Chloramphenicol | Solubility of Things

Identification

Molecular formula

C₁₁H₁₂ClNO₅

CAS number

56-75-7

IUPAC name

3-chloro-6-(hydroxymethyl)tetrahydropyran-2,4,5-triol

State

Chloramphenicol is generally found as a solid at room temperature.

Melting point (Celsius)

149.00

Melting point (Kelvin)

422.15

Boiling point (Celsius)

523.00

Boiling point (Kelvin)

796.15

General information

Molecular weight

323.13g/mol

Molar mass

323.1320g/mol

Density

1.7000g/cm³

Appearence

Chloramphenicol typically appears as a white to grayish-white crystalline powder. It is odorless and has a bitter taste.

Comment on solubility

Solubility of 3-chloro-6-(hydroxymethyl)tetrahydropyran-2,4,5-triol

The solubility of 3-chloro-6-(hydroxymethyl)tetrahydropyran-2,4,5-triol (C₁₁H₁₂ClNO₅) can be influenced by several factors including its molecular structure and functional groups. This compound features both hydroxymethyl and triol functional groups, which are known to enhance solubility in polar solvents due to hydrogen bonding capabilities.

Factors Affecting Solubility:

Hydroxyl Groups: The presence of multiple hydroxyl (–OH) groups dramatically increases solubility in water and other polar solvents.
Chlorine Atom: The chloro substituent may introduce some hydrophobic character; however, the overall impact is often outweighed by the polar hydroxyl groups.
Structural Conformation: The cyclic nature of tetrahydropyran can influence how the molecule interacts with solvents, potentially enhancing solubility through favorable interactions.

As a general observation, compounds with higher polarity tend to dissolve better in polar solvents. Therefore, it's reasonable to expect that 3-chloro-6-(hydroxymethyl)tetrahydropyran-2,4,5-triol would exhibit notable solubility in aqueous solutions as well as other polar solvents.

In summary, the interplay of various functional groups within C₁₁H₁₂ClNO₅ suggests a significant potential for **solubility** in water and similar solvents, driven largely by its ability to form hydrogen bonds.

Interesting facts

Interesting Facts about 3-chloro-6-(hydroxymethyl)tetrahydropyran-2,4,5-triol

3-chloro-6-(hydroxymethyl)tetrahydropyran-2,4,5-triol is an intriguing compound that showcases the complexity of organic chemistry. Here are some fascinating aspects to consider:

Structural diversity: This compound features a sugar-like structure that includes both hydroxymethyl and chloro functional groups. The presence of multiple stereocenters enhances the potential for stereoisomerism, making it a subject of interest in stereochemistry.
Biological significance: Compounds with similar structures have been studied for their potential biological activities. This includes applications in pharmaceuticals, where structural modifications can lead to compounds with enhanced biological efficacy.
Applications in synthesis: Its unique structure makes it a versatile intermediate for synthesizing other complex organic molecules. The hydroxymethyl group can serve as a key site for further chemical transformations, allowing chemists to explore various pathways for new compound development.
Chlorine's role: The presence of the chlorine atom is not merely decorative; it can significantly influence the chemical reactivity and stability of the compound. Chlorinated compounds often exhibit unique properties, including improved reactivity in certain chemical reactions.
Potential research implications: The study of compounds like 3-chloro-6-(hydroxymethyl)tetrahydropyran-2,4,5-triol opens doors to discovering new materials or drugs. Research in this area could lead to breakthroughs in medical chemistry and materials science.

In summary, 3-chloro-6-(hydroxymethyl)tetrahydropyran-2,4,5-triol exemplifies the complexity and utility of organic compounds in scientific research. Its fascinating structure and potential applications make it an important topic of study within the field.

Synonyms

2-Chloro-DG

SCHEMBL10345056

PD034516