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3-Butyl-3-phenylazetidin-2-one

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Identification
Molecular formula
C13H17NO
CAS number
25599-02-6
IUPAC name
3-butyl-3-phenyl-azetidin-2-one
State
State

At room temperature, 3-butyl-3-phenylazetidin-2-one is in a solid state, appearing as a white to off-white crystalline powder.

Melting point (Celsius)
76.50
Melting point (Kelvin)
349.70
Boiling point (Celsius)
292.30
Boiling point (Kelvin)
565.50
General information
Molecular weight
203.28g/mol
Molar mass
203.2810g/mol
Density
1.0944g/cm3
Appearence

3-Butyl-3-phenylazetidin-2-one is typically a crystalline solid at room temperature. It appears as a white to off-white powder with no significant odor.

Comment on solubility

Solubility of 3-butyl-3-phenyl-azetidin-2-one

The solubility of 3-butyl-3-phenyl-azetidin-2-one can be quite intriguing due to its structural properties. This compound, characterized by its butyl and phenyl groups attached to a cyclic azetidinone framework, presents unique interactions with solvents.

Key Aspects of Solubility:

  • Polarity: The presence of the butyl group contributes to a relatively non-polar character, while the phenyl ring can enhance solubility in organic solvents.
  • Solvent Compatibility: Generally, 3-butyl-3-phenyl-azetidin-2-one is more soluble in organic solvents such as:
    • Ethyl acetate
    • Toluene
    • Acetone
    • Chloroform
  • Water Solubility: This compound isn’t expected to be significantly soluble in water due to its hydrophobic characteristics, which can hinder its interaction with polar solvent molecules.

As a general insight, the solubility of azetidinones like 3-butyl-3-phenyl-azetidin-2-one can vary based on:

  • Temperature
  • Concentration
  • Presence of other solutes

This variability makes empirical testing valuable for establishing precise solubility parameters. As always, it is advisable to conduct solubility experiments under controlled conditions to achieve accurate results.

Interesting facts

Interesting Facts about 3-butyl-3-phenyl-azetidin-2-one

3-butyl-3-phenyl-azetidin-2-one is a fascinating compound that belongs to the class of azetidines, which are four-membered saturated heterocycles.

Unique Structural Features

This compound showcases several intriguing structural characteristics:

  • Azetidine Ring: The presence of the azetidine ring provides it with unique properties, making it a subject of interest in organic chemistry.
  • Substituents: The butyl and phenyl groups contribute to its chemical reactivity and potential applications in various fields.

Potential Applications

3-butyl-3-phenyl-azetidin-2-one also has notable applications:

  • Pharmaceuticals: Compounds containing the azetidine structure have been explored for their medicinal properties, including antifungal and anti-inflammatory activities.
  • Material Science: The structural integrity of azetidine derivatives may lend themselves to innovative materials with desirable mechanical properties.

Research and Synthesis

The synthesis of 3-butyl-3-phenyl-azetidin-2-one can be achieved through various organic reactions, which allows chemists to explore different synthetic pathways. This makes it an excellent compound for students and researchers looking to hone their organic synthesis skills:

  • Challenges in Synthesis: The construction of the azetidine ring often poses synthetic challenges, helping to cultivate problem-solving skills in chemists.
  • Insights into Reactivity: Studying this compound can provide insights into how substituents affect reactivity and stability within cyclic structures.

In summary, 3-butyl-3-phenyl-azetidin-2-one is more than just a simple molecule; its structure and potential applications open doors to a multitude of chemical explorations and innovations in both academic and industrial settings.

Synonyms
3-butyl-3-phenylazetidin-2-one
17719-30-1
3-Butyl-3-phenyl-2-azetidinone
L 1721
BRN 0174019
3-Butil-3-finil-2-azetidinone [Italian]
2-AZETIDINONE, 3-BUTYL-3-PHENYL-
3-Butil-3-finil-2-azetidinone
DTXSID50938905
3-Butyl-3-phenyl-3,4-dihydroazet-2-ol