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3-Chloro-4-methylaniline

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Identification
Molecular formula
C7H8ClN
CAS number
95-74-9
IUPAC name
3-chloro-4-methyl-aniline
State
State

3-Chloro-4-methylaniline is typically found as a solid at room temperature.

Melting point (Celsius)
59.00
Melting point (Kelvin)
332.15
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.15
General information
Molecular weight
141.59g/mol
Molar mass
141.5880g/mol
Density
1.1630g/cm3
Appearence

3-Chloro-4-methylaniline is a crystalline solid that appears as off-white or light brown crystals. This compound has a distinct odor typical of aromatic amines.

Comment on solubility

Solubility of 3-Chloro-4-methyl-aniline

3-Chloro-4-methyl-aniline, with the chemical formula C7H8ClN, is a fascinating compound when it comes to solubility. The solubility characteristics of this compound can be summarized as follows:

  • Polar vs. Non-Polar: Due to the presence of the amino group (–NH2) and the chlorine atom, 3-chloro-4-methyl-aniline exhibits moderate polarity. This polarity generally enhances its solubility in polar solvents such as water.
  • Solubility in Water: The solubility of 3-chloro-4-methyl-aniline in water is relatively limited, suggesting that while it can dissolve to some extent, it is not highly soluble. This may be attributed to the hydrophobic methyl group, which tends to render some portions of the molecule less compatible with water.
  • Organic Solvents: On the other hand, this compound is expected to show good solubility in organic solvents such as ethanol, methanol, and acetone. The interaction between its non-polar regions and these solvents increases its overall solubility.

In conclusion, while 3-chloro-4-methyl-aniline is somewhat soluble in polar solvents, its solubility is generally stronger in non-polar or less polar environments. This characteristic can be crucial in applications where specific solvent interactions are desired.

Interesting facts

Interesting Facts about 3-Chloro-4-methyl-aniline

3-Chloro-4-methyl-aniline, also known as para-chloro-o-toluidine, is a fascinating chemical compound that belongs to the family of anilines. It exhibits a variety of intriguing characteristics and applications, making it an interesting subject for both chemists and students alike.

Key Features and Applications

  • Aromatic Amines: As an aromatic amine, 3-chloro-4-methyl-aniline plays a critical role in the production of dyes. It is a vital intermediate in the manufacturing of various azo dyes, which are widely used in textiles.
  • Pharmaceutical Relevance: The compound has potential applications in pharmaceutical synthesis and has been studied for its bioactive properties. It is essential to consider how modifications of this compound can lead to new therapeutic agents.
  • Industrial Use: 3-Chloro-4-methyl-aniline can also be used in producing rubber chemicals, pigments, and other organic compounds, showcasing its versatility in industrial applications.
  • Research Interest: The unique substitution pattern on the benzene ring makes it a subject of ongoing research for understanding reaction mechanisms and the development of new materials.

Safety Considerations

While 3-chloro-4-methyl-aniline has beneficial applications, it is crucial to handle this compound with care. It may pose various *health risks*, including:

  • Skin and eye irritation
  • Potential respiratory distress upon inhalation
  • Long-term exposure concerns related to carcinogenicity

The importance of utilizing proper safety protocols in laboratories when handling such compounds cannot be overstated. Always prioritize *protective gear* and adequate ventilation to minimize exposure.

A Final Thought

As a student or enthusiast in the field of chemistry, understanding compounds like 3-chloro-4-methyl-aniline enhances your knowledge of organic synthesis and materials science. The intricate world of functional groups and their behaviors opens a universe of possibilities for innovation and discovery in chemical research!

Synonyms
3-Chloro-4-methylaniline
95-74-9
3-CHLORO-P-TOLUIDINE
2-Chloro-4-aminotoluene
4-Amino-2-chlorotoluene
Benzenamine, 3-chloro-4-methyl-
3-Chloro-4-methylbenzenamine
3-Chloro-4-methylphenylamine
4-Methyl-3-chloroaniline
1-Amino-3-chloro-4-methylbenzene
p-Toluidine, 3-chloro-
NCI-C02040
DRC 1339
CCRIS 152
3-chloro-4-methyl-phenylamine
HSDB 2060
DRC 1347
EINECS 202-446-3
NSC 96620
UNII-32Y306W7BQ
BRN 0636511
DTXSID0020286
CHEBI:37824
3-chloro-4-toluidine
DKC 1347
MFCD00007773
NSC-96620
DTXCID60286
EC 202-446-3
32Y306W7BQ
4-12-00-01985 (Beilstein Handbook Reference)
3-?Chloro-?4-?methylaniline
3-Chloro-para-Toluidine
3-chloro-4-methyl aniline
CAS-95-74-9
3-CPT
Aniline, 3-chloro-4-methyl-
o-Chlor-p-toluidin
2Chloro4aminotoluene
4Amino2chlorotoluene
pToluidine, 3chloro
3Chloro4methylaniline
4Methyl3chloroaniline
827571-80-2
2-Chlor-4-aminotoluol
3Chloro4methylbenzenamine
3Chloro4methylphenylamine
3-chloro 4-methylaniline
2-chloro-4-amino-toluene
1Amino3chloro4methylbenzene
Benzenamine, 3chloro4methyl
WLN: ZR CG D1
3-chloranyl-4-methyl-aniline
MLS002303000
SCHEMBL349538
CHEMBL1374337
2-Chloro-4-aminotoluene, 98%
4-Amino-2-chlor-1-methylbenzol
3-Chloro-4-methylaniline, 98%
HMS3055G10
CS-M1324
NSC96620
STR02553
Tox21_201871
Tox21_302755
STK943762
AKOS000119158
4-AMINO-2-CHLOROTOLUENE[HSDB]
FC64322
4-AMINO-2-CHLOROTOLUENE [HSDB]
NCGC00091083-01
NCGC00091083-02
NCGC00256599-01
NCGC00259420-01
SMR001252231
TS-01846
DB-024297
NS00005824
EN300-18377
D77417
A845453
Q7602061
Z57127543
F2190-0474
3-Chloro-4-methylaniline, PESTANAL(R), analytical standard