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Cefotaxime

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Identification
Molecular formula
C16H17N5O7S2
CAS number
63527-52-6
IUPAC name
3-(carbamoyloxymethyl)-7-methoxy-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
State
State

At room temperature, cefotaxime is in a solid state. It is stable under normal temperatures and pressures unless presented in aqueous solution form, which may be used for injection in medical applications.

Melting point (Celsius)
167.00
Melting point (Kelvin)
440.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
455.45g/mol
Molar mass
455.4490g/mol
Density
1.4600g/cm3
Appearence

Cefotaxime appears as a white to off-white crystalline powder. Its crystalline structure contributes to its solid state appearance.

Comment on solubility

Solubility of 3-(carbamoyloxymethyl)-7-methoxy-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

The solubility of 3-(carbamoyloxymethyl)-7-methoxy-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (C16H17N5O7S2) can be influenced by several factors, which makes it a subject of interest in both pharmaceutical and chemical research. Here are some key points to consider:

  • Nature of the compound: This compound contains functional groups such as carboxylic acids, aminos, and a thioether, which typically enhance solubility in polar solvents.
  • Polar and non-polar characteristics: The presence of both polar and non-polar groups can lead to a solubility profile that varies with the solvent chosen.
  • pH dependency: The solubility may change with pH, particularly due to the ionization of the carboxylic acid group at different pH levels.
  • Temperature effects: Generally, increased temperature can improve solubility for many compounds, and it is crucial to assess this phenomenon for better application and formulation purposes.

Overall, this compound likely exhibits moderate solubility in aqueous solutions but may require specific conditions or additives to enhance solubility for optimal use in practical applications. Maximizing the bioavailability of such compounds typically involves understanding and manipulating these solubility factors effectively.

Interesting facts

Interesting Facts about 3-(Carbamoyloxymethyl)-7-methoxy-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid

This complex compound, often referred to by its systematic name, showcases the intricate beauty of organic chemistry. Its structure embodies several fascinating features:

  • Unique Bicyclic Frame: This compound features a bicyclo structure, contributing to its distinctive properties. The fusion of rings can lead to interesting steric and electronic interactions, which may influence its reactivity and biological activity.
  • Functional Group Diversity: With multiple functional groups, including carbamoyl, thioether, and carboxylic acid moieties, this compound demonstrates remarkable versatility in chemical reactivity. Each group may impart different characteristics, making it a potential candidate for various applications.
  • Biological Relevance: The presence of an 8-oxo moiety suggests it may be biologically active, as such structures are often associated with antimicrobial or antitumor properties. Exploring this compound in medicinal chemistry could unveil potential therapeutic applications.
  • Thienyl Connection: The incorporation of a thienyl group adds a layer of complexity, as thiophene derivatives are known for their unique electronic properties and ability to participate in various chemical reactions. This could lead to interesting studies in organic synthesis.

Moreover, it’s worth noting that the field of chemistry often pursues compounds like this for their potential in drug design and development. As we further investigate compounds with such intricate structures, we may uncover new pathways, leading to advancements in therapeutics and material science. As one might say in chemistry, "The structure is the blueprint of function."

Overall, this compound exemplifies the rich landscape of chemical diversity and the insights that can be gained from studying intricate organic molecules.

Synonyms
56082-95-2
SCHEMBL7766649
DTXSID80860487
3-[(Carbamoyloxy)methyl]-7-methoxy-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid