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Trihexyphenidyl

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Identification
Molecular formula
C20H31NO
CAS number
144-11-6
IUPAC name
(3-cyclohexyl-3-hydroxy-3-phenyl-propyl)-triethyl-ammonium
State
State

At room temperature, trihexyphenidyl is in a solid state, typically found as a powder or crystalline form.

Melting point (Celsius)
100.00
Melting point (Kelvin)
373.15
Boiling point (Celsius)
285.00
Boiling point (Kelvin)
558.15
General information
Molecular weight
337.56g/mol
Molar mass
337.5640g/mol
Density
1.0590g/cm3
Appearence

Trihexyphenidyl appears as a white crystalline powder. It is usually odorless and has a bitter taste. The compound is not very soluble in water but can be dissolved in alcohol and chloroform.

Comment on solubility

Solubility of (3-cyclohexyl-3-hydroxy-3-phenyl-propyl)-triethyl-ammonium

The solubility of (3-cyclohexyl-3-hydroxy-3-phenyl-propyl)-triethyl-ammonium is influenced by its unique structure and the presence of both hydrophobic and hydrophilic groups.

Factors Affecting Solubility:

  • Hydrophilic Moieties: The triethyl-ammonium group can enhance solubility in polar solvents, particularly water, due to its ionic nature.
  • Hydrophobic Characteristics: The cyclohexyl and phenyl groups contribute to hydrophobic interactions, potentially decreasing solubility in aqueous environments.
  • Temperature: As with many compounds, increased temperature can improve solubility as it increases molecular motion and reduces intermolecular forces.

Overall, the solubility of this compound may vary significantly depending on the solvent used. It tends to be more soluble in:

  • Polar solvents (e.g., water, methanol)
  • Non-polar solvents (e.g., hexane) might show limited solubility due to the hydrophobic characteristics.

In practice, solubility should be assessed experimentally under various conditions to determine practical applications and efficacy. As noted in solubility studies, "The balance between hydrophobic and hydrophilic properties dictates solvent interactions."


Interesting facts

Interesting Facts about (3-cyclohexyl-3-hydroxy-3-phenyl-propyl)-triethyl-ammonium

(3-cyclohexyl-3-hydroxy-3-phenyl-propyl)-triethyl-ammonium is a fascinating compound that exhibits unique properties and applications. Here are some interesting aspects:

  • Quaternary Ammonium Compound: This compound belongs to the class of quaternary ammonium salts, which are known for their significant role in various industries such as pharmaceuticals, cosmetics, and antimicrobial agents.
  • Structure Diversity: The presence of both cyclohexyl and phenyl groups in its structure contributes to its diverse chemical characteristics and potential utility in organic synthesis and medicinal chemistry.
  • Hydroxyl Group: The hydroxyl (-OH) functional group indicates that this compound can engage in hydrogen bonding, which potentially enhances its solubility in polar solvents and its reactivity in biological systems.
  • Biological Significance: Research suggests that quaternary ammonium compounds can exhibit antimicrobial properties, which makes them valuable in the development of disinfectants and antiseptics.
  • Potential Applications: Given its complex structure, this compound may prove useful as an intermediate in chemical reactions or as a ligand in catalysis, highlighting its versatility in synthetic organic chemistry.
  • Research Opportunities: The study of such compounds is ongoing, with scientists exploring their mechanisms, reactivity, and potential therapeutic effects in various biological systems.

In summary, the unique structural features and functional capabilities of (3-cyclohexyl-3-hydroxy-3-phenyl-propyl)-triethyl-ammonium make it a compelling subject of research and exploration within the field of chemistry. It exemplifies the complex interplay between molecular structure and application.

Synonyms
Tridihexethyl
Propethonum
60-49-1
Tridihexethyl ion
Tridihexethyl cation
CHEBI:9701
7HE50A367X
TRIDIHEXETHYL [VANDF]
TRIDIHEXETHYL [WHO-DD]
DTXSID0048553
3-cyclohexyl-N,N,N-triethyl-3-hydroxy-3-phenylpropan-1-aminium
Benzenepropanaminium, gamma-cyclohexyl-N,N,N-triethyl-gamma-hydroxy-
(3-cyclohexyl-3-hydroxy-3-phenylpropyl)triethylazanium
(3-CYCLOHEXYL-3-HYDROXY-3-PHENYLPROPYL)TRIETHYLAMMONIUM
BENZENEPROPANAMINIUM, .GAMMA.-CYCLOHEXYL-N,N,N-TRIETHYL-.GAMMA.-HYDROXY-
DTXCID6028109
(3-cyclohexyl-3-hydroxy-3-phenylpropyl)-triethylazanium
UNII-7HE50A367X
Prestwick0_001042
Prestwick1_001042
Prestwick2_001042
Prestwick3_001042
SCHEMBL94230
BSPBio_000964
SPBio_002902
BPBio1_001062
CHEMBL1201354
DB00505
NCGC00179360-01
NCGC00179360-05
AB00514015
NS00004501
C07861
L001320
Q7841414
BRD-A22152765-003-10-0
Benzenepropanaminium,g-cyclohexyl-N,N,N-triethyl-g-hydroxy-