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Nafamostat

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Identification
Molecular formula
C19H23N2O2Cl2
CAS number
81525-10-2
IUPAC name
[3-carboxy-5-(dimethylammonio)-3-(1-naphthyl)pentyl]-dimethyl-ammonium;dichloride
State
State

At room temperature, Nafamostat is typically in a solid state as a crystalline powder.

Melting point (Celsius)
218.00
Melting point (Kelvin)
491.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
540.45g/mol
Molar mass
540.4510g/mol
Density
1.3055g/cm3
Appearence

Nafamostat appears as a white to off-white crystalline powder. It is hygroscopic, meaning it can absorb moisture from the air.

Comment on solubility

Solubility of [3-carboxy-5-(dimethylammonio)-3-(1-naphthyl)pentyl]-dimethyl-ammonium;dichloride

The solubility of the compound [3-carboxy-5-(dimethylammonio)-3-(1-naphthyl)pentyl]-dimethyl-ammonium; dichloride can be discussed from several perspectives:

Key Factors Affecting Solubility

  • Ionic nature: As a quaternary ammonium salt, its solubility in water can be quite high due to the ionic interactions.
  • Polarity: The presence of carboxylic acid and quaternary ammonium groups enhances its polarity, promoting solubility in polar solvents.
  • Temperature: Increased temperature generally encourages solubility, making the compound more soluble at elevated temperatures.

Predicted Solubility Characteristics

Given its ionic characteristics, it is likely to be:

  • Soluble in water: The polar nature due to ionic bonds suggests good solubility.
  • Less soluble in non-polar solvents: It may exhibit poor solubility in solvents like hexane or toluene.

Conclusion

In summary, the solubility of [3-carboxy-5-(dimethylammonio)-3-(1-naphthyl)pentyl]-dimethyl-ammonium; dichloride is influenced by its ionic nature, polarity, and temperature, making it highly soluble in polar solvents, particularly water.

Interesting facts

Interesting Facts about [3-Carboxy-5-(dimethylammonio)-3-(1-naphthyl)pentyl]-dimethyl-ammonium;dichloride

This compound, often referred to in research circles due to its unique structure, combines both ionic and organic characteristics, rendering it a fascinating subject of study. Here are some notable aspects:

  • Dual Functionality: The presence of both a carboxylate group and a quaternary ammonium group enables this compound to exhibit both hydrophilic and lipophilic properties, making it useful in various applications, including surfactants and drug delivery systems.
  • Structural Complexity: With the incorporation of the naphthyl ring, this compound showcases intriguing interactions that can affect its biological activity and overall reactivity in different environments.
  • Biological Relevance: Compounds with similar structures have been studied for their potential antibacterial and antifungal properties. Researchers are continuously investigating their efficacy in medicinal chemistry.
  • Potential in Material Science: This compound's unique properties may also be exploited in the design of new materials, particularly in the fields of nanotechnology and polymer science.
  • Research Opportunities: As a relatively complex compound, it offers pathways for studies in synthesis, reaction mechanisms, and interactions with biological systems.

In conclusion, the intriguing combination of this compound’s features not only attracts interest from chemists but also prompts interdisciplinary discussions spanning material science to pharmacology. As noted by a prominent chemist, "The beauty of chemistry lies in its ability to connect seemingly disparate elements into new, functional compounds."

Synonyms
1-Naphthaleneacetic acid, alpha,alpha-bis(2-(dimethylamino)ethyl)-, dihydrochloride
6394-74-7
alpha,alpha-Bis(2-(dimethylamino)ethyl)-1-naphthaleneacetic acid dihydrochloride