefChem:326966
DTXCID60103061