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3-Chloro-2-nitrobenzoic acid

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Identification
Molecular formula
C7H4ClNO4
CAS number
1506-73-4
IUPAC name
3-chloro-2-nitro-benzoic acid
State
State

At room temperature, 3-Chloro-2-nitrobenzoic acid is in a solid state. It tends to form crystalline structures, which is typical for many aromatic carboxylic acids.

Melting point (Celsius)
157.50
Melting point (Kelvin)
430.65
Boiling point (Celsius)
305.70
Boiling point (Kelvin)
578.85
General information
Molecular weight
201.56g/mol
Molar mass
201.5520g/mol
Density
1.6795g/cm3
Appearence

3-Chloro-2-nitrobenzoic acid appears as a yellow crystalline solid. It is often encountered in powder form and can sometimes have an off-white hue depending on its purity and preparation method.

Comment on solubility

Solubility of 3-chloro-2-nitro-benzoic acid

3-chloro-2-nitro-benzoic acid, with the chemical formula C7H4ClN1O3, exhibits some intriguing solubility characteristics:

  • Solvent Dependency: This compound demonstrates variable solubility depending on the solvent used. It tends to be more soluble in organic solvents compared to water.
  • Hydrophilic Interactions: The presence of the carboxylic acid group (-COOH) enhances its ability to engage in hydrogen bonding, potentially increasing solubility in polar solvents like alcohols.
  • Temperature Effects: Like many compounds, solubility can increase with temperature. Hence, higher temperatures may enhance its solubility in both organic and aqueous mediums.
  • pH Influence: The degree of ionization of the carboxylic acid moiety is pH-dependent, impacting its solubility. At higher pH levels, the compound may ionize, becoming more soluble in water.

In summary, the solubility of 3-chloro-2-nitro-benzoic acid is influenced by several factors, including the nature of the solvent, temperature, and pH. Understanding these aspects can aid in the appropriate handling and application of this compound in various chemical processes.

Interesting facts

Interesting Facts about 3-Chloro-2-nitro-benzoic Acid

3-Chloro-2-nitro-benzoic acid is a fascinating compound that belongs to the family of nitrobenzoic acids. This compound plays a significant role in various chemical processes and applications. Here are some key points to consider:

  • Applications: It is widely used in the synthesis of various pharmaceuticals and agrochemicals. Its structural properties allow it to serve as a precursor in the development of biologically active compounds.
  • Reactivity: The presence of both –NO2 and –Cl groups makes this compound a powerful agent for electrophilic substitution reactions, facilitating the introduction of other functional groups.
  • Environmental Impact: As a derivative of benzoic acid, it demonstrates unique chemical behavior in various environmental conditions, which is essential for understanding its persistence and transformation in nature.
  • Biological Studies: Researchers are exploring its potential as an anti-inflammatory and anti-tumor agent, making it of interest in medicinal chemistry.
  • Structure-Activity Relationship (SAR): The positioning of the chlorine and nitro groups in the benzoic acid structure provides insights into SAR studies, helping scientists predict how structural changes can affect biological activity.

In the realm of synthetic organic chemistry, 3-chloro-2-nitro-benzoic acid is a valuable compound. Its unique functional groups and structural position offer intriguing possibilities for innovation and study.

"The molecule serves not just as a building block, but as a key to unlocking new chemical pathways and therapeutic perspectives."

Synonyms
3-CHLORO-2-NITROBENZOIC ACID
4771-47-5
Benzoic acid, 3-chloro-2-nitro-
EINECS 225-313-1
DTXSID70197259
DTXCID30119750
225-313-1
3-Chloro-2-nitrobenzoicacid
MFCD00007087
3-chloro-2-nitro-benzoic acid
Chlornitrobenzoesaure
chloro-2-nitrobenzoic acid
3-chloro2-nitrobenzoic acid
SCHEMBL206197
GEO-00754
TD1204
3-Chloro-2-nitrobenzoic acid, 97%
AKOS005254524
AB00833
AC-3191
CS-W002020
DS-0880
FC12112
BP-11473
SY005029
DB-051471
C0988
NS00031718
EN300-98788
InChI=1/C7H4ClNO4/c8-5-3-1-2-4(7(10)11)6(5)9(12)13/h1-3H,(H,10,11