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Chloramphenicol base

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Identification
Molecular formula
C11H12ClNO4
CAS number
56-75-7
IUPAC name
[(3-chloro-2,6-dimethoxy-benzoyl)-ethyl-amino] benzoate
State
State

This compound is generally found in a solid state at room temperature.

Melting point (Celsius)
150.00
Melting point (Kelvin)
423.15
Boiling point (Celsius)
450.00
Boiling point (Kelvin)
723.15
General information
Molecular weight
349.77g/mol
Molar mass
349.7700g/mol
Density
1.2980g/cm3
Appearence

Chloramphenicol base typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of [(3-chloro-2,6-dimethoxy-benzoyl)-ethyl-amino] benzoate

The solubility of [(3-chloro-2,6-dimethoxy-benzoyl)-ethyl-amino] benzoate can be influenced by various factors, including the compound’s molecular structure, polarity, and the solvent used. Generally, this compound may exhibit the following characteristics in terms of solubility:

  • Polar solvents: Due to the presence of polar functional groups, this compound is likely to be soluble in polar solvents such as water and alcohols. The capability to form hydrogen bonds can enhance solubility.

  • Non-polar solvents: Conversely, in non-polar solvents, the solubility may decrease significantly. The chlorinated and methoxy groups contribute to a supplementary polar character which may hinder dissolution in these media.

  • Temperature dependence: The solubility could also vary with temperature. Generally, increased temperature can improve solubility due to higher kinetic energy.

It is essential to conduct empirical tests to accurately assess the solubility of this compound under specific conditions, as the interaction with various solvents can lead to different solubility outcomes. As the famous proverb goes, "Like dissolves like," meaning that the polarity of the solvent is an essential factor in determining solubility.

Interesting facts

Interesting Facts about [(3-chloro-2,6-dimethoxy-benzoyl)-ethyl-amino] benzoate

[(3-chloro-2,6-dimethoxy-benzoyl)-ethyl-amino] benzoate is a fascinating compound with a plethora of interesting features that make it noteworthy in the field of chemistry and medicine. Here are some of the highlights:

  • Diverse Applications: This compound has potential applications in pharmaceuticals, particularly as an intermediate in synthesizing various biologically active compounds.
  • Structural Attributes: Its structure includes a benzoyl group, which often enhances the compound's reactivity and solubility, making it an excellent candidate for drug formulation.
  • Use in Research: Researchers are keenly interested in this compound due to its ability to serve as a model for understanding more complex interactions within biological systems.
  • Substituents Matter: The presence of both chloro and methoxy groups on the benzene ring may influence the compound's biological activity, as substitutions on aromatic systems can drastically alter their properties.
  • Synergistic Effects: The combination of the ethyl-amino moiety with the benzoyl backbone can yield synergistic effects, enhancing interaction with biological targets.

As we venture further into the world of organic chemistry and medicinal applications, compounds like [(3-chloro-2,6-dimethoxy-benzoyl)-ethyl-amino] benzoate remind us of the delicate balance between structure and function. The complexities surrounding this compound not only fuel scientific curiosity but also pave the way for innovative therapeutic agents. In the words of Antoine Lavoisier, "Nothing is lost, nothing is created, everything is transformed," emphasizing the transformative power of chemistry in developing new compounds with significant potential.

Synonyms
Benzoxamate
Acarmate
Artaban
Azomate
Citrazon
Benzoximate [BSI:ISO]
32TAI9ZK5N
NA-53M
NA-53
EINECS 249-439-1
BENZOXIMATE [ISO]
BRN 2783319
Benzoic acid, anhydride with 3-chloro-N-ethoxy-2,6-dimethoxybenzimidic acid
Benzoic acid anhydride with 3-chloro-N-ethoxy-2,6-dimethoxybenzenecarboximidic acid
RefChem:566441
DTXCID20810108
Benzoic acid anhydride with 3-chloro-N-ethoxy-2,6-dimethoxybenzenecarboximidic acid (9CI)
249-439-1
29104-30-1
3-Chloro-alpha-ethoxyimino-2,6-dimethoxybenzyl benzoate
benzoic 3-chloro-N-ethoxy-2,6-dimethoxybenzimidic anhydride
Benzoic acid, anhydride with 3-chloro-N-ethoxy-2,6-dimethoxybenzenecarboximidic acid
Benzoximate
CHEBI:38813
DTXSID8041660
ethyl O-benzoyl 3-chloro-2,6-dimethoxy-benzohydroximate
BENZOHYDROXAMIC ACID, O-BENZOYL-3-CHLORO-2,6-DIMETHOXY-N-ETHYL-
Benzoximat
67011-39-6
UNII-32TAI9ZK5N
SCHEMBL9806359
DTXSID001325320
NS00000095
C19021