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(3-Chlorophenyl)urea

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Identification
Molecular formula
C7H7ClN2O
CAS number
102-41-4
IUPAC name
(3-chlorophenyl)urea
State
State

At room temperature, (3-Chlorophenyl)urea is typically found in a solid state.

Melting point (Celsius)
203.00
Melting point (Kelvin)
476.15
Boiling point (Celsius)
292.00
Boiling point (Kelvin)
565.15
General information
Molecular weight
171.60g/mol
Molar mass
171.6000g/mol
Density
1.3000g/cm3
Appearence

(3-Chlorophenyl)urea is a crystalline solid that appears as white or off-white crystals or powder.

Comment on solubility

Solubility of (3-chlorophenyl)urea

(3-chlorophenyl)urea is a compound that exhibits distinctive solubility characteristics, making it of interest in various chemical applications. Its solubility can be influenced by several factors, leading to varied behavior in different solvent systems.

Solubility Characteristics

  • Water Solubility: (3-chlorophenyl)urea has moderate solubility in water, which can be attributed to the presence of the urea group that allows for hydrogen bonding.
  • Solubility in Organic Solvents: It demonstrates higher solubility in organic solvents such as ethanol and acetone, making it useful in organic synthesis.
  • Temperature Dependence: The solubility tends to increase with an increase in temperature. Thus, heating solvents may facilitate dissolution.

It is essential to keep in mind that the presence of the 3-chlorophenyl group can create hydrophobic interactions, which may limit solubility in highly polar solvents while enhancing it in non-polar environments. As a result, the solubility of (3-chlorophenyl)urea can be summarized by the following points:

  1. Moderately soluble in water.
  2. Highly soluble in ethanol and other organic solvents.
  3. Temperature-dependent solubility.

In conclusion, understanding the solubility properties of (3-chlorophenyl)urea aids researchers in predicting its behavior in varied chemical environments, enriching its applicability in pharmaceutical and chemical processes.

Interesting facts

Interesting Facts about (3-Chlorophenyl)urea

(3-Chlorophenyl)urea is a compound worth exploring due to its diverse applications and intriguing chemical characteristics. Here are some key facts:

  • Organic Chemistry Relevance: This compound falls under the category of urea derivatives, which are essential in organic synthesis. They often serve as intermediates in the production of pharmaceuticals and agrochemicals.
  • Biological Activity: Compounds similar to (3-chlorophenyl)urea have been studied for their biological properties, including their potential as herbicides and fungicides. Their mechanism of action often targets critical biological pathways in plants and fungi.
  • Substituent Effects: The presence of the chlorine atom in the para position influences the reactivity and properties of the compound. Halogens are known to enhance the lipophilicity of organic molecules, which can affect their bioavailability and overall efficacy.
  • Research Applications: This compound serves as a valuable tool in academic research, particularly in studies focusing on the relationship between structure and activity (SAR) in drug development. Understanding how modifications to the urea moiety affect biological interactions can lead to the design of more effective agents.
  • Environmental Considerations: As with many chemical substances, understanding the environmental impact of (3-chlorophenyl)urea is crucial. Research into its degradation pathways and toxicity is essential for ensuring safe usage in agricultural practices.

In conclusion, (3-chlorophenyl)urea exemplifies the importance of small organic molecules in the field of chemistry. The intersection of its chemical structure with biological functions presents vast opportunities for innovation in both scientific research and practical applications.

Synonyms
3-CHLOROPHENYLUREA
1967-27-7
meta-Chlorophenylurea
Urea, (3-chlorophenyl)-
NSC 41826
DTXSID90173338
DTXCID6095829
622-395-4
(3-chlorophenyl)urea
m-Chlorophenylurea
1-(3-chlorophenyl)urea
N-(3-chlorophenyl)urea
Urea,N-(3-chlorophenyl)-
CHEMBL131289
NSC-41826
N-[3-chlorophenyl]urea
MFCD00025416
3-(3-chlorophenyl)urea
(3-Chloro-phenyl)-urea
Urea, (m-chlorophenyl)-
YM6G7RE55S
Urea, N-(3-chlorophenyl)-
SCHEMBL167193
PPCUBWWPGYHEJE-UHFFFAOYSA-N
BAA96727
NSC41826
BDBM50053600
STK369217
AKOS000144817
BS-25446
DB-044939
CS-0206434
EN300-176931
G22442
Z166687084