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3-Chloro-1-(4-methylpiperazin-1-yl)-6-nitroisoquinoline

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Identification
Molecular formula
C14H15ClN4O2
CAS number
641571-10-4
IUPAC name
3-chloro-1-(4-methylpiperazin-1-yl)-6-nitro-isoquinoline
State
State

At room temperature, it is typically a solid. Its solid state at room temperature is attributable to its high molar mass and the presence of intermolecular forces due to its aromatic rings and substituents.

Melting point (Celsius)
180.00
Melting point (Kelvin)
453.15
Boiling point (Celsius)
472.50
Boiling point (Kelvin)
745.60
General information
Molecular weight
307.75g/mol
Molar mass
307.7520g/mol
Density
1.3500g/cm3
Appearence

The compound appears as a solid with a yellowish color, typical of many nitro-substituted aromatic compounds. It may come in a crystalline form depending on the specific synthesis and purification methods used.

Comment on solubility

Solubility of 3-chloro-1-(4-methylpiperazin-1-yl)-6-nitro-isoquinoline

The solubility of 3-chloro-1-(4-methylpiperazin-1-yl)-6-nitro-isoquinoline can be influenced by various factors, including its chemical structure and the surrounding environment. Understanding these aspects can provide insights into its behavior in different solvents:

  • Polarity: Due to the presence of both polar and nonpolar functional groups, the compound may exhibit differing solubility in various solvents.
  • Aqueous Solubility: Like many isoquinoline derivatives, this compound may have limited solubility in water, which can be attributed to its hydrophobic regions.
  • Organic Solvents: It is likely to be more soluble in organic solvents such as ethanol or dimethyl sulfoxide (DMSO), which can better accommodate its organic structure.
  • Temperature Effect: Solubility often increases with temperature; thus, heating the solvent may enhance the dissolution of this compound.

In conclusion, while specific solubility data may be limited, the interactions of 3-chloro-1-(4-methylpiperazin-1-yl)-6-nitro-isoquinoline with various solvents highlight the importance of the chemical environment for studying its solubility properties. More detailed studies, including solubility testing under controlled conditions, would be essential for precise applications.

Interesting facts

Insights into 3-chloro-1-(4-methylpiperazin-1-yl)-6-nitro-isoquinoline

3-chloro-1-(4-methylpiperazin-1-yl)-6-nitro-isoquinoline is an intriguing compound that belongs to the class of isoquinoline derivatives, which are well-known for their diverse pharmacological applications. This compound, in particular, has garnered interest in medicinal chemistry due to its potential therapeutic benefits.

Key Features

  • Pharmacological Potential: Isoquinoline derivatives have been studied for their neuroprotective, anti-cancer, and anti-inflammatory properties.
  • Structural Diversity: The presence of both a chlorine and a nitro group within its structure introduces unique reactivity and interaction patterns, offering further exploration into how these modifications affect biological activity.
  • Piperazine Moiety: The 4-methylpiperazine component contributes to the compound's affinity for various receptors, enhancing its potential as a lead compound in drug development.

As a compound of interest in drug discovery, 3-chloro-1-(4-methylpiperazin-1-yl)-6-nitro-isoquinoline serves as a pertinent example of how modifying existing structures can lead to novel compounds with enhanced biological activities.

The investigation into this compound could reveal new insights in the treatment of neurological disorders, showcasing the ever-evolving landscape of medicinal chemistry. As research progresses, who knows what new therapeutic avenues will be uncovered?

Synonyms
19559-37-6
GO-230
3-chloro-1-(4-methylpiperazin-1-yl)-6-nitroisoquinoline
1-N-Methylpiperazine-2-chloro-4-nitroisoquinoline
3-Chloro-1-(4-methyl-1-piperazinyl)-5-nitroisoquinoline
DTXSID50941338
ISOQUINOLINE, 3-CHLORO-1-(4-METHYL-1-PIPERAZINYL)-5-NITRO-