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Betahistine Hydrochloride

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Identification
Molecular formula
C16H23ClNO2
CAS number
5638-76-6
IUPAC name
[3-carboxy-3-(1-naphthyl)propyl]-diethyl-ammonium;chloride
State
State

At room temperature, Betahistine hydrochloride is a solid. It is typically found in a crystalline form and readily dissolves in water, making it suitable for oral administration in pharmaceutical applications.

Melting point (Celsius)
158.00
Melting point (Kelvin)
431.15
Boiling point (Celsius)
225.00
Boiling point (Kelvin)
498.15
General information
Molecular weight
309.82g/mol
Molar mass
303.8290g/mol
Density
1.2360g/cm3
Appearence

Betahistine hydrochloride appears as a white or off-white crystalline powder. It is hygroscopic and may appear as fine particles with a slightly bitter taste.

Comment on solubility

Solubility of [3-carboxy-3-(1-naphthyl)propyl]-diethyl-ammonium;chloride

The solubility of the compound [3-carboxy-3-(1-naphthyl)propyl]-diethyl-ammonium;chloride is influenced by several key factors, given its dual functionality as both an ammonium salt and a carboxylic acid derivative.

  • Water Solubility: Typically, quaternary ammonium compounds exhibit good solubility in water due to their ionic nature. This compound’s chloride salt form enhances its solubility, making it readily soluble in aqueous solutions.
  • Organic Solubility: The presence of the naphthyl group introduces a non-polar character, often leading to moderate solubility in organic solvents like ethanol or acetone. It’s worthwhile to test solubility in different organic solvents.
  • Effect of pH: The solubility can be affected by the pH of the solution due to the carboxylic acid group, which can deprotonate under basic conditions, potentially increasing solubility in basic environments.

In conclusion, the solubility of [3-carboxy-3-(1-naphthyl)propyl]-diethyl-ammonium;chloride is characterized by:

  1. Good solubility in water
  2. Moderate solubility in certain organic solvents
  3. Dependency on pH conditions

Understanding these solubility principles is crucial for practical applications and further studies of this compound.

Interesting facts

Exploring [3-Carboxy-3-(1-Naphthyl)Propyl]-Diethyl-Ammonium Chloride

[3-Carboxy-3-(1-naphthyl)propyl]-diethyl-ammonium chloride is a fascinating compound that belongs to the category of quaternary ammonium salts. These compounds have garnered significant attention in various fields, particularly due to their unique properties and applications.

Key Features of the Compound

  • Quaternary Ammonium Structure: This compound features a nitrogen atom bound to four organic groups, providing it with potent amphiphilic characteristics.
  • Biological Applications: Quaternary ammonium compounds are often utilized as antimicrobial agents owing to their ability to disrupt microbial cell membranes.
  • Industrial Use: They are integral in various industrial processes, including surfactants, emulsifiers, and phase transfer catalysts.
  • Research Potential: The inclusion of the naphthyl group suggests potential applications in organic synthesis and drug discovery.

In addition, the presence of the carboxylic acid functional group endows this compound with the ability to interact with biological systems, making it a candidate for further research in drug formulation and delivery systems.

Interesting Quote

As the chemist John W. McCarty once said, "The art of chemistry is not in making measurements but in making molecules." This highlights the significance of understanding compounds like this one to innovate new solutions.

In summary, [3-Carboxy-3-(1-naphthyl)propyl]-diethyl-ammonium chloride is not just another compound; it represents a gateway to various applications across medical, industrial, and scientific fields. Its unique structure and properties make it a subject of great interest for both academic research and practical applications.

Synonyms
alpha-(2-(Diethylamino)ethyl)-1-naphthaleneacetic acid hydrochloride
6389-70-4
1-NAPHTHALENEACETIC ACID, alpha-(2-(DIETHYLAMINO)ETHYL)-, HYDROCHLORIDE