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3-Cyclohexyl-3-phenylazetidin-2-one

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Identification
Molecular formula
C15H19NO
CAS number
55051-04-8
IUPAC name
3-cyclohexyl-3-phenyl-azetidin-2-one
State
State

At room temperature, it is a solid and is often used in its solid state for various applications, especially in research and development contexts involving cyclic and aromatic compounds.

Melting point (Celsius)
110.00
Melting point (Kelvin)
383.15
Boiling point (Celsius)
280.00
Boiling point (Kelvin)
553.15
General information
Molecular weight
243.33g/mol
Molar mass
243.3340g/mol
Density
1.1234g/cm3
Appearence

3-Cyclohexyl-3-phenylazetidin-2-one is typically a white crystalline solid, characterized by its distinct cyclic and aromatic features due to the phenyl ring attached to the azetidinone core.

Comment on solubility

Solubility of 3-cyclohexyl-3-phenyl-azetidin-2-one

The compound 3-cyclohexyl-3-phenyl-azetidin-2-one, known for its unique structure, displays interesting solubility characteristics. Understanding its solubility is essential for applications in various chemical processes and formulations.

Key Solubility Insights:

  • Solvent Polarity: The solubility of this compound is influenced by the polarity of the solvent used. Generally, it is more soluble in non-polar solvents compared to polar ones, due to its hydrophobic cyclohexyl and phenyl groups.
  • Temperature Effects: Like many organic compounds, an increase in temperature may enhance solubility, allowing for better dissolution in chosen solvents.
  • Concentration Dependence: At higher concentrations, solubility can become limited and could lead to precipitation, particularly in polar environments.
  • Interactions with Other Substances: Its solubility can also be affected by the presence of other solutes, which can alter the solvent environment and, consequently, the solubility of 3-cyclohexyl-3-phenyl-azetidin-2-one.

In summary, the solubility of 3-cyclohexyl-3-phenyl-azetidin-2-one is a complex interplay of factors, primarily dictated by solvent choice, temperature, and concentration. Understanding these factors can help chemists effectively utilize this compound in various applications.

Interesting facts

Exploring 3-Cyclohexyl-3-phenyl-azetidin-2-one

3-Cyclohexyl-3-phenyl-azetidin-2-one is a fascinating compound that belongs to the class of azetidinones, which are four-membered cyclic amides known for their unique structural features and diverse applications in pharmaceutical chemistry.

Key Features and Applications

  • Structural Versatility: The presence of both cyclohexyl and phenyl groups in its structure provides remarkable lipophilicity, enhancing the compound's ability to interact with biological membranes.
  • Pharmacological Relevance: Compounds like 3-cyclohexyl-3-phenyl-azetidin-2-one have been studied for their potential as drug candidates, particularly in the treatment of various diseases including cancer and neurodegenerative disorders.
  • Synthetic Opportunities: This compound can be synthesized through various routes, facilitating its incorporation into complex chemical libraries for further research and development.
  • Cyclic Structures: Azetidinones like this one are relatively rare in nature, making them exciting subjects of study for chemists and biochemists alike.

Why It Stands Out

One particularly interesting aspect of 3-cyclohexyl-3-phenyl-azetidin-2-one is its potential to act as a scaffold for generating novel pharmacophores, inviting researchers to explore modifications that could tailor its activity. As quoted in many research discussions: "The cyclic nature of azetidinones allows for a unique interplay between sterics and electronics, leading to innovative drug design."

In summary, the study of 3-cyclohexyl-3-phenyl-azetidin-2-one exemplifies the intriguing intersection of chemistry and pharmacology, making it a compound of interest for both academic research and practical applications in drug discovery.

Synonyms
3-cyclohexyl-3-phenylazetidin-2-one
17719-29-8
3-Cyclohexyl-3-phenyl-2-azetidinone
L 1724
BRN 0211659
3-Fenil-3-cicloesil-2-azetidinone [Italian]
2-AZETIDINONE, 3-CYCLOHEXYL-3-PHENYL-
3-Fenil-3-cicloesil-2-azetidinone
4-21-00-03828 (Beilstein Handbook Reference)
DTXSID90938904
3-Cyclohexyl-3-phenyl-3,4-dihydroazet-2-ol