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3-(Chloromethyl)pyridine hydrochloride

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Identification
Molecular formula
C6H7Cl2N
CAS number
6959-47-3
IUPAC name
3-(chloromethyl)pyridine;hydrochloride
State
State

At room temperature, 3-(chloromethyl)pyridine hydrochloride is typically in a solid crystalline state.

Melting point (Celsius)
210.00
Melting point (Kelvin)
483.15
Boiling point (Celsius)
314.30
Boiling point (Kelvin)
587.45
General information
Molecular weight
162.04g/mol
Molar mass
162.0470g/mol
Density
1.2750g/cm3
Appearence

The compound typically appears as a white to off-white crystalline powder. It may exhibit slight hygroscopic properties, absorbing moisture from the air.

Comment on solubility

Solubility of 3-(chloromethyl)pyridine;hydrochloride

The solubility of 3-(chloromethyl)pyridine;hydrochloride is an interesting subject due to its ionic nature influenced by the presence of the hydrochloride group. Here are some key points regarding its solubility:

  • Polarity: As a salt, the compound exhibits significant polarity, which generally leads to higher solubility in polar solvents.
  • Water Solubility: It is typically soluble in water due to the ability of the hydrochloride ion to interact favorably with water molecules.
  • Alcohol Solubility: The compound may also show solubility in various organic solvents, particularly in alcohols, where hydrogen bonding can occur.
  • Temperature Effects: The solubility of salts like this one often increases with temperature, meaning heating the solution could enhance its dissolution.

Overall, the solubility profile of 3-(chloromethyl)pyridine;hydrochloride can be summarized as favorable in polar solvents, making it a useful compound in various applications where solubility is a critical factor. As often stated in chemistry, "like dissolves like," and in this case, we see the truth of this adage in the compound’s interactions with water and other polar solvents.

Interesting facts

Interesting Facts about 3-(Chloromethyl)pyridine; Hydrochloride

3-(Chloromethyl)pyridine; hydrochloride is an intriguing compound that exhibits both chemical and biological significance. As a quaternary ammonium compound, it possesses a range of fascinating properties and applications. Here are some noteworthy aspects:

  • Versatile Intermediates: This compound serves as an important intermediate in the synthesis of various heterocyclic compounds, which are crucial in medicinal chemistry.
  • Pharmacological Potential: Research has indicated the potential of pyridine derivatives like 3-(chloromethyl)pyridine in developing new pharmaceuticals due to their ability to interact with biological targets.
  • Industrial Applications: Beyond just pharmaceuticals, it finds use in the production of pesticides, herbicides, and other agrochemicals, showcasing its versatility in the industry.
  • Reactivity: The presence of the chloromethyl group makes this compound reactive, allowing for coupling reactions and further derivatization, which is highly valued in organic synthesis.
  • Biochemical Significance: Some studies suggest that compounds with a pyridine ring may have roles in biological systems, influencing enzyme activities and metabolic pathways.

In summary, 3-(chloromethyl)pyridine; hydrochloride is more than just a chemical entity; it is a potentially valuable compound with diverse applications in agricultural and pharmaceutical sectors. Its unique characteristics continue to be an area of research interest, underscoring the compound's role in advancing science and industry.

Synonyms
3-(CHLOROMETHYL)PYRIDINE HYDROCHLORIDE
6959-48-4
3-Picolyl chloride hydrochloride
3-Chloromethylpyridine hydrochloride
3-(Chloromethyl)pyridine HCl
3-Pyridylmethyl chloride hydrochloride
Pyridine, 3-(chloromethyl)-, hydrochloride
CCRIS 140
NCI-C03838
3-(Chloromethyl)pyridinium chloride
BQA8FYP4YN
HSDB 4121
EINECS 230-150-4
NSC 66482
3-(Chloromethyl) pyridine, hydrochloride
DTXSID6020309
NSC-66482
Pyridine, 3-chloromethyl-, hydrochloride
DTXCID00309
3-chloromethyl pyridine hydrochloride
3-(CHLOROMETHYL)PYRIDINE MONOHYDROCHLORIDE
(PYRIDIN-3-YL)METHYL CHLORIDE HYDROCHLORIDE
3-(CHLOROMETHYL)PYRIDINE HYDROCHLORIDE [HSDB]
PYRIDINE, 3-(CHLOROMETHYL)-, HYDROCHLORIDE (1:1)
3(Chloromethyl)pyridine HCl
3Pyridylmethyl chloride hydrochloride
3(Chloromethyl) pyridine, hydrochloride
Pyridine, 3(chloromethyl), hydrochloride
3-(Chloromethyl)pyridine.HCl
3-Chloromethyl-pyridine hydrochloride
MFCD00012818
3-(chloromethyl)pyridine;hydrochloride
3-(Chloromethyl)pyridine, HCl
CAS-6959-48-4
UNII-BQA8FYP4YN
(Pyridin-3-yl)methyl Chloride Hydrochloride; 3-(Chloromethyl)pyridine Monohydrochloride; 3-Picolyl Chloride Hydrochloride; 3-Pyridylmethyl Chloride Hydrochloride
3-(Chloromethyl) Pyridine Hydrochloride
SCHEMBL18044
3-Picolylchloride hydrochloride
WLN: T6NJ C1G &GH
CHEMBL3182495
3-chloromethyl-pyridine HCl salt
3-chloromethyl pyridinium chloride
BCP31279
NSC66482
3-pyridylmethylchloride hydrochloride
Tox21_202370
Tox21_302887
3-(chloromethyl)pyridine-hydrochloride
AKOS005257580
3-pyridyl-methyl chloride hydrochloride
AC-2905
CS-W003964
3-(chloro-methyl)pyridine hydrochloride
3-(chloromethyl)-pyridine hydrochloride
3-(Chloromethyl)pyridine, hydrochloride
3-chloromethyl-pyridine hydrogen chloride
NCGC00256478-01
NCGC00259919-01
3-(Chloromethyl)-pyridinium hydrochloride
3-chloromethylpyridine, hydrochloride salt
AS-14493
(pyridin-3-yl)methylchloride hydrochloride
DB-000472
3-(Chloromethyl)pyridine hydrochloride, 96%
3-(CHLOROMETHYL)PYRIDINEHYDROCHLORIDE
C0825
EN300-21771
Q27274816
F2145-0703
3-Chloromethylpyridine hydrochloride (3-Picolylchloride hydrochloride)