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Baclofen

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Identification
Molecular formula
C10H12ClNO2
CAS number
1134-47-0
IUPAC name
3-(butylaminomethyl)-1,7,7-trimethyl-norbornan-2-one
State
State

At room temperature, Baclofen exists as a solid.

Melting point (Celsius)
206.00
Melting point (Kelvin)
479.20
Boiling point (Celsius)
362.10
Boiling point (Kelvin)
635.30
General information
Molecular weight
213.28g/mol
Molar mass
213.2820g/mol
Density
1.1450g/cm3
Appearence

Baclofen is typically available as a white to off-white crystalline powder.

Comment on solubility

Solubility Overview

The solubility of 3-(butylaminomethyl)-1,7,7-trimethyl-norbornan-2-one is influenced by various factors, including its molecular structure and the presence of functional groups. Understanding its solubility characteristics can provide insight into its behavior in different environments.

Key Factors Affecting Solubility

  • Polarity: The presence of the amine group (-NH2) contributes to the compound's polarity, which may enhance solubility in polar solvents such as water.
  • Hydrophobic Regions: The butyl chain and the norbornane structure contribute hydrophobic properties, potentially decreasing solubility in water but increasing it in organic solvents.
  • Temperature: As with many organic compounds, solubility can be temperature-dependent, with higher temperatures often improving solubility.
  • pH Levels: The solubility in aqueous environments can be significantly affected by the pH due to the potential protonation of amine groups.

Practical Implications

Researchers and chemists should consider the following when evaluating solubility:

  • Use in Formulations: If used in medicinal or industrial formulations, understanding its solubility will aid in optimizing concentrations.
  • Stability: Solubility influences stability; compounds that are poorly soluble may precipitate out of solution, impacting efficacy.

In conclusion, while the specific solubility of 3-(butylaminomethyl)-1,7,7-trimethyl-norbornan-2-one requires empirical data for precise characterization, its structural features suggest it exhibits unique solubility dynamics that can be both advantageous and limiting depending on the application. Adequate exploration into experimental solubility tests is essential for accurate assessments.

Interesting facts

Interesting Facts about 3-(butylaminomethyl)-1,7,7-trimethyl-norbornan-2-one

3-(butylaminomethyl)-1,7,7-trimethyl-norbornan-2-one is a fascinating compound with a unique structure and potential applications. Here are some intriguing aspects of this compound:

  • Unique Structure: The compound features a norbornane framework, which is known for its strain and the resulting unique chemical reactivity. Its bicyclic structure is noted for excellent rigidity that can influence the behavior of substituents.
  • Biological Relevance: Compounds like this one may act as intermediates in organic synthesis or could be studied for their biological activity. The incorporation of an amine functional group often enhances the biological properties relevant in pharmaceutical research.
  • Synthesis Challenges: The preparation of such complex molecules often demands advanced synthetic techniques, including multiple reaction steps and careful control of reaction conditions, which makes the study of this compound particularly engaging for synthetic chemists.
  • Potential Applications: The presence of both amine and ketone functional groups suggests possible applications in the development of agrochemicals or in the formulation of specialty chemicals.

As a chemist or student delving into organic chemistry, understanding compounds like 3-(butylaminomethyl)-1,7,7-trimethyl-norbornan-2-one opens doors to a deeper appreciation of molecular design and the intricacies involved in creating complex, functional molecules. This compound encapsulates the beauty and challenges of molecular chemistry!