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Iodixanol

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Identification
Molecular formula
C35H44I6N6O15
CAS number
92339-11-2
IUPAC name
3-[(butanoylamino)methyl]-5-[[9-[3-[(butanoylamino)methyl]-5-carboxy-2,4,6-triiodo-anilino]-9-oxo-nonanoyl]amino]-2,4,6-triiodo-benzoic acid
State
State

At room temperature, iodixanol is in a solid state, specifically as a crystalline powder. It is used in solutions as a contrast medium for imaging studies.

Melting point (Celsius)
184.00
Melting point (Kelvin)
457.15
Boiling point (Celsius)
392.00
Boiling point (Kelvin)
665.15
General information
Molecular weight
1550.20g/mol
Molar mass
1 550.1980g/mol
Density
3.2300g/cm3
Appearence
Iodixanol typically appears as a white or off-white crystalline powder. Its high iodine content contributes to its density and opaqueness under X-ray imaging, which is why it is commonly used as a contrast agent in radiology.
Comment on solubility

Solubility of 3-[(butanoylamino)methyl]-5-[[9-[3-[(butanoylamino)methyl]-5-carboxy-2,4,6-triiodo-anilino]-9-oxo-nonanoyl]amino]-2,4,6-triiodo-benzoic acid

The solubility of this complex compound can be quite intriguing due to its unique structure. The presence of multiple functional groups influences its interaction with solvents. Here are some key points regarding its solubility:

  • Polarity: Compounds with amine and carboxylic acid groups tend to be polar, which can enhance solubility in polar solvents like water.
  • Hydrophobic Regions: The butanoyl groups in the structure may contribute to hydrophobic characteristics, potentially limiting solubility in aqueous solutions.
  • Solvent Dependence: Such compounds may show varying solubility based on the solvent system employed, possibly being more soluble in organic solvents as opposed to polar solvents.
  • pH Sensitivity: The solubility can also change with pH levels due to the ionizable groups, making it more soluble in acidic conditions compared to neutral or basic environments.

In conclusion, the solubility of this compound is influenced by its distinct chemical features, with its behavior being governed by the balance of hydrophilic and hydrophobic interactions. Understanding these interactions is crucial for predicting how the compound will behave in different environments.

Interesting facts

3-[(butanoylamino)methyl]-5-[[9-[3-[(butanoylamino)methyl]-5-carboxy-2,4,6-triiodo-anilino]-9-oxo-nonanoyl]amino]-2,4,6-triiodo-benzoic acid

This complex compound, often referred to as a derivative of iodinated benzamide, holds a significant place in research and medical applications, particularly in the fields of medicinal chemistry and molecular imaging. Its unique structure demonstrates a compelling combination of various functional groups, which allows for its intriguing behavior and potential applications.

Interesting Aspects of the Compound

  • Iodine-rich Structure: The presence of multiple iodine atoms within the compound enhances its radiological properties, making it valuable for imaging techniques such as single-photon emission computed tomography (SPECT) and positron emission tomography (PET).
  • Potential Therapeutic Applications: Due to its ability to selectively target specific biological pathways, it is being explored for use in cancer therapeutics, particularly in delivering localized treatments to tumors.
  • Functionalization: The various functional groups in the compound, including carboxylic acids and amides, allow for extensive modification, providing avenues for optimizing its biological activity and efficacy.
  • Research Tool: This compound serves as a model in studies investigating the interactions between pharmaceuticals and biological systems, elucidating mechanisms of drug action and resistance.
  • Promising Contrast Agent: Given its unique properties, it has potential as a contrast agent in diagnostic imaging, enhancing the visibility of tissues and organs in medical assessments.

Research surrounding this compound continues to unveil its complex behavior and capabilities, reflecting the ongoing fascination in the field of chemistry with how structural nuances can lead to innovative solutions in healthcare.

Synonyms
25903-31-5
BENZOIC ACID, 3,3'-(AZELAOYLDIIMINO)BIS(5-(BUTYRAMIDOMETHYL)-2,4,6-TRIIODO-
3,3'-(Azelaoyldiimino)bis(5-(butyramidomethyl)-2,4,6-triiodobenzoic acid)
DTXSID80180571
RefChem:326943
DTXCID20103062