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3-Chloro-N-(2,2-difluoroethyl)aniline

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Identification
Molecular formula
C8H8ClF2N
CAS number
474706-02-6
IUPAC name
3-chloro-N-(2,2-difluoroethyl)aniline
State
State

This compound is typically a liquid at room temperature.

Melting point (Celsius)
9.00
Melting point (Kelvin)
282.15
Boiling point (Celsius)
219.00
Boiling point (Kelvin)
492.15
General information
Molecular weight
191.61g/mol
Molar mass
191.6120g/mol
Density
1.2880g/cm3
Appearence

3-Chloro-N-(2,2-difluoroethyl)aniline appears as a colorless to pale yellow liquid at room temperature. It may darken upon exposure to air or light.

Comment on solubility

Solubility of 3-chloro-N-(2,2-difluoroethyl)aniline

The solubility of 3-chloro-N-(2,2-difluoroethyl)aniline can be quite intricate, as it is influenced by various factors including temperature, pH, and the presence of other solutes. Generally speaking, this compound exhibits the following solubility characteristics:

  • Water Solubility: It tends to have limited solubility in water due to the presence of the hydrophobic aromatic ring which can hinder interaction with polar water molecules.
  • Organic Solubility: It is more soluble in organic solvents such as ethanol or acetone, where its hydrophobic interactions can prevail, facilitating better solvation.
  • Temperature Dependence: Like many organic compounds, its solubility may increase with rising temperatures, as higher kinetic energy can help overcome intermolecular forces.

One can consider the principle of "like dissolves like," which emphasizes that the solubility of a compound in a particular solvent largely depends on the polarity of both the compound and the solvent. In the case of 3-chloro-N-(2,2-difluoroethyl)aniline, it can be concluded that:

  • It is likely to dissolve better in non-polar or slightly polar solvents rather than in highly polar solvents such as water.
  • The fluorinated group may enhance some unique solubility profiles, so experimenting with a variety of solvents is advisable for specific applications.

Thus, understanding the solubility of this compound is crucial for its applications in various fields, where solvent selection can play a vital role in its effectiveness and behavior.

Interesting facts

Interesting Facts about 3-chloro-N-(2,2-difluoroethyl)aniline

The compound 3-chloro-N-(2,2-difluoroethyl)aniline is an intriguing member of the aniline family, known for its versatile chemical properties and applications in various fields.

Chemical Structure and Properties

This compound features a chlorinated aniline core, which makes it relevant in organic synthesis. The presence of both a chlorine atom and a difluoroethyl group contributes to its unique reactivity and polarity, allowing for a wide range of chemical interactions.

Applications

  • Pesticide Development: The fluorinated segment may enhance its effectiveness in agricultural applications, making it potentially useful in the synthesis of crop protection agents.
  • Pharmaceutical Research: Compounds similar to this structure are often explored in drug discovery due to their biological activity and ability to interact with target proteins.
  • Dye Manufacturing: Anilines are often employed in the production of dyes and pigments; thus, this compound might serve as an intermediate in synthetic pathways.

Environmental Considerations

As with many halogenated compounds, the environmental impact of 3-chloro-N-(2,2-difluoroethyl)aniline is a key consideration in research and application. Fluorinated compounds tend to have intriguing, yet sometimes problematic, environmental behaviors, specifically regarding persistence and bioaccumulation.

Quote to Consider

"The journey of a compound from the laboratory to real-world applications is often paved with unexpected challenges and discoveries!"

In conclusion, 3-chloro-N-(2,2-difluoroethyl)aniline stands out with its unique structure and promising applications, making it a worthy subject of study in both academic and industrial settings.

Synonyms
3-chloro-N-(2,2-difluoroethyl)aniline
331-54-4
ANILINE, m-CHLORO-N-(2,2-DIFLUOROETHYL)-
m-Chloro-N-(2,2-difluoroethyl)aniline
BRN 3249275
DTXSID50186767
4-12-00-01139 (Beilstein Handbook Reference)
DTXCID90109258
QSLIBRQKKASYQF-UHFFFAOYSA-N
AAA33154
AKOS010145638
CS-0230431
EN300-103870
G54772
Z608352346