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4-Methoxychalcone

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Identification
Molecular formula
C10H9ClO2
CAS number
2252-44-0
IUPAC name
3-chloro-1-(4-methoxyphenyl)prop-2-en-1-one
State
State

At room temperature, 4-Methoxychalcone is a solid.

Melting point (Celsius)
75.00
Melting point (Kelvin)
348.15
Boiling point (Celsius)
370.80
Boiling point (Kelvin)
643.95
General information
Molecular weight
206.65g/mol
Molar mass
206.6530g/mol
Density
1.1670g/cm3
Appearence

4-Methoxychalcone is a yellow crystalline solid. The compound typically appears as needle-like crystals.

Comment on solubility

Solubility of 3-Chloro-1-(4-methoxyphenyl)prop-2-en-1-one

The solubility of 3-chloro-1-(4-methoxyphenyl)prop-2-en-1-one can be influenced by various factors, including temperature, solvent choice, and molecular interactions. Generally, the compound's solubility characteristics are as follows:

  • Solvent Polarity: As an organic compound, it is likely to be more soluble in non-polar to moderately polar solvents such as acetone, ethyl acetate, or chloroform.
  • Temperature Influence: Solubility tends to increase with temperature in many cases, which may enhance the dissolution of this compound in appropriate solvents.
  • Interactive Effects: The presence of the methoxy group may enhance solubility due to hydrogen bonding interactions with polar solvents.
  • Crystallinity: The physical form of the compound (amorphous vs crystalline) can also affect how well it dissolves; amorphous forms usually dissolve more readily.

It is essential to conduct experiments to determine the exact solubility in various solvents to establish a detailed profile. Understanding these aspects not only assists in practical applications but also aids in predicting the behavior of the compound in different environments.

Interesting facts

Interesting Facts about 3-chloro-1-(4-methoxyphenyl)prop-2-en-1-one

3-chloro-1-(4-methoxyphenyl)prop-2-en-1-one, often referred to as a compound of interest in medicinal and organic chemistry, has some remarkable characteristics that spark the curiosity of scientists and researchers alike. Here are some intriguing aspects:

  • Versatile Intermediate: This compound serves as a crucial intermediate in the synthesis of various bioactive molecules, making it a valuable asset in pharmaceutical research.
  • Analgesic Potential: Studies suggest that compounds similar in structure exhibit analgesic and anti-inflammatory properties, hinting at the potential therapeutic applications of this compound.
  • Chirality and Stereochemistry: The presence of the methoxy group positions this compound in a unique stereochemical environment, inviting scientists to explore its chiral properties which can influence its biological activity.
  • Fluorescent Properties: Some derivatives of this class show fluorescent behavior, making them useful in various analytical techniques including fluorescence microscopy and spectroscopy.
  • Environmental Relevance: Understanding the degradation pathways of such compounds contributes to the field of environmental chemistry, as they can pose risks in ecological contexts.

In conclusion, the study of 3-chloro-1-(4-methoxyphenyl)prop-2-en-1-one not only enhances our fundamental understanding of organic compounds but also opens up avenues for future research in therapeutic applications and environmental impact assessment. As stated by chemist Robert H. Grubbs, “The best chemists are not those who can work the hardest but those who can create the greatest imagination.”

Synonyms
C10H9ClO2
(alphaE)-beta-Chloro-4'-methoxyacrylophenone
SCHEMBL9224405