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Olaparib

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Identification
Molecular formula
C24H23FN4O3
CAS number
763113-22-0
IUPAC name
3-chloro-6-(4-methyl-4-oxido-piperazin-4-ium-1-yl)-5H-benzo[b][1,4]benzodiazepine
State
State

At room temperature, Olaparib is typically in a solid state. It may be formulated into various forms including tablets or capsules for pharmaceutical use.

Melting point (Celsius)
99.00
Melting point (Kelvin)
372.15
Boiling point (Celsius)
370.10
Boiling point (Kelvin)
643.25
General information
Molecular weight
434.47g/mol
Molar mass
434.9180g/mol
Density
1.3902g/cm3
Appearence

Olaparib is often found as a white to pale yellow crystalline solid. It may vary in appearance based on the form and processing method used in its preparation.

Comment on solubility

Solubility of 3-chloro-6-(4-methyl-4-oxido-piperazin-4-ium-1-yl)-5H-benzo[b][1,4]benzodiazepine

The solubility of the compound 3-chloro-6-(4-methyl-4-oxido-piperazin-4-ium-1-yl)-5H-benzo[b][1,4]benzodiazepine (C24H23FN4O3) presents several intriguing characteristics:

  • Polarity: The presence of functional groups such as piperazine and the chloro moiety contributes to the overall polarity of the molecule, hinting at a potential for increased interaction with polar solvents.
  • Solvent Compatibility: Generally, compounds with similar polarities tend to dissolve better in one another. Therefore, this compound might exhibit good solubility in polar solvents like water or ethanol.
  • Influence of Ionic Forms: The structure contains a quaternary ammonium ion (piperazin-4-ium), which may enhance solubility in aqueous solutions, particularly if the pH of the solution favors its ionic form.
  • Temperature Dependence: It's important to note that solubility can be affected by temperature; generally, increased temperature can lead to increased solubility for many organic compounds.

In conclusion, while this compound is expected to have considerable solubility in polar solvents due to its unique structural features, conducting experimental solubility tests would provide definitive insights into its behavior in various solvents and conditions.

Interesting facts

Interesting Facts about 3-Chloro-6-(4-methyl-4-oxido-piperazin-4-ium-1-yl)-5H-benzo[b][1,4]benzodiazepine

3-Chloro-6-(4-methyl-4-oxido-piperazin-4-ium-1-yl)-5H-benzo[b][1,4]benzodiazepine is a fascinating compound belonging to the benzodiazepine class. This compound is known for its potential therapeutic properties, particularly in the realm of psychiatry and neurology. Here are some notable aspects of this intriguing chemical:

  • Structural Complexity: The compound features a complex structure with multiple functional groups, including a chlorine atom and a piperazine moiety. This complexity contributes to its unique chemical behavior.
  • Therapeutic Potential: As a benzodiazepine derivative, it may exhibit anxiolytic, anticonvulsant, and sedative effects, making it a compound of interest in medicinal chemistry. Research on its pharmacological effects can reveal more about its action mechanism.
  • Research Applications: This compound is often studied for its ability to interact with specific neurotransmitter receptors in the brain that regulate anxiety and mood, potentially leading to advancements in mental health treatments.
  • Noteworthy Derivative: The presence of a piperazine ring and an oxido group suggests intriguing properties that could enhance the compound's biological activity compared to other benzodiazepines.
  • Continued Exploration: With ongoing research into structural modifications, scientists continually seek to improve its efficacy and reduce side effects, making it a candidate for advanced therapeutic exploration.

As we delve deeper into the study of this compound, it is crucial to understand that its interaction with biological systems can be complex, and further studies will be needed to fully unravel its potential and applications in modern medicine.