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3-Chloro-4-hydroxybenzaldehyde

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Identification
Molecular formula
C7H5ClO2
CAS number
487-70-7
IUPAC name
3-chloro-4-hydroxy-benzaldehyde
State
State
At room temperature, 3-Chloro-4-hydroxybenzaldehyde is a solid. It has a crystalline nature and maintains stability in ambient conditions.
Melting point (Celsius)
92.00
Melting point (Kelvin)
365.15
Boiling point (Celsius)
281.00
Boiling point (Kelvin)
554.15
General information
Molecular weight
156.56g/mol
Molar mass
156.5600g/mol
Density
1.3810g/cm3
Appearence

3-Chloro-4-hydroxybenzaldehyde appears as a white to light yellow crystalline solid. It has a distinct aromatic odor typical of chlorinated aldehydes.

Comment on solubility

Solubility of 3-chloro-4-hydroxy-benzaldehyde

The solubility of 3-chloro-4-hydroxy-benzaldehyde, a compound featuring a hydroxyl (-OH) group, is influenced by several factors. Here are some key points to consider:

  • Polarity: The hydroxyl group contributes to the polarity of the molecule, generally enhancing its solubility in polar solvents, such as water.
  • Hydrogen Bonding: The ability to form hydrogen bonds means that 3-chloro-4-hydroxy-benzaldehyde can interact favorably with water molecules, potentially leading to improved solubility.
  • Solvent Type: While soluble in polar solvents, this compound may have limited solubility in non-polar solvents, reflecting typical behavior of similar aromatic compounds.
  • Temperature: Increased temperature often facilitates higher solubility levels, as it typically increases molecular motion and interactions with solvent molecules.

In summary, 3-chloro-4-hydroxy-benzaldehyde is likely to exhibit good solubility in polar solvents thanks to its hydroxyl functionality, while its solubility may decrease in non-polar environments. As always, experimental verification is essential for accurate solubility data.

Interesting facts

Interesting Facts about 3-Chloro-4-Hydroxy-Benzaldehyde

3-Chloro-4-hydroxy-benzaldehyde, also known as chlorohydroxybenzaldehyde, is a fascinating compound within the realm of organic chemistry. This compound stands out due to its unique structural features and its diverse applications in various fields.

Structural Significance

The presence of both a chlorine atom and a hydroxyl group makes 3-chloro-4-hydroxy-benzaldehyde a key player in the study of substituted aromatic compounds. The arrangement of these functional groups affects the compound's reactivity and interactions with other substances. Notably:

  • Chlorine Atom: Known for its ability to impart electrophilic character.
  • Hydroxyl Group: Provides the capacity for hydrogen bonding, which is critical in biological activities.

Applications and Uses

This compound is not just structurally interesting, but it also boasts a variety of applications:

  • Pharmaceuticals: Used as an intermediate in the synthesis of various medicinal compounds.
  • Agricultural Chemistry: Plays a role in the development of herbicides and pesticides.
  • Dyes and Pigments: Involved in dye production due to its reactivity and ability to form colored complexes.

Biological Importance

In the realm of biological sciences, 3-chloro-4-hydroxy-benzaldehyde has been studied for its potential as:

  • Antioxidant: Its structure suggests that it may scavenge free radicals, contributing to cellular health.
  • Antimicrobial Agent: Ongoing research explores its effectiveness against various pathogens.

In summary, the intriguing properties and potential of 3-chloro-4-hydroxy-benzaldehyde highlight its importance in both academic and practical chemistry. As a focus of research, it symbolizes the connection between molecular structure and function, leading to exciting discoveries in synthetic and applied chemistry.

Synonyms
3-CHLORO-4-HYDROXYBENZALDEHYDE
2420-16-8
NSC 85482
VGSOCYWCRMXQAB-UHFFFAOYSA-
DTXSID20178896
DTXCID80101387
Benzaldehyde, 3-chloro-4-hydroxy-(8CI)
Benzaldehyde, 3-chloro-4-hydroxy-(8CI)(9CI)
607-340-4
inchi=1/c7h5clo2/c8-6-3-5(4-9)1-2-7(6)10/h1-4,10h
vgsocywcrmxqab-uhfffaoysa-n
Benzaldehyde, 3-chloro-4-hydroxy-
MFCD00016981
4-hydroxy-3-chlorobenzaldehyde
3-chloro-4-hydroxy-benzaldehyde
NSC85482
NCIOpen2_001178
Benzaldehyde, 3-chloro-4-hydroxy- (8CI)(9CI)
3-chlor-4-hydroxybenzaldehyde
5-chloro-4-hyroxybenzaldehyde
SCHEMBL115626
5-chloro-4-hydroxybenzaldehyde
3-Chloro-4-hydroxy benzaldehyde
NSC-85482
STK199630
3-Chloro-4-hydroxybenzaldehyde, 97%
AKOS000104709
CS-W008817
FC55022
GS-3326
NCGC00340877-01
SY009040
C2183
NS00027585
EN300-49225
AB01333665-02
Z57313902