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Thiosemicarbazide

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Identification
Molecular formula
C2H6N4S
CAS number
79-19-6
IUPAC name
3-(butylideneamino)isothiourea
State
State

At room temperature, thiosemicarbazide is in a solid state.

Melting point (Celsius)
179.00
Melting point (Kelvin)
452.00
Boiling point (Celsius)
260.00
Boiling point (Kelvin)
533.00
General information
Molecular weight
119.18g/mol
Molar mass
119.1820g/mol
Density
1.4360g/cm3
Appearence

Thiosemicarbazide appears as a white to light yellow crystalline solid.

Comment on solubility

Solubility of 3-(butylideneamino)isothiourea

The solubility of 3-(butylideneamino)isothiourea exhibits interesting characteristics that are important for its applications. This compound, particularly due to its functional groups, demonstrates varying solubility in different solvents.

Factors Affecting Solubility

Several factors impact the solubility of 3-(butylideneamino)isothiourea:

  • Polarity: The presence of polar functional groups may enhance solubility in polar solvents such as water or alcohols.
  • Hydrogen Bonding: The ability of the molecule to form hydrogen bonds is significant. Increased hydrogen bonding typically increases solubility in polar solvents.
  • Temperature: Generally, solubility increases with temperature, which is also relevant for this compound when dissolving in suitable solvents.

Expected Solubility Behavior

This compound is likely to be:

  • Moderately soluble in water due to its nitrogen functionalities.
  • More soluble in organic solvents such as ethanol or methanol.
  • Less soluble in nonpolar solvents like hexane.

The solubility is crucial to understand as it can influence the reactivity and interaction of 3-(butylideneamino)isothiourea in various chemical environments. Understanding these aspects can enhance its utility in laboratory or industrial applications.

Interesting facts

Interesting Facts about 3-(butylideneamino)isothiourea

3-(butylideneamino)isothiourea is a fascinating compound that presents a variety of intriguing attributes and applications, particularly in the realm of organic and medicinal chemistry. Here are some noteworthy points to consider:

  • Structure and Functionality: The compound features a unique structure that incorporates both a butylidene amino group and an isothiourea moiety, setting it apart from other compounds in its class. This specific architecture allows it to engage in diverse chemical reactions.
  • Biological Significance: Compounds containing isothiourea structures are often studied for their biological activities. Some of them have shown promising results in areas such as anti-cancer properties, antimicrobial activity, and enzyme inhibition.
  • Synthesis Pathways: The synthesis of 3-(butylideneamino)isothiourea can be achieved through various chemical methods, often involving the reaction of thiourea derivatives with suitable amines or aldehydes. This makes it a valuable synthetic intermediate in organic chemistry.
  • Research Applications: Chemists are particularly interested in isothiourea derivatives like this compound for their potential role as catalysts in organic reactions. They can facilitate a range of transformations, including nucleophilic substitutions and coupling reactions.
  • Theoretical Insights: Researchers utilize computational chemistry to predict the reactivity and stability of this compound. Understanding these properties allows scientists to anticipate its behavior in various environments, which is vital for its application in drug discovery.

In summary, 3-(butylideneamino)isothiourea is a compound enriched with potential and versatility. As scientists delve deeper into its properties and applications, it is likely to contribute to advancements in medicinal chemistry and related fields.