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Zotepine

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Identification
Molecular formula
C18H18ClNOS
CAS number
26615-21-4
IUPAC name
3-chloro-9-(1-methyl-4-piperidylidene)thioxanthene 10-oxide
State
State

At room temperature, zotepine is typically a solid, presented as a crystalline powder.

Melting point (Celsius)
187.00
Melting point (Kelvin)
460.15
Boiling point (Celsius)
449.80
Boiling point (Kelvin)
722.95
General information
Molecular weight
327.87g/mol
Molar mass
327.8430g/mol
Density
1.2600g/cm3
Appearence

Zotepine appears as a pale yellow crystalline powder. It is known for its distinctive chemical structure that includes a thioxanthene core ring substituted with a chlorine atom and a piperidylidene moiety.

Comment on solubility

Solubility of 3-chloro-9-(1-methyl-4-piperidylidene)thioxanthene 10-oxide

The solubility of 3-chloro-9-(1-methyl-4-piperidylidene)thioxanthene 10-oxide in various solvents can greatly impact its applications in both research and industry. Understanding its solubility is crucial for efficient utilization in processes such as pharmaceutical formulation and material science.

Key Solubility Characteristics:

  • Solvent Dependence: This compound shows varying solubility in different solvents, typically favoring organic solvents over aqueous ones.
  • Polar and Non-polar Solvents: It is more soluble in non-polar and slightly polar organic solvents due to the hydrophobic nature of its aromatic structure.
  • Temperature Effects: Like many chemical compounds, solubility may increase with temperature, making it essential to consider thermal conditions during usage.
  • Hydrolytic Stability: Given the presence of chlorine and the thioxanthene ring, hydrolytic stability could influence solubility when in contact with water; thus, its solubility in aqueous environments is limited.

It is important to remember that the interaction of the solute with the solvent plays a pivotal role in determining solubility. Factors such as polarity, molecular size, and temperature can significantly affect how easily this compound dissolves.

In summary, the solubility of 3-chloro-9-(1-methyl-4-piperidylidene)thioxanthene 10-oxide is contextually dependent, emphasizing the need for careful selection of solvents in applications to achieve desired results.

Interesting facts

Interesting Facts about 3-chloro-9-(1-methyl-4-piperidylidene)thioxanthene 10-oxide

3-chloro-9-(1-methyl-4-piperidylidene)thioxanthene 10-oxide is a fascinating compound that garners attention due to its unique structure and potential applications in various fields. Here are some notable aspects to consider:

  • Structural Composition: This compound contains a thioxanthene core, which is known for its diverse chemical properties and ability to interact with biological systems.
  • Biological Activity: Compounds containing a thioxanthene scaffold have been studied for their potential in neuroleptic activity, making them significant in pharmacology for antipsychotic applications.
  • Chlorination Consequences: The presence of a chlorine atom in this compound can influence its reactivity and biological interactions, potentially enhancing its efficacy or altering its metabolic profile.
  • Piperidine Influence: The inclusion of a 1-methyl-4-piperidylidene group adds to the complexity and may contribute significantly to the compound's pharmacodynamics, affecting how it interacts with receptors in the central nervous system.
  • Research Potential: As a researcher, one might find this compound interesting for studies in medicinal chemistry, especially related to designing next-generation pharmaceuticals.

In summary, 3-chloro-9-(1-methyl-4-piperidylidene)thioxanthene 10-oxide serves as a striking example of how subtle changes in molecular structure can lead to variations in function and application. Its complex interplay of components provides a rich avenue for exploration in both basic and applied science.

Synonyms
9V119IY0RM
UNII-9V119IY0RM
3-Chloro-9-(N-methyl-4-piperidylidene)thioxanthene 10-oxide
314-00-1
3-Chloro-9-(1-methylpiperidylidene-4)thioxanthene-10-oxide
Piperidine, 4-(3-chloro-10-oxido-9H-thioxanthen-9-ylidene)-1-methyl-
Piperidine, 4-(3-chloro-9H-thioxanthen-9-ylidene)-1-methyl-, S-oxide