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3-Chloroisoxazole-5-carboxylic acid

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Identification
Molecular formula
C4H2ClNO3
CAS number
38059-55-7
IUPAC name
3-chloroisoxazole-5-carboxylic acid
State
State
At room temperature, 3-Chloroisoxazole-5-carboxylic acid exists as a solid.
Melting point (Celsius)
130.00
Melting point (Kelvin)
403.15
Boiling point (Celsius)
225.00
Boiling point (Kelvin)
498.15
General information
Molecular weight
161.50g/mol
Molar mass
161.5000g/mol
Density
1.6000g/cm3
Appearence

3-Chloroisoxazole-5-carboxylic acid appears as a crystalline solid. The crystals are usually white to off-white in color.

Comment on solubility

Solubility of 3-chloroisoxazole-5-carboxylic acid

3-chloroisoxazole-5-carboxylic acid is a compound that exhibits some interesting characteristics regarding its solubility. Generally, the solubility of this compound can be influenced by various factors including pH, temperature, and the presence of other solvents.

Here are some key points to consider:

  • Solvent Type: 3-chloroisoxazole-5-carboxylic acid tends to be more soluble in polar solvents such as water, ethanol, and dimethyl sulfoxide (DMSO).
  • pH Dependence: The acidity of the carboxylic group can lead to increased solubility in basic solutions, as it can ionize to form a carboxylate anion.
  • Temperature Effects: Typically, solubility increases with temperature; thus, heating may enhance the dissolution of this compound.

As a rule of thumb, "like dissolves like" plays a significant role here, highlighting that polar substances will interact favorably with other polar solvents. Therefore, understanding the nature of the solvents involved is crucial when contemplating the solubility of 3-chloroisoxazole-5-carboxylic acid.

In conclusion, while this compound shows reasonable solubility in water and alcohols, conditions such as temperature and pH must be optimized to achieve the best results.

Interesting facts

Interesting Facts about 3-chloroisoxazole-5-carboxylic acid

3-chloroisoxazole-5-carboxylic acid is an intriguing compound with various applications and unique properties that make it a subject of interest in the field of chemistry. Here are some fascinating insights:

  • Isoxazole Structure: This compound belongs to the isoxazole family, which is characterized by a five-membered ring containing an oxygen and a nitrogen atom. The presence of both a carboxylic acid group and a chlorine atom enhances its reactivity.
  • Biological Relevance: Compounds with isoxazole rings have been reported to possess antimicrobial and antifungal properties. They are often investigated for their potential use in pharmaceuticals.
  • Synthesis Routes: The synthesis of 3-chloroisoxazole-5-carboxylic acid often involves a multi-step process that may include cyclization reactions and strategic functional group transformations. This synthesis showcases the beauty of organic chemistry and the creativity of chemists.
  • Versatile Reactivity: The presence of both a carboxylic acid and a chlorine substituent allows for diverse chemical reactivity, paving the way for the formation of various derivatives that can be used in different contexts, such as drug development and agricultural chemicals.
  • Research Applications: Scientists are exploring the use of this compound in developing new materials and catalytic processes, highlighting its potential in advancing modern chemistry and technology.

In summary, 3-chloroisoxazole-5-carboxylic acid is more than just a chemical formula; it represents a world of possibilities in scientific inquiry and practical applications. As the landscape of chemistry continues to evolve, this compound stands as a testament to the innovative spirit of the field.

Synonyms
3-Chloroisoxazole-5-carboxylic acid
20724-56-5
3-chloro-1,2-oxazole-5-carboxylic acid
5-ISOXAZOLECARBOXYLIC ACID, 3-CHLORO-
BRN 0879290
DTXSID80174798
DTXCID6097289
854-697-9
RefChem:536493
3-Chloro-5-isoxazolecarboxylic acid
MFCD01716783
SCHEMBL6050354
IDKGQUZZCFRJHC-UHFFFAOYSA-N
3-Chloroisoxazole-5-carboxylicacid
ALBB-014179
BBL029454
SBB074354
STL259768
AKOS005174283
SY148429
VS-09243
DB-105487
CS-0449767
EN300-127789
H30625